Regulation of fatty-acid synthesis in higher animals

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

OBESE, A NEW MUTATION IN THE HOUSE MOUSE*

1950 • 1,020 citations

THE STRUCTURE OF WATER AND HYDROPHOBIC BONDING IN PROTEINS. III. THE THERMODYNAMIC PROPERTIES OF HYDROPHOBIC BONDS IN PROTEINS^1,2

1962 • 967 citations

Cyclic AMP

1968 • 954 citations

Adenosine Triphosphate Conservation in Metabolic Regulation

1967 • 878 citations

The Interaction of Human Serum Albumin with Long-chain Fatty Acid Anions

1958 • 743 citations

Biochemistry of Mitochondria

1966 • 694 citations

Control of Enzyme Levels in Animal Tissues

1970 • 680 citations

Studies on the Synthesis and Degradation of Proteins of the Endoplasmic Reticulum of Rat Liver

1969 • 538 citations

AVIDIN. 1. THE USE OF [14C]BIOTIN FOR KINETIC STUDIES AND FOR ASSAY

1963 • 476 citations

Binding of long-chain fatty acids to bovine serum albumin

1969 • 475 citations

Carnitine and Its Role in Fatty Acid Metabolism* *Work reviewed from this laboratory was supported by grants A-1465 and A-1682 from the National Institutes of Health.

1963 • 446 citations

MALIC ENZYME AND LIPOGENESIS

1964 • 431 citations

Studies on the mechanism of fatty acid synthesis

1960 • 408 citations

The Importance of Both Synthesis and Degradation in the Control of Arginase Levels in Rat Liver

1964 • 396 citations

Studies on the Metabolism of Adipose Tissue

1964 • 390 citations

Metabolic and Hormonal Control of Phosphoenolpyruvate Carboxykinase and Malic Enzyme in Rat Liver

1963 • 388 citations

Metabolic Control of Enzymes Involved in Lipogenesis and Gluconeogenesis^*

1964 • 360 citations

Influence of turnover rates on the responses of enzymes to cortisone.

1965 • 348 citations

Variations in tissue contents of coenzyme A thio esters and possible metabolic implications

1964 • 343 citations

Effects of Antecedent Food Intake Pattern on Hepatic Lipogenesis

1958 • 343 citations

A MALONIC ACID DERIVATIVE AS AN INTERMEDIATE IN FATTY ACID SYNTHESIS

1958 • 338 citations

Studies on the Mechanism of Activation of Acetyl Coenzyme A Carboxylase by Citrate

1963 • 333 citations

The Mechanism of Tricarboxylic Acid Cycle Regulation of Fatty Acid Synthesis

1962 • 333 citations

Carnitine in Intermediary Metabolism

1962 • 321 citations

Extent and Patterns of Adaptation of Enzyme Activities in Livers of Normal Rats Fed Diets High in Glucose and Fructose

1960 • 312 citations

The Control of Lipid Metabolism

1963 • 298 citations

The relative significance of acetate and glucose as precursors for lipid synthesis in liver and adipose tissue from ruminants

1967 • 294 citations

The role of biotin-dependent carboxylations in biosynthetic reactions

1967 • 283 citations

The Pentose Cycle, Triose Phosphate Isomerization, and Lipogenesis in Rat Adipose Tissue

1966 • 282 citations

Evidence for the participation of biotin in the enzymic synthesis of fatty acids

1958 • 282 citations

The Supply of Precursors for the Synthesis of Fatty Acids

1962 • 277 citations

Inhibition of fatty acid synthetases by the antibiotic cerulenin

1972 • 273 citations

Effect of (—)-Hydroxycitrate on Fatty Acid Synthesis by Rat Liver in Vivo

1971 • 272 citations

The Effect of Palmityl Coenzyme A on Glucose 6-Phosphate Dehydrogenase and Other Enzymes

1966 • 272 citations

Tricarballylate and hydroxycitrate: Substrate and inhibitor of ATP: Citrate oxaloacetate lyase

1969 • 259 citations

Regulation of phosphofructokinase activity by citrate in normal and diabetic muscle

1963 • 254 citations

Liver acetyl CoA carboxylase and fatty acid synthetase: Relative activities in the normal state and in hereditary obesity

1967 • 253 citations

Purification of Rat Liver Acetyl Coenzyme A Carboxylase and Immunochemical Studies on its Synthesis and Degradation

1970 • 250 citations

Studies on the Mechanism of Fatty Acid Synthesis

1962 • 246 citations

Carnitine in Intermediary Metabolism

1963 • 241 citations

Citrate and the Conversion of Carbohydrate into Fat

1970 • 236 citations

Changes in lipid synthesis in rat liver during development

1967 • 230 citations

Metabolite transport in mitochondria: an example for intracellular membrane function.

1970 • 229 citations

Paths of Carbon in Gluconeogenesis and Lipogenesis

1966 • 229 citations

Fatty acid synthesis during fat-free refeeding of starved rats

1965 • 227 citations

The Biotin‐Dependent Enzymes

1971 • 224 citations

Gluconeogenesis and lipogenesis in tissue from ruminant and nonruminant animals.

1969 • 219 citations

Acetyl Coenzyme A Carboxylase

1969 • 218 citations

Acetyl coenzyme A carboxylase.

1974 • 216 citations

Participation of acyl?coa in carbon chain biosynthesis

1959 • 211 citations

Kinetic Study of the Tricarboxylate Carrier in Rat Liver Mitochondria

1972 • 208 citations

Patterns of dietary and hormonal induction of certain NADP-linked liver enzymes

1964 • 206 citations

The problem of tissue sampling from experimental animals with respect to freezing technique, anoxia, stress and narcosis

1972 • 205 citations

CITRATE AND THE CONVERSION OF CARBOHYDRATE INTO FAT. THE ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF STARVED AND RE-FED RATS

1965 • 197 citations

Studies on the mechanism of fatty acid synthesis V. Bicarbonate requirement for the synthesis of long-chain fatty acids

1958 • 194 citations

Size Distribution of Membrane Proteins of Rat Liver and Their Relative Rates of Degradation

1971 • 192 citations

Liver Acetyl Coenzyme A Carboxylase

1968 • 192 citations

Studies on Rat Adipose Tissue in Vitro

1962 • 190 citations

Fatty acid synthesis during early linoleic acid deficiency in the mouse

1965 • 186 citations

Synthesis and degradation of the lipogenic enzymes of rat liver

1972 • 186 citations

The Concentration of Malonyl-Coenzyme A and the Control of Fatty Acid Synthesis in Vivo

1972 • 182 citations

The inhibition of malate, tricarboxylate and oxoglutarate entry into mitochondria by 2-n-butylmalonate

1967 • 181 citations

Biosynthesis of saturated fatty acids.

1961 • 181 citations

THE INHIBITION OF ACETYL COA CARBOXYLASE BY LONG CHAIN ACYL COA DERIVATIVES.

1963 • 177 citations

Studies on Rat Adipose Tissue in Vitro

1958 • 174 citations

Changes in hepatic lipogenesis during development of the rat

1967 • 171 citations

Rat Liver Pyruvate Carboxylase

1971 • 169 citations

Enzyme Activities Related to Fatty‐Acid Synthesis in Liver and Adipose Tissue of Rats Treated with Triiodothyronine

1972 • 169 citations

Pyruvate Carboxylase

1966 • 169 citations

Metabolic Roles of Citrate

1967 • 168 citations

Interaction of Homologous Alkyl Sulfates with Bovine Serum Albumin

1949 • 167 citations

Carnitine in Intermediary Metabolism

1962 • 165 citations

Rat Liver Glucose 6-Phosphate Dehydrogenase

1971 • 164 citations

1-Acylglycerol 3-Phosphate Acyltransferase from Rat Liver

1969 • 162 citations

Biosynthesis of Fatty Acids

1963 • 157 citations

Acetyl-Coenzyme-A Carboxylase from Rat Liver. Subunit Structure and Proteolytic Modification

1975 • 151 citations

Localization of the Block in Lipogenesis Resulting from Feeding Fat

1963 • 149 citations

The utilization of acetic, propionic and butyric acids by fattening sheep

1957 • 147 citations

The effect of starvation and alloxan-diabetes on the contents of citrate and other metabolic intermediates in rat liver

1968 • 146 citations

The Regulation of Fatty Acid Biosynthesis in Rat Hepatomas

1968 • 145 citations

The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of insulin, adrenaline and some metabolites in vitro

1970 • 145 citations

The Tricarboxylic Acid Cycle

1954 • 145 citations

Regulation of fatty acid synthesis at the acetyl-CoA carboxylation step

1965 • 142 citations

Selective dampening of lipogenic enzymes of liver by exogenous polyunsaturated fatty acids

1970 • 142 citations

Some physical properties of palmityl-coenzyme a micelles

1968 • 141 citations

The Metabolism of Tritiated Glucose by Rat Adipose Tissue

1966 • 139 citations

Transcarboxylase

1969 • 139 citations

Biosynthesis of fatty acids: IV. Studies with inhibitors

1963 • 138 citations

Mechanism of the Propionyl Carboxylase Reaction

1961 • 137 citations

Palmityl-coenzyme a inhibition of the citrate-condensing enzyme

1965 • 137 citations

Citrate-cleavage enzyme, ‘malic’ enzyme and certain dehydrogenases in embryonic and growing chicks

1968 • 135 citations

Molecular characteristics of liver acetyl CoA carboxylase.

1966 • 134 citations

Inhibition of lipogenesis in rat liver by (−)-hydroxycitrate

1972 • 131 citations

Inhibition of mammary gland acetyl CoA carboxylase by fatty acids

1963 • 130 citations

Turnover and Exchange of Ribosomal Proteins from Rat Liver

1972 • 130 citations

Studies on the portal blood of sheep. 2. Absorption of volatile fatty acids from the rumen of the sheep

1957 • 129 citations

Fatty Acid Synthetase from Lactating Rat Mammary Gland

1970 • 126 citations

Current topics in cellular regulation. Vol. 23

1985 • 125 citations

Mechanism of the Propionyl Carboxylase Reaction

1962 • 124 citations

Citrate cleavage in adipose tissue.

1965 • 123 citations

The Citrate Enzymes: Their Structures, Mechanisms, and Biological Functions

1972 • 123 citations

Incorporation of malonyl CoA into fatty acids by liver in starvation and alloxan-diabetes

1960 • 122 citations

The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of altered dietary and hormonal conditions

1970 • 122 citations

The Molecular Physiology of Citrate

1965 • 120 citations

The stimulation of fatty acid synthesis by isocitrate and malonate

1962 • 120 citations

The Effect of Palmityl Coenzyme A on Pigeon Liver Fatty Acid Synthetase

1968 • 114 citations

Paths of Carbon in Gluconeogenesis and Lipogenesis

1966 • 114 citations

Citrate Cleavage Enzyme in Livers of Obese and Nonobese Mice

1964 • 113 citations

The Effects of Nutritional and Hormonal Factors on the Fatty Acid Synthetase Level of Rat Liver

1969 • 112 citations

Liver Acetyl Coenzyme A Carboxylase

1968 • 108 citations

Lipid Metabolism

1964 • 107 citations

THE COMBINATION OF ORGANIC ANIONS WITH SERUM ALBUMIN

1952 • 106 citations

Effects of Magnesium Ions, Adenosine Triphosphate, Palmitoylcarnitine, and Palmitoyl Coenzyme A on Acetyl Coenzyme A Carboxylase

1968 • 106 citations

Acetyl CoA carboxylase. I. Requirement for two protein fractions.

1968 • 105 citations

Enzyme Patterns in Rat Liver and Morris Hepatoma 5123 during Metabolic Transitions

1961 • 105 citations

Synthesis and Degradation of Malic Enzyme in Chick Liver

1971 • 104 citations

An Alternate Pathway of α-Ketoglutarate Catabolism in the Isolated, Perfused Rat Liver

1965 • 103 citations

Acetyl Coenzyme A Carboxylase from Rat Liver

1972 • 102 citations

Current Trends in the Biochemistry of Lipids

1973 • 101 citations

The evaluation of the rates of biological processes from tracer kinetic data. I. The influence of labile metabolic pools

1962 • 98 citations

Evidence for Regulation of Cholesterol and Fatty Acid Synthesis in Liver by Cyclic Adenosine 3′,5′-Monophosphate

1972 • 98 citations

The Metabolic Roles of Citrate

1969 • 97 citations

Hydrogen transfer in fatty acid synthesis by rat liver and mammary-gland cell-free preparations studied with tritium-labelled pyridine nucleotides and glucose

1963 • 96 citations

Citrate content of liver and kidney of rat in various metabolic states and in fluoroacetate poisoning

1967 • 96 citations

Effect of dietary change on the rates of synthesis and degradation of rat liver fatty acid synthetase

1972 • 96 citations

Rat Liver Pyruvate Carboxylase

1971 • 96 citations

Metabolism of Fatty Acids

1969 • 95 citations

CITRATE AND THE CONVERSION OF CARBOHYDATE INTO FAT. ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF NORMAL AND DIABETIC RATS

1965 • 95 citations

Acetyl CoA carboxylase

1971 • 91 citations

Acetyl Coenzyme A Carboxylase: Filamentous Nature of the Animal Enzymes

1969 • 90 citations

Studies on the ketogenic effect of glucagon in intact rat liver

1966 • 89 citations

LIVER ACETYL COA CARBOXYLASE: THE DISSOCIATION-REASSOCIATION PROCESS AND ITS RELATION TO CATALYTIC ACTIVITY

1966 • 89 citations

The Metabolism of Propionic Acid

1964 • 89 citations

Lipid Metabolism

1962 • 87 citations

Incorporation of radioactive citrate into fatty acids

1962 • 85 citations

On the response of hepatic glucose-6-phosphate dehydrogenase activity to changes in diet composition and food intake pattern

1963 • 85 citations

Inhibition of Hepatic Acetyl Coenzyme A Carboxylase by Hypolipidemic Agents

1969 • 85 citations

Factors involved in changes in hepatic lipogenesis during development of the rat

1970 • 84 citations

Pyruvate Carboxylase from Chicken Liver

1972 • 84 citations

The incorporation of citrate carbon into fatty acids

1963 • 84 citations

Effects of carnitine on acetyl-CoA oxidation by heart muscle mitochondria

1964 • 83 citations

THE COMBINATION OF ORGANIC ANIONS WITH SERUM ALBUMIN

1948 • 82 citations

Citrate Cleavage Enzyme and Fatty Acid Synthesis

1968 • 80 citations

Changes in the level of the fatty acid synthesizing enzymes during starvation

1962 • 80 citations

The Pathway of Hydrogen in Biosyntheses

1961 • 79 citations

Role of Acetyl Coenzyme A Carboxylase in the Control of Fatty Acid Synthesis

1971 • 79 citations

Study and evaluation of regulation of enzyme activity and synthesis in mammalian liver

1963 • 79 citations

Effect of size on the relative rate of degradation of rat liver soluble proteins

1970 • 79 citations

On the Mode of Action of Lipid-lowering Agents

1971 • 78 citations

ACETYL COA CARBOXYLASE, II. DEMONSTRATION OF BIOTIN-PROTEIN AND BIOTIN CARBOXYLASE SUBUNITS

1969 • 77 citations

Studies on ATP Citrate Lyase of Rat Liver

1966 • 77 citations

Regulation of Fatty Acid Biosynthesis* *The unpublished experimental work from this laboratory presented here and the preparation of this article have been assisted by grants from the National Institutes of Health (R01-HE-10406) and the National Science Foundation (GB-5142X).

1971 • 76 citations

Nicotinamide adenine dinucleotide phosphate-specific dehydrogenases in relation to lipogenesis

1964 • 75 citations

The Effects of 2‐Ethylcitrate and Tricarballylate on Citrate Transport in Rat Liver Mitochondria and Fatty Acid Synthesis in Rat White Adipose Tissue

1970 • 72 citations

Fatty acid synthesis in developing mouse liver

1970 • 72 citations

Effects of Palmitoyl CoA on Citrate and Malate Transport by Rat Liver Mitochondria

1972 • 71 citations

Interrelationships between liver composition, plasma glucose and ketones, and hepatic acetyl-CoA and citric acid during prolonged starvation in the male rat

1968 • 71 citations

The subcelular distrbution of short-chain fatty acyl-CoA synthetase activity in rat tissues

1971 • 70 citations

Rat Mammary Acetyl Coenzyme A Carboxylase

1969 • 70 citations

Insulin Action in Alloxan Diabetes Modified by Actinomycin D

1964 • 68 citations

Enzymatic Carboxylation of Biotin: Molecular and Catalytic Properties of a Component Enzyme of Acetyl CoA Carboxylase

1970 • 67 citations

Fatty acid biosynthesis and the role of the acyl carrier protein.

1967 • 65 citations

Acetyl Coenzyme A Carboxylase

1972 • 64 citations

Liver acetyl CoA carboxylase: insight into the mechanism of activation by tricarboxylic acids and acetyl CoA.

1967 • 64 citations

kinetic Studies on the Reaction Mechanism and the Citrate Activation or Liver Acetyl Coenzyme A Carboxylase

1971 • 63 citations

Carnitine-coenzyme A transacetylase in mitochondria from various organs

1964 • 63 citations

Mechanism of Biotin Action

1970 • 61 citations

Metabolic Changes in Liver Associated with Spontaneous Ketosis and Starvation in Cows

1968 • 61 citations

Relationship between nutritional status and fatty acid synthesis by microsomal and soluble enzymes of pigeon liver

1966 • 60 citations

ELEVATION OF LONG CHAIN ACYL COA DERIVATIVES IN LIVERS OF FASTED RATS.

1963 • 60 citations

Fatty Acid Synthetase from Lactating Rat Mammary Gland

1971 • 60 citations

Transcarboxylase

1969 • 60 citations

Activation of acetyl-CoA carboxylase and associated alteration of sedimentation characteristics of the enzyme

1962 • 59 citations

Effect of diet on individual volatile fatty acids in the rumen of sheep, with particular reference to the effect of low rumen pH and adaptation on high-starch diets

1957 • 57 citations

On the Possible Involvement of a Carbonyl Phosphate Intermediate in the Adenosine Triphosphate-dependent Carboxylation of Biotin

1972 • 57 citations

Inhibition of hepatic lipogenesis by cyclic-3′,5′-nucleotide monophosphates

1972 • 57 citations

Studies on the Mechanism of Fatty Acid Synthesis

1968 • 57 citations

Pathway for the Synthesis of Fatty Acids in Mammalian Tissues

1972 • 55 citations

Interrelationship and control of glucose metabolism and lipogenesis in isolated fat-cells. Control of pentose phosphate-cycle activity by cellular requirement for reduced nicotinamide adenine dinucleotide phosphate

1972 • 54 citations

Citrate and the conversion of carbohydrate into fat. Citrate cleavage in obesity and lactation

1966 • 54 citations

Rat Liver Pyruvate Carboxylase

1971 • 54 citations

Acetyl-CoA carboxylase from rat adipose tissue

1969 • 53 citations

Studies on the induction of liver glucose-6-phosphate dehydrogenase in the rat

1967 • 52 citations

The Role of Carnitine and Carnitine Acyltransferase in Biological Acetylations and Fatty Acid Synthesis

1966 • 52 citations

Pyruvate Carboxylase from Chicken Liver

1974 • 51 citations

Protein Turnover and 4'-Phosphopantetheine Exchange in Rat Liver Fatty Acid Synthetase

1971 • 51 citations

Acetyl coenzyme A carboxylase. Purification and properties of the bovine adipose tissue enzyme

1972 • 51 citations

Directions and patterns of adaptation induced in liver enzymes of the diabetic rat by the feeding of glucose and fructose

1962 • 51 citations

Citrate and the conversion of carbohydrate into fat. The regulation of fatty acid synthesis by rat liver extracts

1967 • 50 citations

Free fatty acids as lipogenic inhibitors

1964 • 49 citations

Fatty Acid Biosynthesis and the Role of the Acyl Carrier Protein1 1This investigation was supported in part by grants from the United States Public Health Service, AM-10550, HE-10406, the National Science Foundation, GB-5056X, GB-5142X, and the American Cancer Society PRA-33.

1967 • 49 citations

The Conversion of Glutamate Carbon to Fatty Acid Carbon via Citrate

1964 • 48 citations

Further evidence for polymeric structure of liver acetyl CoA carboxylase

1966 • 48 citations

Selective induction and suppression of liver enzyme synthesis

1962 • 47 citations

Lack of adaptation in lipogenesis by hepatoma 9121

1968 • 46 citations

Defective dietary control of fatty acid metabolism in four transplantable rat hepatomas: numbers 5123C, 7793, 7795, and 7800.

1968 • 45 citations

The Carboxyl Transferase Component of Acetyl CoA Carboxylase: Structural Evidence for Intersubunit Translocation of the Biotin Prosthetic Group

1971 • 45 citations

Dietary changes of cytoplasmic acetyl-CoA synthetase in different rat tissues

1972 • 44 citations

Acetyl-CoA carboxylase and citrate cleavage enzymein the rat mammary gland

1965 • 44 citations

Penetration of the mitochondrial membrane by tricarboxylic acid anions.

1968 • 44 citations

Lipogenesis in biotin deficiency

1968 • 44 citations

Citrate cleavage and acetate activation in livers of normal and diabetic rats

1964 • 44 citations

Concerning the form in which acetyl units produced in mitochondria are transferred to the site of denovofatty acid synthesis in the cell

1965 • 42 citations

Fat feeding and cholesterol synthesis

1967 • 42 citations

Primer Specificity of Mammary Fatty Acid Synthetase and the Role of the Soluble β-Oxidative Enzymes

1971 • 42 citations

Inhibition of hyperlipogenesis with puromycin or actinomycin D

1965 • 42 citations

Biosynthesis of fatty acids in mammary tissue

1969 • 41 citations

Citrate and the conversion of carbohydrate into fat.

1968 • 41 citations

The effect of dietary carbohydrate and fat on the synthesis of rat liver 6-phosphogluconate dehydrogenase

1971 • 39 citations

A Comparative Study of Reduced Di- and Triphosphopyridine Nucleotides in the Intact Cell

1961 • 39 citations

Hepatic Enzyme Activities in Streptozotocin-Diabetic Rats Before and After Insulin Treatment

1971 • 39 citations

Liver acetyl coenzyme A carboxylase: activation of model partial reactions by tricarboxylic acids.

1968 • 38 citations

A New Mutation in the House Mouse

1921 • 37 citations

Acetyl CoA Carboxylase: The Purified Transcarboxylase Component

1971 • 37 citations

Effects of D- and L-thyroxine on enzymes in liver and adipose tissue of rats

1968 • 37 citations

TRANSCARBOXYLASE, VIII. ISOLATION AND PROPERTIES OF A BIOTIN-CARBOXYL CARRIER PROTEIN

1969 • 36 citations

The role of ATP citrate lyase in the transfer of acetyl groups in rat liver

1968 • 35 citations

Studies on the Control of Fatty Acid Synthesis

1967 • 35 citations

Adaptive enzyme formation during hyperlipogenesis

1966 • 35 citations

The Effect of Fasting on Synthesis and 4′-Phosphopantetheine Exchange in Rat Liver Fatty Acid Synthetase

1972 • 35 citations

On the Mode of Action of Lipid-lowering Agents

1971 • 35 citations

Studies on ATP citrate lyase of rat liver.-1-Purification and some properties

1966 • 35 citations

Stimulation of fatty acid biosynthesis by phosphorylated sugars.

1966 • 34 citations

On the proposed relation of citrate enzymes to fatty acid synthesis and ketosis in starvation

1967 • 34 citations

Rat mammary-gland acetyl-coenzyme A carboxylase. Interaction with milk fatty acids

1970 • 33 citations

Biosynthesis of the Fatty Acid Synthetase by Isolated Rat Liver Cells

1969 • 33 citations

Mode of action of lipid-lowering agents. II. In vitro inhibition of acetyl coenzyme A carboxylase by a hypolipidemic drug

1970 • 33 citations

Studies on the Relationship betweeen Activity and Structure of Liver Acetyl‐CoA Carboxylase

1967 • 32 citations

The effect of dietary fat on lipogenic enzymes in the liver of the domestic fowl

1968 • 32 citations

Utilization of citric acid carbon for the biosynthesis of long-chain fatty acids

1962 • 31 citations

Fatty acid biosynthesis and RNA function in fasting, aging and diabetes

1966 • 31 citations

Relative turnover rates of subunits of rat liver fatty acid synthetase

1972 • 31 citations

Mechanism of tricarboxylic acid cycle regulation of fatty acid synthesis

1962 • 30 citations

Structure and function of the acyl carrier protein.

1966 • 30 citations

Purification and crystallization of acetyl CoA carboxylase

1967 • 30 citations

Autonomous cholesterol and fatty acid synthesis in hepatomas: Deletion of the adenosine 3′, 5′-cyclic monophosphate control mechanism of normal liver

1972 • 29 citations

Transcarboxylase

1970 • 29 citations

Biosynthesis of fatty acids in mammary tissue

1969 • 29 citations

The cellular control of fatty acid synthesis at the enzymatic level.

1963 • 29 citations

Regulation of Fatty Acid Synthesis in Animal Tissues

1971 • 28 citations

The Binding of Reduced Nicotinamide Adenine Dinucleotide Phosphate to Mammalian and Avian Fatty Acid Synthetases

1970 • 28 citations

Effect of magnesium ions and adenosine triphosphate on the activity of acetyl coenzyme a carboxylase

1967 • 28 citations

Acetyl Coenzyme A Carboxylase

1970 • 28 citations

On the Mode of Action of Lipid-lowering Agents

1972 • 28 citations

The effects of palmitylcarnitine on hepatic fatty acid synthesis and on acetyl CoA carboxylase activity

1966 • 27 citations

Liver Acetyl‐Coenzyme‐A Carboxylase

1971 • 27 citations

Effect of Alloxan-Diabetes on the Activity of Citrate Cleavage Enzyme in Adipose Tissue

1965 • 26 citations

Acetyl group transfer in lipogenesis

1968 • 26 citations

Microsomes, Microsomal Phospholipids, and Fatty Acid Synthesis

1969 • 25 citations

Citrate metabolism in diabetes

1966 • 25 citations

Konzentrationsänderungen von Effektoren gluconeogenetischer Schlüsselenzyme in der Rattenleber unter gluconeogenetischen Bedingungen

1967 • 24 citations

Alterations in the sensitivity to effectors of rat liver acetyl-CoA carboxylase following trypsin treatment

1969 • 24 citations

Synthesis and Degradation of Liver Acetyl Coenzyme A Carboxylase in Genetically Obese Mice

1971 • 23 citations

The Absolute Configuration of Naturally Occurring Isocitric Acid

1962 • 23 citations

Tricarboxylic Acid Activator-Induced Changes at the Active Site of Acetyl-CoA Carboxylase

1971 • 23 citations

[2] Acetyl-CoA carboxylase from chicken and rat liver

1969 • 23 citations

Effect of development on chicken liver acetyl-coenzyme A carboxylase

1970 • 23 citations

The activities of citrate cleavage enzyme, acetyl-CoA synthetase and lipoprotein lipase in white and brown adipose tissue and the liver of the rat during development

1966 • 22 citations

The evaluation of the rates of biological processes from tracer kinetic data

1968 • 21 citations

Fatty acyl thio esters of coenzyme A: Inhibition of fatty acid synthesis in vitro and determination of levels in liver in normal, fasted, and fat- or sugar-fed rats

1963 • 20 citations

The activation of rat liver acetyl-CoA carboxylase by trypsin.

1967 • 20 citations

The co-ordinated inhibition of protein and lipid biosynthesis by adenosine 3′:5′-cyclic monophosphate

1970 • 20 citations

On the mode of action of lipid-lowering agents. 3. Kinetics of activation and inhibition of acetyl coenzyme A carboxylase.

1970 • 20 citations

Intracelluar localizaion of fatty acid synthesis in chick-embryo liver and stimulation of synthesis by exogenous glucose

1971 • 20 citations

Citrate metabolism in diabetes

1967 • 19 citations

Constant and specific proportion groups of enzymes in rat mammary gland and adipose tissue in relation to lipogenesis

1972 • 19 citations

Hepatic Acetyl CoA Carboxylase, Propionyl CoA Carboxylase and Pyruvate Carboxylase Activities During Embryonic Development and Growth in Chickens

1970 • 19 citations

On the Mode of Action of Lipid-lowering Agents

1970 • 18 citations

Transcarboxylase

1970 • 16 citations

Dietary regulation of fatty acid synthesis in rat liver and hepatic autotransplants

1972 • 16 citations

Rôle modeste du citrate comme transporteur d'acétyl‐CoA chez l'animal vivant.

1971 • 14 citations

Multienzyme Complex of Fatty Acid Synthetase

1967 • 14 citations

The effect of thyroxine on citrate cleavage enzyme and NADP linked dehydrogenase activities

1965 • 13 citations

The supply of precursors for the extramitochondrial synthesis of fatty acids.

1963 • 13 citations

Studies on ATP Citrate Lyase of Rat Liver

1967 • 11 citations

Effect of alloxan and portacaval shunt on the synthesis of fatty acids and sterols by rat liver

1968 • 9 citations

Tissue Content of Citrate and Citrate-cleavage Enzyme Activity during Starvation and Refeeding

1967 • 9 citations

Adrenocorticotropin Stimulation of 2-Ketoglutarate Oxidation by Isolated Rat Epididymal Adipose Tissue

1970 • 9 citations

The citrate cleavage enzyme activity in chick embryo and chicken liver during development

1967 • 8 citations

Über den Stoffwechsel der freien Essigsäure im Tierkörper und seine Beziehung zum Atherogeneseproblem

1964 • 7 citations

Effects of cyclic-3′, 5′-adenosine monophosphate and of dibutyryl-3′, 5′-adenosine monophosphate on the fatty acid synthesizing system of rat brown adipose tissue

1971 • 7 citations

Regulatory mechanisms for liver acetyl-coenzyme A carboxylase

1972 • 6 citations

The presence of acetyl-coenzyme A carboxylase apoenzyme in the liver of newly hatched chicks

1972 • 6 citations

Lichtstreuungsmessungen mit der polymeren Form der Acetyl-CoA-Carboxylase aus Hühnerleber

1972 • 5 citations

Citrate and Isocitrate Transport in Isolated Rat Liver Mitochondria

1970 • 5 citations

ADAPTIVE BEHAVIOR OF CITRATE CLEAVAGE ENZYME**Supported by NSF GB 3412.

1965 • 2 citations

[Light-scattering studies on the polymeric form of chicken liver acetyl-CoA carboxylase].

1972 • 1 citations

Zur St�rung der Fettsynthese beim Diabetes

2015 • 1 citations