Adult Bipolar Disorder is Continuous with Pediatric Bipolar Disorder

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States

1994 • 12,456 citations

Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication

2005 • 11,405 citations

Subgenual prefrontal cortex abnormalities in mood disorders

1997 • 2,646 citations

Glial reduction in the subgenual prefrontal cortex in mood disorders

1998 • 1,497 citations

The National Depressive and Manic-depressive Association (DMDA) survey of bipolar members

1994 • 909 citations

Long-Term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (STEP-BD)

2004 • 841 citations

Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells

2000 • 810 citations

The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings

2004 • 791 citations

Bipolar Disorders in a Community Sample of Older Adolescents: Prevalence, Phenomenology, Comorbidity, and Course

1995 • 776 citations

The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases

2002 • 751 citations

Defining Clinical Phenotypes of Juvenile Mania

2003 • 698 citations

Family, twin, and adoption studies of bipolar disorder

2003 • 677 citations

Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation

2003 • 642 citations

Brain Magnetic Resonance Imaging of Structural Abnormalities in Bipolar Disorder

1999 • 628 citations

Clinical Course of Children and Adolescents With Bipolar Spectrum Disorders

2006 • 626 citations

The Brain-Derived Neurotrophic Factor Gene Confers Susceptibility to Bipolar Disorder: Evidence from a Family-Based Association Study

2002 • 604 citations

Amygdala Response to Fearful Faces in Anxious and Depressed Children

2001 • 583 citations

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus

2002 • 570 citations

Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder

2001 • 568 citations

Efficacy of Olanzapine in Acute Bipolar Mania<subtitle>A Double-blind, Placebo-Controlled Study</subtitle>

2000 • 557 citations

Double-Blind and Placebo-Controlled Study of Lithium for Adolescent Bipolar Disorders With Secondary Substance Dependency

1998 • 519 citations

Critical role of brain-derived neurotrophic factor in mood disorders

2004 • 504 citations

A Functional Magnetic Resonance Imaging Study of Bipolar Disorder

2003 • 472 citations

Prevalence, Clinical Correlates, and Longitudinal Course of Severe Mood Dysregulation in Children

2006 • 467 citations

Neuroimaging Studies of Amygdala Function in Anxiety Disorders

2003 • 453 citations

Four-Year Prospective Outcome and Natural History of Mania in ChildrenWith a Prepubertal and Early Adolescent Bipolar Disorder Phenotype

2004 • 445 citations

Early physical and sexual abuse associated with an adverse course of bipolar illness

2002 • 396 citations

Amygdala and Hippocampal Volumes in Adolescents and Adults With Bipolar Disorder

2003 • 390 citations

Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder

1997 • 358 citations

fMRI during affect discrimination in bipolar affective disorder

2000 • 358 citations

Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic–depressive illness

2000 • 352 citations

Obsessive-Compulsive and Spectrum Disorders in Children and Adolescents

2006 • 349 citations

Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder

2004 • 347 citations

Pediatric Bipolar Disorder: A Review of the Past 10 Years

2005 • 347 citations

Factors Associated With Suicide Attempts in 648 Patients With Bipolar Disorder in the Stanley Foundation Bipolar Network

2003 • 345 citations

A family study of bipolar I disorder in adolescence

1988 • 341 citations

Rapid, continuous cycling and psychiatric co‐morbidity in pediatric bipolar I disorder

2001 • 324 citations

Attention-Deficit Hyperactivity Disorder With Bipolar Disorder: A Familial Subtype?

1997 • 314 citations

Bipolar disorder during adolescence and young adulthood in a community sample

2000 • 304 citations

Review of studies of child and adolescent offspring of bipolar parents

2001 • 297 citations

Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder

2000 • 291 citations

Anomalous Prefrontal-Subcortical Activation in Familial Pediatric BipolarDisorder

2004 • 285 citations

Regional prefrontal gray and white matter abnormalities in bipolar disorder

2002 • 279 citations

Diagnostic Characteristics of 93 Cases of a Prepubertal and Early Adolescent Bipolar Disorder Phenotype by Gender, Puberty and Comorbid Attention Deficit Hyperactivity Disorder

2000 • 260 citations

Frontotemporal Alterations in Pediatric Bipolar Disorder

2005 • 253 citations

Reduced Amygdalar Gray Matter Volume in Familial Pediatric Bipolar Disorder

2005 • 251 citations

Phenomenology of Prepubertal and Early Adolescent Bipolar Disorder: Examples of Elated Mood, Grandiose Behaviors, Decreased Need for Sleep, Racing Thoughts and Hypersexuality

2002 • 247 citations

A Preliminary fMRI Study of Sustained Attention in Euthymic, Unmedicated Bipolar Disorder

2004 • 243 citations

Frontostriatal Abnormalities in Adolescents With Bipolar Disorder: Preliminary Observations From Functional MRI

2003 • 235 citations

Pediatric mania: a developmental subtype of bipolar disorder?

2000 • 235 citations

Early age at onset as a risk factor for poor outcome of bipolar disorder

2003 • 233 citations

Association Study of a Brain-Derived Neurotrophic-Factor Genetic Polymorphism and Mood Disorders, Age of Onset and Suicidal Behavior

2003 • 224 citations

A Double-Blind, Randomized, Placebo-Controlled Trial of Oxcarbazepine in the Treatment of Bipolar Disorder in Children and Adolescents

2006 • 197 citations

Linkage Disequilibrium of the Brain-Derived Neurotrophic Factor Val66Met Polymorphism in Children With a Prepubertal and Early Adolescent Bipolar Disorder Phenotype

2004 • 190 citations

Voxel-based morphometry in adolescents with bipolar disorder: first results

2004 • 189 citations

A Double-Blind Randomized Pilot Study Comparing Quetiapine and Divalproex for Adolescent Mania

2006 • 189 citations

Topiramate monotherapy in the management of acute mania: results of four double‐blind placebo‐controlled trials

2006 • 182 citations

A plea for integrity of the bipolar disorder concept

2000 • 164 citations

Cross-sectional study of abnormal amygdala development in adolescents and young adults with bipolar disorder

2004 • 162 citations

Does Lithium Treatment Still Work?

2000 • 161 citations

Decreased N-Acetylaspartate in children with familial bipolar disorder

2003 • 160 citations

Open-Label, 8-Week Trial of Olanzapine and Risperidone for the Treatment of Bipolar Disorder in Preschool-Age Children

2005 • 151 citations

An Open-Label Trial of Divalproex in Children and Adolescents With Bipolar Disorder

2002 • 144 citations

An overview of recent findings of the Stanley Foundation Bipolar Network (Part I)

2003 • 143 citations

Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder

2003 • 142 citations

An Open-Label Study of Lamotrigine Adjunct or Monotherapy for the Treatment of Adolescents With Bipolar Depression

2006 • 139 citations

A Pilot Controlled Trial of Topiramate for Mania in Children and Adolescents With Bipolar Disorder

2005 • 138 citations

“Multidimensionally Impaired Disorder”: Is It a Variant of Very Early-Onset Schizophrenia?

1998 • 128 citations

A prepubertal and early adolescent bipolar disorder‐I phenotype: review of phenomenology and longitudinal course

2003 • 127 citations

Cortical gray matter differences identified by structural magnetic resonance imaging in pediatric bipolar disorder

2005 • 119 citations

Cortical Magnetic Resonance Imaging Findings in Familial Pediatric Bipolar Disorder

2005 • 119 citations

Cortical gray matter deficit in patients with bipolar disorder

1999 • 112 citations

How Cardinal are Cardinal Symptoms in Pediatric Bipolar Disorder? An Examination of Clinical Correlates

2005 • 108 citations

Reduced NAA Levels in the Dorsolateral Prefrontal Cortex of Young Bipolar Patients

2005 • 102 citations

No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: A multicenter study

2004 • 100 citations

Association analysis of brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder

2004 • 100 citations

Increased Prevalence and Earlier Onset of Mood Disorders Among Relatives of Prepubertal Versus Adult Probands

1997 • 99 citations

An Open-Label Trial of Risperidone in Children and Adolescents with Bipolar Disorder

2005 • 85 citations

Methodological Issues and Controversies in Clinical Trials with Child and Adolescent Patients with Bipolar Disorder: Report of a Consensus Conference

2003 • 81 citations

Three Potential Susceptibility Loci Shown by a Genome-Wide Scan for Regions Influencing the Age at Onset of Mania

2004 • 76 citations

Early Onset Bipolar Disorder: Clinical and Research Considerations

2005 • 76 citations

Family, twin, adoption, and molecular genetic studies of juvenile bipolar disorder

2005 • 75 citations

Definitions of Rapid, Ultrarapid, and Ultradian Cycling and of Episode Duration in Pediatric and Adult Bipolar Disorders: A Proposal to Distinguish Episodes from Cycles

2003 • 74 citations

Bipolar offspring

2003 • 73 citations

Prepubertal and early adolescent bipolar I disorder: review of diagnostic validation by Robins and Guze criteria.

2005 • 63 citations

Clinical characteristics of bipolar disorder in very young children

2006 • 44 citations

Bipolar Disorder in Childhood and Early Adolescence

2004 • 39 citations

Delayed Diagnosis of Pediatric Bipolar Disorder in a Community Mental Health Setting

2006 • 38 citations

Early onset bipolar disorder: possible linkage to chromosome 9q34

2006 • 35 citations

Special issues in the treatment of paediatric bipolar disorder

2001 • 29 citations

Anticonvulsants in the treatment of bipolar mania

2006 • 26 citations

Multidimensionally Impaired: The Good News

2005 • 16 citations