Family, twin, and adoption studies of bipolar disorder

Research Diagnostic Criteria

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Diagnostic Criteria for Use in Psychiatric Research

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Diagnostic and Statistical Manual of Mental Disorders, 5th Edition

2013 • 4,493 citations

MANIC DEPRESSIVE ILLNESS

1984 • 3,013 citations

Cross-National Epidemiology of Major Depression and Bipolar Disorder

1996 • 2,176 citations

A Family Study of Schizoaffective, Bipolar I, Bipolar II, Unipolar, and Normal Control Probands

1982 • 995 citations

Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

2002 • 824 citations

Heritability Estimates for Psychotic Disorders

1999 • 779 citations

The epidemiology of DSM-III-R bipolar I disorder in a general population survey

1997 • 615 citations

Psychiatric Disorders in the Biological and Adoptive Families of Adopted Individuals With Affective Disorders

1986 • 556 citations

The Family History Approach to Diagnosis

1986 • 537 citations

A Danish Twin Study of Manic-Depressive Disorders

1977 • 501 citations

Psychiatric Disorders in the Relatives of Probands With Affective Disorders

1984 • 494 citations

Aufteilung der endogenen Psychosen

1957 • 492 citations

A Twin Study of Genetic Relationships Between Psychotic Symptoms

2002 • 460 citations

Morbidity Risks of Schizophrenia and Affective Disorders among First Degree Relatives of Patients with Schizophrenia, Mania, Depression and Surgical Conditions

1980 • 432 citations

Twin Studies of Psychiatric Illness

2001 • 383 citations

Continuity and Discontinuity of Affective Disorders and Schizophrenia

1993 • 379 citations

Adoption study supporting genetic transmission in manic–depressive illness

1977 • 376 citations

Is Response to Prophylactic Lithium a Familial Trait?

2002 • 374 citations

The Familial Transmission of Bipolar Illness

1987 • 366 citations

The genetics of mood disorders

1990 • 349 citations

A Controlled Family Study of Chronic Psychoses

1988 • 347 citations

A family study of bipolar I disorder in adolescence

1988 • 341 citations

Early and late onset bipolar disorders: two different forms of manic-depressive illness?

2000 • 285 citations

Bipolarity from ancient to modern times:

2001 • 256 citations

Bipolar II

1985 • 221 citations

Twin Studies of Psychiatric Illness

1993 • 219 citations

A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses. Introduction.

1966 • 219 citations

Familial Rates of Affective Disorder

1987 • 215 citations

Genetic Factors in Moderately Severe and Mild Affective Disorders

1986 • 193 citations

Mapping susceptibility genes for bipolar disorder: a pharmacogenetic approach based on excellent response to lithium

2001 • 169 citations

A plea for integrity of the bipolar disorder concept

2000 • 164 citations

Relationship Between the Effectiveness of Lithium Therapy and Family History

1973 • 164 citations

Comorbid Bipolar Disorder and Panic Disorder in Families With a High Prevalence of Bipolar Disorder

2002 • 163 citations

Catechol O-Methyltransferase, Serotonin Transporter, and Tryptophan Hydroxylase Gene Polymorphisms in Bipolar Disorder Patients With and Without Comorbid Panic Disorder

2002 • 161 citations

The course of development of mania in patients with recurrent depression

1976 • 161 citations

Lithium response and genetics of affective disorders

1994 • 159 citations

The risk for psychiatric disorders in relatives of schizophrenic and control probands: a comparison of three independent studies

1997 • 158 citations

The Familial Aggregation of Psychotic Symptoms in Bipolar Disorder Pedigrees

2001 • 158 citations

Diagnostic Reliability of Bipolar II Disorder

2002 • 153 citations

A Family Study of Bipolar II Disorder

1984 • 150 citations

Transmitted factors in the morbid risk of affective disorders: A controlled study

1975 • 148 citations

The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: results of a controlled family study

1993 • 147 citations

Contested boundaries of bipolar disorder and the limits of categorical diagnosis in psychiatry

1992 • 143 citations

Bipolar disorder and panic disorder in families: an analysis of chromosome 18 data.

1998 • 143 citations

A Pilot Swedish Twin Study of Affective Illness, Including Hospital- and Population-Ascertained Subsamples

1993 • 139 citations

A pilot Swedish twin study of affective illness including hospital- and population-ascertained subsamples: Results of model fitting

1995 • 132 citations

Panic disorder with familial bipolar disorder

1997 • 118 citations

Bipolar manic-depressive psychoses: Results of a genetic investigation

1980 • 116 citations

Increased morbid risk for schizophrenia in families of in-patients with bipolar illness

2000 • 106 citations

Bipolar II: the most common bipolar phenotype?

1993 • 105 citations

The Genetics of Mood Disorders

1991 • 101 citations

A Family Study of Manic-Depressive (Bipolar I) Disease

1995 • 93 citations

A Family Interview Study of Male Manic Depressives

1974 • 88 citations

A genetic study of affective disorders

1977 • 87 citations

A Genetic Study of Bipolar Affective Disorder

1975 • 85 citations

Morbidity risk and genetic transmission in manic-depressive illness.

1974 • 85 citations

Risks of Affective Illness Among First-Degree Relatives of Bipolar I Old-Order Amish Probands

1992 • 83 citations

Different familial transmission patterns in bipolar I disorder with onset before and after age 25

2001 • 82 citations

Molecular linkage studies of bipolar disorders

2001 • 78 citations

Are schizophrenia and affective disorder related? preliminary data from a family study

1993 • 75 citations

Analysis of Familial Factors in Bipolar Affective Illness

1977 • 75 citations

Parsing pediatric bipolar disorder from its associated comorbidity with the disruptive behavior disorders

2001 • 75 citations

Early- and Late-Onset Bipolar Illness

1981 • 73 citations

Outcomes on lithium treatment as a tool for genetic studies in affective disorders

1984 • 72 citations

Familial aggregation of psychotic symptoms in a replication set of 69 bipolar disorder pedigrees

2002 • 67 citations

A comparison of unipolar and bipolar depressive illness

1980 • 64 citations

Do puerperal psychotic episodes identify a more familial subtype of bipolar disorder? Results of a family history study

2002 • 60 citations

Mode of inheritance in families of patients with lithium‐responsive affective disorders

1994 • 55 citations

Genetic Counselling for Schizophrenia in the Era of Molecular Genetics

2001 • 55 citations

Sibling pairs with affective disorders: resemblance of demographic and clinical features

2002 • 54 citations

Unipolar relatives in bipolar pedigrees

1993 • 51 citations

Unipolar relatives in bipolar pedigrees: A search for elusive indicators of underlying bipolarity

1996 • 49 citations

Manic-depressive illness. A clinical, social and genetic study.

1977 • 48 citations

Early- and Late-Onset Bipolar Affective Disorder

1977 • 43 citations

Twin Studies of Psychiatric Illness

2001 • 42 citations

Introduction

1966 • 40 citations

Family history and symptom levels during treatment for bipolar I affective disorder

2000 • 38 citations

Autosomal recessive inheritance of affective disorders in families of responders to lithium prophylaxis?

1997 • 37 citations

How do children learn the meanings of verbs?

1977 • 37 citations

A family study of early-onset bipolar I disorder

2002 • 36 citations

Relationship between prophylactic effect of lithium therapy and family history of affective disorders

1997 • 31 citations

Sex differences in affective disorder: Genetic transmission

1987 • 27 citations

Genetic counseling for psychiatric disorders

2001 • 24 citations

Washington University: Adult Psychiatry

1997 • 16 citations

Genetical Analysis of Unipolar and Bipolar Endogenous Affective Psychoses

1977 • 15 citations

Genetics of early onset bipolar affective disorder: Are we making progress?

2002 • 10 citations