Ca2+ Oscillations Induced by Hormonal Stimulation of Individual Fura-2-loaded Hepatocytes

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Localization of mitochondria in living cells with rhodamine 123.

1980 • 1,529 citations

[4] Isolation and use of liver cells

1978 • 1,230 citations

Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes

1986 • 790 citations

Fluorescent Probes of Cell Signaling

1989 • 649 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

The second messenger linking receptor activation to internal Ca release in liver

1984 • 557 citations

Calcium Rises Abruptly and Briefly Throughout the Cell at the Onset of Anaphase

1986 • 541 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

"Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells?

1988 • 451 citations

Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells.

1987 • 424 citations

Molecular model for receptor-stimulated calcium spiking.

1988 • 416 citations

Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells

1988 • 412 citations

Changes in free cytosolic Ca2+ in hepatocytes following alpha 1-adrenergic stimulation. Studies on Quin-2-loaded hepatocytes.

1983 • 375 citations

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

1984 • 358 citations

A Ca2+-insensitive form of fura-2 associated with polymorphonuclear leukocytes. Assessment and accurate Ca2+ measurement.

1987 • 317 citations

Spatial and temporal aspects of cell signalling

1988 • 278 citations

Agonist-induced oscillations in cytoplasmic free calcium concentration in single rat hepatocytes

1987 • 271 citations

Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets.

1987 • 231 citations

Studies on Ca channels in intact cardiac cells: voltage-dependent effects and cooperative interactions of dihydropyridine enantiomers.

1986 • 217 citations

Stimulation of inositol trisphosphate formation in hepatocytes by vasopressin, adrenaline and angiotensin II and its relationship to changes in cytosolic free Ca2+

1985 • 212 citations

Hormonal and ionic control of the glycogenolytic cascade in rat liver

1977 • 198 citations

The role of calcium ions in the mechanism of action of α-adrenergic agonists in rat liver

1984 • 183 citations

Oscillations of free cytosolic calcium evoked by cholinergic and catecholaminergic agonists in rat parotid acinar cells.

1988 • 147 citations

Role of membrane potential in the regulation of lectin‐induced calcium uptake

1984 • 121 citations

The role of extracellular Ca2+ in the response of the hepatocyte to Ca2+-dependent hormones.

1985 • 117 citations

Agonist-stimulated oscillations and cycling of intracellular free calcium in individual cultured muscle cells.

1988 • 105 citations

Estimation of intramitochondrial pCa and pH by fura-2 and 2,7 biscarboxyethyl-5(6)-carboxyfluorescein (BCECF) fluorescence

1987 • 96 citations

Calcium oscillations in non-excitable cells

1989 • 94 citations

Novel kinetics of single cell Ca2+ transients in stimulated hepatocytes and A10 cells measured using fura-2 and fluorescent videomicroscopy.

1988 • 93 citations

Agonist-induced Calcium Oscillations in Depolarized Fibroblasts and Their Manipulation by Photoreleased Ins(l,4,5)P3, and Ca++, and Ca++ Buffer

1988 • 89 citations

Calcium Regulation in Biological Systems

1985 • 82 citations

Conversion of esterified fura-2 and indo-1 to Ca2+-sensitive forms by mitochondria

1988 • 77 citations

Intracellular calcium

1984 • 74 citations

Internal perfusion of guinea‐pig hepatocytes with buffered Ca²⁺ or inositol 1,4,5‐trisphosphate mimics noradrenaline activation of K⁺ and Cl⁻ conductances

1987 • 63 citations

Calcium channel agonist and antagonist effects of the stereoisomers of the dihydropyridine 202–791

1985 • 56 citations

Free energy coupling in the interactions between Ca2+, calmodulin, and phosphorylase kinase.

1983 • 53 citations

Heterogeneity of lymphocyte calcium metabolism is caused by T cell-specific calcium-sensitive potassium channel and sensitivity of the calcium ATPase pump to membrane potential.

1988 • 51 citations

Hormone-induced increase in free cytosolic calcium and glycogen phosphorylase activation in rat hepatocytes incubated in normal and low-calcium media

1985 • 48 citations

Incomplete hydrolysis of the calcium indicator precursor fura-2 pentaacetoxymethyl ester (fura-2 AM) by cells

1988 • 45 citations

Sustained oscillations in extracellular calcium concentrations upon hormonal stimulation of perfused rat liver

1987 • 40 citations

Signal Transduction in Mitogenesis: Further Evidence for Multiple Pathways

1988 • 35 citations

Exposure to depolarizing concentrations of K+ inhibits hormonally-induced calcium influx in rat liver

1988 • 16 citations

Microelectrode measurement of cell membrane potential in isolated hepatocytes attached to collagen

1986 • 10 citations