Development of muscarinic cholinergic inhibition of adenylate cyclase in embryonic chick heart. Its relationship to changes in the inhibitory guanine nucleotide regulatory protein.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.

1984 • 498 citations

Specific uncoupling by islet-activating protein, pertussis toxin, of negative signal transduction via alpha-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells.

1983 • 493 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes.

1983 • 406 citations

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.

1984 • 345 citations

Reconstitution of resolved muscarinic cholinergic receptors with purified GTP-binding proteins.

1985 • 314 citations

The regulatory components of adenylate cyclase and transducin. A family of structurally homologous guanine nucleotide-binding proteins.

1983 • 304 citations

Guanine nucleotides modulate muscarinic receptor binding in the heart

1979 • 236 citations

Ontogenetic development of autonomic neuroeffector transmission and transmitter reactivity in embryonic and fetal hearts.

1977 • 225 citations

Identification of a gamma subunit associated with the adenylyl cyclase regulatory proteins Ns and Ni.

1984 • 214 citations

Physical and immunological characterization of a guanine nucleotide-binding protein purified from bovine cerebral cortex.

1985 • 205 citations

Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP.

1979 • 200 citations

Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells.

1983 • 187 citations

Inhibition of adenylate cyclase by hormones and neurotransmitters

1979 • 187 citations

GTP-dependent inhibition of cardiac adenylate cyclase by muscarinic cholinergic agonists

1979 • 178 citations

Muscarinic acetylcholine receptors in developing chick heart

1977 • 177 citations

A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes.

1980 • 152 citations

Cardiac muscarinic cholinergic receptor binding is regulated by Na+ and guanyl nucleotides.

1980 • 140 citations

The biphasic response of muscarinic cholinergic receptors in cultured heart cells to agonists. Effects on receptor number and affinity in intact cells and homogenates.

1982 • 108 citations

Ontogenesis of physiological responsiveness and guanine nucleotide sensitivity of cardiac muscarinic receptors during chick embryonic development

1984 • 79 citations

Size and detergent binding of adenylate cyclase from bovine cerebral cortex.

1978 • 59 citations

Heart contains two substrates (Mr = 40,000 and 41,000) for pertussis toxin-catalyzed ADP-ribosylation that co-purify with Ns

1985 • 50 citations

Agonist-induced changes in the modulation of K+ permeability and beating rate by muscarinic agonists in cultured heart cells.

1982 • 41 citations

MEASUREMENT OF THE INOTROPIC EFFECTS OF DRUGS ON THE INNERVATED AND NONINNERVATED EMBRYONIC CHICK HEART

1960 • 38 citations

Non-co-ordinate development of β-adrenergic receptors and adenylate cyclase in chick heart

1982 • 23 citations

The development of physiologic responsiveness to muscarinic agonists in chick embryo heart cell cultures. Role of high affinity receptors and sensitivity to guanine nucleotides.

1984 • 21 citations

Differences in the properties of muscarinic cholinergic receptors in the developing chick myocardium.

1985 • 12 citations

Drug receptors and their effectors

1982 • 6 citations