Glycine and d-serine act as positive modulators of signal transduction at N-methyl-d-aspartate sensitive glutamate receptors in cultured cerebellar granule cells

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

1983 • 1,400 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

Glutamate activates multiple single channel conductances in hippocampal neurons

1987 • 691 citations

Non-competitive antagonists of excitatory amino acid receptors

1987 • 502 citations

Excitatory Amino Acid Neurotransmission: NMDA Receptors and Hebb-Type Synaptic Plasticity

1988 • 484 citations

The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells

1986 • 431 citations

Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons

1987 • 420 citations

Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain

1988 • 284 citations

Ketamine and phencyclidine cause a voltage-dependent block of responses to l-aspartic acid

1985 • 261 citations

Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes

1988 • 258 citations

Light microscopic autoradiographic localisation of [3H]glycine and [3H]strychnine binding sites in rat brain

1986 • 247 citations

Allosteric modulation of amino acid receptors : therapeutic implications

1989 • 187 citations

Ketamine acts as a non-competitive N-methyl-d-aspartate antagonist on frog spinal cord in vitro

1985 • 180 citations

Phencyclidine and related drugs bind to the activated receptor-channel complex in rat brain membranes

1987 • 170 citations

Determination of the Equilibrium Dissociation Constants and Number of Glycine Binding Sites in Several Areas of the Rat Central Nervous System, Using a Sodium‐Independent System

1981 • 169 citations

Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain

1987 • 160 citations

Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel

1987 • 140 citations

Biochemical Aspects of Transmission at Inhibitory Synapses: The Role of Glycine

1978 • 136 citations

Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo

1989 • 122 citations

Different coupling of excitatory amino acid receptors with Ca2+ channels in primary cultures of cerebellar granule cells

1985 • 110 citations

Evidence for an endogenous peptide ligand for the phencyclidine receptor

1984 • 102 citations

Antagonism of phencyclidine-induced hyperactivity by glycine in mice

1986 • 94 citations

Magnesium Ions Inhibit the Stimulation of Inositol Phospholipid Hydrolysis by Endogenous Excitatory Amino Acids in Primary Cultures of Cerebellar Granule Cells

1987 • 85 citations

Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors.

1987 • 68 citations

Glycine modulation of the phencyclidine binding site in mammalian brain

1988 • 63 citations

Autoradiographic distribution of phencyclidine receptors in the rat brain using [3H]1-(1-(2-thienyl)cyclohexyl)piperidine ([3H]TCP)

1986 • 50 citations

Phencyclidine and glycine modulate NMDA-activated high conductance cationic channels by acting at different sites

1988 • 46 citations

High-affinity glycine binding sites in rat CNS: Regional variation and strychnine sensitivity

1978 • 36 citations

Classification and Allosteric Modulation of Excitatory Amino Acid Signal Transduction in Brain Slices and Primary Cultures of Cerebellar Neurons

1988 • 29 citations

Neurobiology of Amino Acids, Peptides and Trophic Factors

1989 • 7 citations