Activation of Ada protein as a transcriptional regulator by direct alkylation with methylating agents.

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 • 645 citations

Use of γ-(4-Nitrobenzyl)pyridine as Analytical Reagent for Ethylenimines and Alkylating Agents

1955 • 348 citations

Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents

1982 • 287 citations

Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1982 • 283 citations

The intracellular signal for induction of resistance to alkylating agents in E. coli

1986 • 222 citations

Purification and structure of the intact Ada regulatory protein of Escherichia coli K12, O6-methylguanine-DNA methyltransferase.

1985 • 124 citations

Regulatory mechanisms for induction of synthesis of repair enzymes in response to alkylating agents: ada protein acts as a transcriptional regulator.

1986 • 108 citations

Adaptive response: induced synthesis of DNA repair enzymes by alkylating agents

1987 • 56 citations

Potent induction of the adaptive response by a weak mutagen, methyl iodide, in Escherichia coli☆

1987 • 17 citations

Methyl iodide, a potent inducer of the adaptive response without appreciable mutagenicity in E. coli

1987 • 11 citations