Characterization of the Molecular Defect in Factor VR506A

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Mutation in blood coagulation factor V associated with resistance to activated protein C

1994 • 3,871 citations

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

1993 • 1,997 citations

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

1993 • 1,283 citations

A simple method for the preparation of homogeneous phospholipid vesicles

1977 • 861 citations

COFACTOR PROTEINS IN THE ASSEMBLY AND EXPRESSION OF BLOOD CLOTTING ENZYME COMPLEXES

1988 • 535 citations

Human Plasma Protein C

1979 • 511 citations

Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V

1994 • 446 citations

Complete cDNA and derived amino acid sequence of human factor V.

1987 • 416 citations

The mechanism of inactivation of human factor V and human factor Va by activated protein C.

1994 • 413 citations

Anticoagulant protein C pathway defective in majority of thrombophilic patients [see comments]

1993 • 411 citations

Inactivation of human coagulation factor V by activated protein C.

1983 • 374 citations

Inherited resistance to activated protein C iscorrected by anticoagulant cofactor activity found to be a property of factorV.

1994 • 359 citations

Anticoagulant protein C pathway defective in majority of thrombophilic patients [see comments]

1993 • 337 citations

Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa.

1994 • 307 citations

A model for the tissue factor pathway to thrombin. I. An empirical study.

1994 • 242 citations

[14] Thrombin

1976 • 214 citations

Interactions of a fluorescent active-site-directed inhibitor of thrombin: dansylarginine N-(3-ethyl-1,5-pentanediyl)amide

1979 • 213 citations

Isolation of functional human coagulation factor V by using a hybridoma antibody.

1981 • 208 citations

Simultaneous Purification of Bovine Prothrombin and Factor X

1973 • 204 citations

Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin.

1986 • 187 citations

The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects

1994 • 170 citations

Kinetics of inactivation of membrane-bound factor Va by activated protein C. Protein S modulates factor Xa protection.

1988 • 158 citations

Blood coagulation factor Va abnormality associated with resistance to activated protein C in venous thrombophilia

1994 • 129 citations

Role of the membrane in the inactivation of factor Va by activated protein C.

1993 • 99 citations

A conserved epitope on several human vitamin K-dependent proteins. Location of the antigenic site and influence of metal ions on antibody binding.

1988 • 38 citations

[13] Factor V

1993 • 27 citations

Loss of membrane-dependent factor Va cleavage: a mechanistic interpretation of the pathology of protein CVermont

1994 • 12 citations

Heterogeneity of the APC-resistance phenomenon

1994 • 7 citations