The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 1,618 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Characterization of Herpes Simplex Virus Strains Differing in their Effects on Social Behaviour of Infected Cells

1968 • 874 citations

Programmed cell death: Apoptosis and oncogenesis

1991 • 856 citations

Mapping of Herpes Simplex Virus-1 Neurovirulence to γ ₁ 34.5, a Gene Nonessential for Growth in Culture

1990 • 705 citations

IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells.

1986 • 380 citations

Inverted Repetitions in the Chromosome of Herpes Simplex Virus

1974 • 357 citations

Herpes simplex virus virion host shutoff function

1988 • 350 citations

Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants

1978 • 339 citations

Proteins Specified by Herpes Simplex Virus XI. Identification and Relative Molar Rates of Synthesis of Structural and Nonstructural Herpes Virus Polypeptides in the Infected Cell

1973 • 317 citations

Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

1983 • 293 citations

Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions

1975 • 265 citations

Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA

1982 • 225 citations

Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions

1980 • 185 citations

Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies

1984 • 184 citations

Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants

1990 • 182 citations

The promoter, transcriptional unit, and coding sequence of herpes simplex virus 1 family 35 proteins are contained within and in frame with the UL26 open reading frame

1991 • 152 citations

The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component

1986 • 149 citations

Ocular disease pattern induced by herpes simplex virus is genetically determined by a specific region of viral DNA.

1982 • 131 citations

The herpes simplex virus 1 gene for ICP34.5, which maps in inverted repeats, is conserved in several limited-passage isolates but not in strain 17syn+

1990 • 129 citations

A simple and fast method to extract RNA from tissue culture cells.

1990 • 88 citations

Sequence of MyD116 cDNA: a novel myeloid differentiation primary response gene induced by IL6

1990 • 88 citations

Identification by antibody to a synthetic peptide of a protein specified by a diploid gene located in the terminal repeats of the L component of herpes simplex virus genome

1986 • 81 citations

In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus

1991 • 71 citations

Death of serum-free mouse embryo cells caused by epidermal growth factor deprivation.

1991 • 68 citations

Herpes simplex virus neurovirulence and productive infection of neural cells is associated with a function which maps between 0.82 and 0.832 map units on the hsv genome

1989 • 58 citations

Why do neurons die when deprived of trophic factor?

1989 • 57 citations

The Herpes Simplex Virus Type 2 (HG52) Variant JH2604 Has a 1488 bp Deletion which Eliminates Neurovirulence in Mice

1989 • 56 citations

Genetic and biological analyses of a herpes simplex virus intertypic recombinant reduced specifically for neurovirulence

1987 • 49 citations

Herpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNA

1991 • 48 citations