Akt Is a Downstream Target of NF-κB

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

1997 • 2,442 citations

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

1999 • 2,147 citations

NF-κB is a target of AKT in anti-apoptotic PDGF signalling

1999 • 1,830 citations

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

2001 • 1,789 citations

NF-κB Controls Cell Growth and Differentiation through Transcriptional Regulation of Cyclin D1

1999 • 1,282 citations

Ten years of protein kinase B signalling: a hard Akt to follow

2001 • 1,159 citations

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 • 1,129 citations

Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

1995 • 923 citations

Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene

2001 • 908 citations

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1993 • 886 citations

The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB

1999 • 882 citations

Induction of NF-κB by the Akt/PKB kinase

1999 • 847 citations

NF-κB Function in Growth Control: Regulation of Cyclin D1 Expression and G₀/G₁-to-S-Phase Transition

1999 • 777 citations

Activation of Phosphatidylinositol 3-Kinase in Response to Interleukin-1 Leads to Phosphorylation and Activation of the NF-κB p65/RelA Subunit

1999 • 650 citations

Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB

2000 • 637 citations

PKB/AKT: functional insights from genetic models

2001 • 611 citations

Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells.

1996 • 604 citations

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter.

1990 • 263 citations

Nerve Growth Factor-Dependent Activation of NF-κB Contributes to Survival of Sympathetic Neurons

1998 • 225 citations

Nuclear factor-κB, cancer, and apoptosis

2000 • 210 citations

A Phosphatidylinositol 3-Kinase/Akt Pathway, Activated by Tumor Necrosis Factor or Interleukin-1, Inhibits Apoptosis but Does Not Activate NFκB in Human Endothelial Cells

2000 • 209 citations

Interferon α/β Promotes Cell Survival by Activating Nuclear Factor κB through Phosphatidylinositol 3-Kinase and Akt

2001 • 197 citations

Phosphatidylinositol 3-Kinase as a Mediator of TNF-Induced NF-κB Activation

2000 • 176 citations

Activation of NF-κB by Bradykinin through a Gαq- and Gβγ-dependent Pathway That Involves Phosphoinositide 3-Kinase and Akt

2000 • 138 citations

PI3-K/AKT Regulation of NF-κB Signaling Events in Suppression of TNF-Induced Apoptosis

2000 • 121 citations

Regulation of IκBβ in WEHI 231 Mature B Cells

1997 • 74 citations

Structure and Mechanism in NF- B/I B Signaling

1999 • 71 citations

Internalin B Activates Nuclear Factor-κB via Ras, Phosphoinositide 3-Kinase, and Akt

2001 • 63 citations

PDGF‐induced Akt phosphorylation does not activate NF‐κB in human vascular smooth muscle cells and fibroblasts

2000 • 51 citations

Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons

2001 • 41 citations