Peripheral group I metabotropic glutamate receptors modulate nociception in mice

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1988 • 4,963 citations

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

The formalin test: an evaluation of the method

1992 • 2,414 citations

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

1999 • 724 citations

The formalin test: scoring properties of the first and second phases of the pain response in rats

1995 • 585 citations

Central nervous system plasticity in the tonic pain response to subcutaneous formalin injection

1990 • 545 citations

Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity

1996 • 474 citations

Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin

1995 • 358 citations

CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.

1999 • 324 citations

3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

1994 • 270 citations

Opioid receptors on peripheral sensory axons

1997 • 232 citations

mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia

2001 • 227 citations

Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats

1996 • 227 citations

Ultrastructural analysis of NMDA, AMPA, and kainate receptors on unmyelinated and myelinated axons in the periphery

1998 • 227 citations

Ultrastructural analysis of NMDA, AMPA, and kainate receptors on unmyelinated and myelinated axons in the periphery

1998 • 214 citations

Peripheral NMDA and non-NMDA glutamate receptors contribute to nociceptive behaviors in the rat formalin test

1997 • 205 citations

Formalin-induced release of excitatory amino acids in the skin of the rat hindpaw

1998 • 188 citations

Formalin induces biphasic activity in C-fibers in the rat

1996 • 184 citations

Glutamate participates in the peripheral modulation of thermal hyperalgesia in rats

1995 • 182 citations

Amino acid release into the knee joint: key role in nociception and inflammation

2000 • 179 citations

A novel class of antagonists for metabotropic glutamate receptors, 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates

1996 • 178 citations

Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input

1995 • 175 citations

Peripheral glutamate release in the hindpaw following low and high intensity sciatic stimulation

2000 • 173 citations

The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception

1996 • 168 citations

Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn

1999 • 166 citations

Requirement of Metabotropic Glutamate Receptors for the Generation of Inflammation‐evoked Hyperexcitability in Rat Spinal Cord Neurons

1994 • 162 citations

Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CA1 pyramidal cell excitability

1995 • 159 citations

Evidence for the interaction of glutamate and NK1 receptors in the periphery

1998 • 144 citations

(+)-2-Methyl-4-carboxyphenylglycine (LY367385) selectively antagonises metabotropic glutamate mGluR1 receptors

1997 • 136 citations

Role of Metabotropic Glutamate Receptor Subtype mGluR1 in Brief Nociception and Central Sensitization of Primate STT Cells

1999 • 136 citations

Regeneration of periodontal primary afferents of the rat incisor following injury of the inferior alveolar nerve with special reference to neuropeptide Y-like immunoreactive primary afferents

1997 • 131 citations

Excitatory amino acid profiles of synovial fluid from patients with arthritis.

2000 • 116 citations

Metabotropic glutamate receptor mRNA expression in rat spinal cord

1997 • 106 citations

Cellular, and subcellular localization of the mGluR5a metabotropic glutamate receptor in rat spinal cord

1994 • 101 citations

Comparison of nociceptive effects produced by intrathecal administration of mGluR agonists

1996 • 100 citations

mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study

1997 • 89 citations

Hyperalgesia and allodynia induced by intrathecal (RS)-dihydroxyphenylglycine in rats

1998 • 83 citations

Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats

1998 • 80 citations

Direct effects of metabotropic glutamate receptor compounds on native and recombinant N -methyl- <scp>d</scp> -aspartate receptors

1998 • 74 citations

Electrophysiological Assessment of the Cutaneous Arborization of Aδ-Fiber Nociceptors

1999 • 72 citations

Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones

2000 • 59 citations

Glutamate receptors on postganglionic sympathetic axons

1998 • 40 citations

Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist

1995 • 36 citations