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Cytochrome P3-450 cDNA encodes aflatoxin B1-4-hydroxylase.

Data up to Jan 2025

Published1988
Citations53
References31

Total Citations Per Year

Abstract

References (31)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

1987 • 1,559 citations

Multiplicity of mammalian microsomal cytochromes P-45.

1979 • 633 citations

Enzymatic activation of chemicals to toxic metabolites

1985 • 331 citations

Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential.

1976 • 300 citations

Genes for Cytochrome P-450 and Their Regulatio

1986 • 227 citations

The role of aflatoxin metabolism in its toxic lesion

1976 • 212 citations

The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences.

1984 • 199 citations

Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene.

1979 • 166 citations

Correlation of dietary aflatoxin B1 levels with excretion of aflatoxin M1 in human urine.

1987 • 155 citations

Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution

1982 • 145 citations

Inhibition of aflatoxin B1 carcinogenesis in rainbow trout by flavone and indole compounds

1984 • 121 citations

Carcinogenicity of dietary aflatoxin M1 in male Fischer rats compared to aflatoxin B1.

1987 • 109 citations

Aflatoxin M1 in Human Urine

1970 • 103 citations

Structural gene product of the [Ah] complex. Evidence for transcriptional control of cytochrome P1-450 induction by use of a cloned DNA sequence.

1981 • 93 citations

Multifactoral etiology of human liver cancer

1984 • 86 citations

Isolation and characterization of full-length mouse cDNA and genomic clones of 3-methylcholanthrene-inducible cytochrome P1-450 and P3-450

1984 • 76 citations

Effects of inducers and inhibitors on the metabolism of aflatoxin B, by rat and mouse

1979 • 63 citations

Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells.

1987 • 62 citations

Mouse cytochrome P3-450: complete cDNA and amino acid sequence

1984 • 60 citations

Inhibition of aflatoxin B1 -hepatocarcinogenesis in rats by β-naphthoflavone

1985 • 55 citations

Comparative mutagenicity of aflatoxins using a Salmonella/trout hepatic enzyme activation system

1982 • 54 citations

Metabolic activation of aflatoxins related to their mutagenicity

1978 • 52 citations

Association and dissociation of the Ah locus with the metabolism of aflatoxin B1 by mouse liver. Co-segregation of aflatoxin B1 hydroxylase induction with aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction.

1978 • 38 citations

Genetic expression of aflatoxin B1 metabolism: effects of 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the metabolism of aflatoxins B1 and B2 by various inbred strains of mice.

1980 • 25 citations

Hepatic Microsomal Enzyme Induction in Rats Fed Varietal Cauliflower Leaves

1975 • 24 citations

Genetic expression of aflatoxin metabolism

1983 • 17 citations

Differential sensitivity of ah‐responsive mice to β‐naphthoflavone‐induced metabolism and m utagenesis of benzo[a]pyrene and aflatoxin B1

1985 • 8 citations

Genetic dependence of hepatic microsome-mediated depression of aflatoxin B1 activation to mutagens in Ames Salmonella typhimurium TA-98 system

1980 • 8 citations

Aflatoxin B1-4-hydroxylase is associated with cytochrome P3-450 in C57BL6 mouse liver

1987 • 5 citations

Environmental Cancer: Advances in Modern Toxicology, vol 3

1978 • 3 citations

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Cytochrome P3-450 cDNA encodes aflatoxin B1-4-hydroxylase. (1988) – Journal of Biological Chemistry | Metascience Observatory Explorer