α-Glycosylceramides Enhance the Antitumor Cytotoxicity of Hepatic Lymphocytes Obtained from Cancer Patients by Activating CD3−CD56+ NK Cells In Vitro

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor.

1994 • 1,079 citations

CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution

1998 • 649 citations

The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

1999 • 624 citations

Requirements for CD1d Recognition by Human Invariant Vα24+ CD4−CD8− T Cells

1997 • 527 citations

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

1998 • 474 citations

An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells.

1994 • 448 citations

CD1d-restricted Recognition of Synthetic Glycolipid Antigens by Human Natural Killer T Cells

1998 • 445 citations

Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes.

1998 • 383 citations

KRN7000, a novel immunomodulator, and its antitumor activities.

1995 • 361 citations

Selective Ability of Mouse CD1 to Present Glycolipids: α-Galactosylceramide Specifically Stimulates Vα14+ NK T Lymphocytes

1998 • 319 citations

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice.

1994 • 304 citations

Mouse NK1+ T cells

1995 • 292 citations

Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells.

1999 • 260 citations

IL-18 Up-Regulates Perforin-Mediated NK Activity Without Increasing Perforin Messenger RNA Expression by Binding to Constitutively Expressed IL-18 Receptor

1999 • 234 citations

CD161 (NKR-P1A) Costimulation of CD1d-dependent Activation of Human T Cells Expressing Invariant Vα24JαQ T Cell Receptor α Chains

1998 • 200 citations

The CD1 family of lipid antigen-presenting molecules

1998 • 171 citations

Treatment of hepatic metastasis of the colon26 adenocarcinoma with an alpha-galactosylceramide, KRN7000.

1998 • 164 citations

Tissue distribution of the non-polymorphic major histocompatibility complex class I-like molecule, CD1d.

1993 • 159 citations

Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12

1999 • 151 citations

Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells.

1998 • 138 citations

A Critical Role for IL-18 in the Proliferation and Activation of NK1.1+CD3− Cells

1998 • 135 citations

Cutting Edge: Structural Requirements for Galactosylceramide Recognition by CD1-Restricted NK T Cells

1998 • 121 citations

Activation of human Vα24NKT cells by α-glycosylceramide in a CD1d-restricted and Vα24TCR-mediated manner

1999 • 92 citations

CD8+NKR-P1A+ T cells preferentially accumulate in human liver

1999 • 75 citations

Human T cells expressing an invariant Va24-JotQ TCRα are CD4- and heterogeneous with respect to TCRβ expression

1996 • 74 citations

Tolerance of NK and LAK activity for HLA class I-deficient targets in a TAP1-deficient patient (bare lymphocyte syndrome type I)

1999 • 68 citations

A novel recognition motif of human NKT antigen receptor for a glycolipid ligand

1999 • 67 citations

Natural killer activity of human liver-derived lymphocytes in various liver diseases

1991 • 64 citations

Enhancing effects of α-, β-monoglycosylceramides on natural killer cell activity

1996 • 54 citations

Enhancing effects of (2S,3S,4R)-1-O-(alpha-D-galactopyranosyl)-2-(N-hexacosanoylamino) -1,3,4-octadecanetriol (KRN7000) on antigen-presenting function of antigen-presenting cells and antimetastatic activity of KRN7000-pretreated antigen-presenting cells.

1996 • 54 citations

Syntheses of Biotinylated α-Galactosylceramides and Their Effects on the Immune System and CD1 Molecules

1999 • 52 citations

Antitumor activity of alpha-galactosylceramide, KRN7000, in mice with EL-4 hepatic metastasis and its cytokine production.

1998 • 49 citations

Antitumor activities of combined treatment with a novel immunomodulator, (2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-2-(N-Hexacosanoylamino)-1,3,4 - octadecanetriol (KRN7000), and radiotherapy in tumor-bearing mice.

1996 • 23 citations

Enhancing Effects of Agelasphin-11 on Natural Killer Cell Activities of Normal and Tumor-Bearing Mice.

1996 • 13 citations

The role of calcium homeostasis and flux during bacterial antigen processing in murine macrophages

1999 • 9 citations

Ceramide derivatives for therapeutic agents

1998 • 8 citations