The apoptotic suppressor P35 is required early during baculovirus replication and is targeted to the cytosol of infected cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

1992 • 2,906 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

The establishment of two cell lines from the insectspodoptera frugiperda (lepidoptera; noctuidae)

1977 • 1,219 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1993 • 1,049 citations

Molecular regulation of apoptosis: Genetic controls on cell death

1993 • 923 citations

Prevention of Apoptosis by a Baculovirus Gene During Infection of Insect Cells

1991 • 810 citations

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins.

1992 • 665 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.

1993 • 602 citations

Established Insect Cell Line from the Cabbage Looper, Trichoplusia ni

1970 • 598 citations

Baculovirus Diversity and Molecular Biology

1990 • 540 citations

Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis

1991 • 525 citations

Baculoviruses as Gene Expression Vectors

1988 • 497 citations

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

1993 • 495 citations

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.

1992 • 396 citations

The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

1992 • 354 citations

[33] High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors

1991 • 350 citations

Isolation of genotypic variants of Autographa californica nuclear polyhedrosis virus

1978 • 313 citations

Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus

1993 • 284 citations

Location, sequence, transcriptional mapping, and temporal expression of the gp64 envelope glycoprotein gene of the Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus

1989 • 204 citations

Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans.

1994 • 204 citations

Identification and sequence analysis of a gene encoding gp67, an abundant envelope glycoprotein of the baculovirus Autographa californica nuclear polyhedrosis virus

1989 • 195 citations

Expression of the Baculovirus p35 Gene Inhibits Mammalian Neural Cell Death

1993 • 194 citations

Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex

1987 • 183 citations

Baculovirus structural proteins

1992 • 179 citations

Eight base pairs encompassing the transcriptional start point are the major determinant for baculovirus polyhedrin gene expression

1988 • 170 citations

Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells.

1992 • 169 citations

Site-specific mutagenesis of the 35-kilodalton protein gene encoded by Autographa californica nuclear polyhedrosis virus: cell line-specific effects on virus replication

1992 • 165 citations

Identifying the RNA Polymerases that Synthesize Specific Transcripts of the Autographa Californica Nuclear Polyhedrosis Virus

1990 • 160 citations

Monoclonal antibodies to baculovirus structural proteins: Determination of specificities by western blot analysis

1983 • 156 citations

Identification and characterization of the p35 gene of Bombyx mori nuclear polyhedrosis virus that prevents virus-induced apoptosis

1993 • 155 citations

Molecular analysis of the transcriptional regulatory region of an early baculovirus gene

1989 • 152 citations

Temporal regulation of baculovirus RNA: overlapping early and late transcripts

1985 • 142 citations

Divergent transcription of early 35- and 94-kilodalton protein genes encoded by the HindIII K genome fragment of the baculovirus Autographa californica nuclear polyhedrosis virus

1987 • 138 citations

Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein.

1990 • 132 citations

The hr5 transcriptional enhancer stimulates early expression from the Autographa californica nuclear polyhedrosis virus genome but is not required for virus replication

1993 • 125 citations

Baculovirus transcription in the presence of inhibitors and in nonpermissive Drosophila cells

1986 • 113 citations

Neutralization of budded Autographa californica NPV by a monoclonal antibody: Identification of the target antigen

1984 • 100 citations

Phenotypic characterization and physical mapping of a temperature-sensitive mutant of autographa californica nuclear polyhedrosis virus defective in DNA synthesis

1984 • 91 citations

Specific disruption of intermediate filaments and the nuclear lamina by the 19-kDa product of the adenovirus E1B oncogene.

1989 • 84 citations

Identification of upstream promoter elements mediating early transcription from the 35,000-molecular-weight protein gene of Autographa californica nuclear polyhedrosis virus

1991 • 80 citations

Role of Adenovirus E1B Proteins in Transformation: Altered Organization of Intermediate Filaments in Transformed Cells That Express the 19-Kilodalton Protein

1990 • 60 citations

Enhancement of polyhedrin nuclear localization during baculovirus infection

1992 • 43 citations

Characterization of N- and O-linked oligosaccharides of glycoprotein 350 from Epstein-Barr virus

1989 • 28 citations

The 35-kilodalton protein gene (p35) ofAutographa californicanuclear polyhedrosis virus and the neomycin resistance gene provide dominant selection of recombinant baculoviruses

1993 • 28 citations

Nuclear F-actin: a functional component of baculovirus-infected lepidopteran cells?

1992 • 25 citations