Mechanism and subcellular localization of secretory IgM polymer assembly.

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Brefeldin A: insights into the control of membrane traffic and organelle structure.

1992 • 1,848 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

Protein degradation in the endoplasmic reticulum

1990 • 659 citations

Cell Biology of von Willebrand Factor

1990 • 604 citations

Pre- and post-golgi vacuoles operate in the transport of semliki forest virus membrane glycoproteins to the cell surface

1984 • 523 citations

Multisubunit assembly of an integral plasma membrane channel protein, gap junction connexin43, occurs after exit from the ER

1993 • 492 citations

Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins

1989 • 466 citations

Regulation of Protein Export From the Endoplasmic Reticulum

1988 • 421 citations

Oligomerization is essential for transport of vesicular stomatitis viral glycoprotein to the cell surface

1986 • 417 citations

Complement Fixation on Cell Surfaces by 19 S and 7 S Antibodies

1965 • 336 citations

Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment.

1992 • 277 citations

Immunoglobulin M and Secretory Immunoglobulin A: Presence of a Common Polypeptide Chain Different from Light Chains

1971 • 245 citations

Developmental regulation of IgM secretion: The role of the carboxy-terminal cysteine

1990 • 245 citations

Plasma cell immunoglobulin M molecules. Their biosynthesis, assembly, and intracellular transport.

1979 • 242 citations

The Coming of Age of the Immunoglobulin J Chain

1985 • 207 citations

Formation of intermolecular disulfide bonds on nascent immunoglobulin polypeptides.

1979 • 147 citations

Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation.

1993 • 141 citations

Temperature and energy dependence of secretory protein transport in the exocrine pancreas.

1986 • 140 citations

Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents

1990 • 131 citations

Immunoglobin M biosynthesis. Intracellular accumulation of 7s subunits

1969 • 116 citations

Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Requirement for J chain and a disulphide-exchanging enzyme for polymerization

1973 • 116 citations

On the structure of polymeric IgM

1988 • 115 citations

Bidirectional membrane traffic between the endoplasmic reticulum and Golgi apparatus

1993 • 111 citations

The conformational effects of N‐glycosylation on the tailpiece from serum IgM

1991 • 105 citations

Deletions in immunoglobulin mu chains.

1982 • 98 citations

Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells.

1992 • 97 citations

IgM - molecular requirements for its assembly and function

1989 • 92 citations

Role of disulfide interchange enzyme in immunoglobulin synthesis

1981 • 90 citations

Modulation of Adenylate Cyclase/Cyclic AMP Response by Thyrotropin and Prostaglandin E2 in Cultured Thyroid Cells. 1. Negative Regulation

1978 • 86 citations

The biological effects of IgM hexamer formation

1990 • 80 citations

J chain synthesis and secretion of hexameric IgM is differentially regulated by lipopolysaccharide and interleukin 5.

1992 • 78 citations

Induction of Immunoglobulin M Synthesis and Secretion in Bone-Marrow-Derived Lymphocytes by Locally Concentrated Concanavalin A

1973 • 69 citations

Immunoglobulin M biosynthesis. Production of intermediates and excess of light chain in mouse myeloma MOPC 104E

1971 • 62 citations

Biosynthesis of immunoglobulins

1972 • 58 citations

Assembly of immunoglobulin M. Blocked thiol groups of intracellular 7S subunits

1971 • 56 citations

Ultrastructural studies of human lymphoid cells. mu and J chain expression as a function of B cell differentiation.

1983 • 53 citations

Major carbohydrate structures at five glycosylation sites on murine IgM determined by high resolution 1H-NMR spectroscopy

1985 • 53 citations

IgM hexamers?

1994 • 44 citations

Structure of the oligosaccharides of mouse immunoglobulin M secreted by the MOPC 104E plasmacytoma

1980 • 39 citations

The carbohydrate composition of human myeloma IgA

1972 • 31 citations

Characterization of a presecretory phase in B-cell differentiation.

1989 • 30 citations

Quantitation of cell surface molecules on a differentiating, Ly-1+ B cell lymphoma.

1987 • 30 citations

Diversity in the available repertoire of murine antibodies reactive with bromelain-treated isologous erythrocytes.

1989 • 27 citations

Polymerization of secretory IgM in B lymphocytes is prevented by a prior targeting to a degradation pathway.

1992 • 26 citations

Differential glycosylation of polymeric and monomeric IGM

1989 • 24 citations

Structural Studies of Human J Chain

1972 • 21 citations

Synthesis but not secretion of J chain by variant mouse myeloma cells which lose alpha-chain-synthesizing ability.

1975 • 19 citations

[40] Biosynthesis, processing, and function of secretory component

1983 • 17 citations

Mutations of the mouse mu H chain which prevent polymer assembly.

1989 • 15 citations

Synthesis but not Secretion of J Chain by Variant Mouse Myeloma Cells Which Lose α-Chain-Synthesizing Ability

1975 • 9 citations

Identification of mouse J chain in human IgM produced by an electrofusion-derived mouse-human heterohybridoma.

1988 • 8 citations