Inactivation of endothelin I by deamidase (lysosomal protective protein).

Eine neue Methode zur Synthese von Peptiden: Aktivierung der Carboxylgruppe mit Dicyclohexylcarbodiimid unter Zusatz von 1‐Hydroxy‐benzotriazolen

1970 • 1,555 citations

Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones ¹

1989 • 552 citations

Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor.

1991 • 360 citations

Carboxypeptidase E

1988 • 308 citations

Enkephalin convertase: purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules.

1982 • 283 citations

The hydrolysis of endothelins by neutral endopeptidase 24.11 (enkephalinase).

1990 • 247 citations

Structure-activity relationships of endothelin: Importance of the C-terminal moiety

1988 • 220 citations

Expression of cDNA encoding the human “protective protein≓ associated with lysosomal β-galactosidase and neuraminidase: Homology to yeast proteases

1988 • 219 citations

A peptidase in human platelets that deamidates tachykinins. Probable identity with the lysosomal "protective protein".

1990 • 165 citations

Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro.

1991 • 165 citations

Human lysosomal protective protein has cathepsin A-like activity distinct from its protective function

1991 • 160 citations

Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme

1990 • 142 citations

ENZYMATIC STUDIES ON BRADYKININ AND SIMILAR PEPTIDES

1963 • 138 citations

Structure-activity relationship of endothelin: Importance of charged groups

1989 • 120 citations

Endothelins are more sensitive than sarafotoxins to neutral endopeptidase: possible physiological significance.

1990 • 118 citations

Membrane-associated cathepsin L: A role in metastasis of melanomas

1989 • 84 citations

Mechanisms of Human Bladder Tumor Invasion: Role of Protease Cathepsin B

1990 • 84 citations

Carboxypeptidase M in Madin-Darby canine kidney cells. Evidence that carboxypeptidase M has a phosphatidylinositol glycan anchor.

1990 • 75 citations

Enkephalin convertase: Potent, selective, and irreversible inhibitors

1983 • 74 citations

Cloning and function expression of human endothelin-1 receptor cDNA

1991 • 72 citations

Endothelins: a family of regulatory peptides. State-of-the-art lecture.

1991 • 65 citations

Endothelin receptors cloned, endothelin converting enzyme characterized and pathophysiological roles for endothelin proposed

1991 • 63 citations

Endothelins and sarafotoxins: physiological regulation, receptor subtypes and transmembrane signaling

1991 • 58 citations

Conversion of big endothelin-1 to endothelin-1 by two-types of metalloproteinases of cultured porcine vascular smooth muscle cells

1991 • 48 citations

Characteristics of an enzyme that inactivates angiotensin II (Angiotensinase C)

1970 • 48 citations

Endothelin converting enzyme of bovine carotid artery smooth muscles

1991 • 47 citations

Phosphoramidon-sensitive endothelin-converting enzyme in the cytosol of cultured bovine endothelial cells

1991 • 43 citations

Metabolism of substance P and bradykinin by human neutrophils

1991 • 40 citations

Evidence for phosphoramidon-sensitive conversion of big endothelin-1 to endothelin-1 in isolated rat mesenteric artery

1991 • 20 citations

Degradation of Bioactive Substances

2024 • 4 citations