The development of physiologic responsiveness to muscarinic agonists in chick embryo heart cell cultures. Role of high affinity receptors and sensitivity to guanine nucleotides.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES

1943 • 2,733 citations

Muscarinic Cholinergic Binding in Rat Brain

1974 • 1,214 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

The binding of agonists to brain muscarinic receptors.

1978 • 656 citations

Introduction to Statistical Analysis

1958 • 648 citations

Elevation of Guanosine 3′,5′-Cyclic Phosphate in Rat Heart after Perfusion with Acetylcholine

1970 • 455 citations

Modification by islet-activating protein of receptor-mediated regulation of cyclic AMP accumulation in isolated rat heart cells.

1981 • 326 citations

Regulation of spontaneous activity and growth of embryonic chick heart cells in tissue culture

1967 • 280 citations

Changes in membrane currents in bullfrog atrium produced by acetylcholine.

1976 • 259 citations

Guanine nucleotides modulate muscarinic receptor binding in the heart

1979 • 236 citations

Ontogenetic development of autonomic neuroeffector transmission and transmitter reactivity in embryonic and fetal hearts.

1977 • 225 citations

Muscarinic cholinergic receptor modulation of beta-adrenergic receptor affinity for catecholamines.

1978 • 224 citations

On the mechanism of the negative inotropic effect of acetylcholine

1976 • 218 citations

Inhibition of adenylate cyclase by hormones and neurotransmitters

1979 • 187 citations

Muscarinic acetylcholine receptors in developing chick heart

1977 • 177 citations

A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes.

1980 • 152 citations

Cardiac muscarinic cholinergic receptor binding is regulated by Na+ and guanyl nucleotides.

1980 • 140 citations

Differential modification of the interaction of cardiac muscarinic cholinergic and beta-adrenergic receptors with a guanine nucleotide binding component(s).

1982 • 137 citations

The biphasic response of muscarinic cholinergic receptors in cultured heart cells to agonists. Effects on receptor number and affinity in intact cells and homogenates.

1982 • 108 citations

Effects of cholinergic and adrenergic agonists on phosphorylation of a 165,000-dalton myofibrillar protein in intact cardiac muscle.

1982 • 104 citations

Inotropic effects and changes in sodium and calcium contents associated with inhibition of monovalent cation active transport by ouabain in cultured myocardial cells.

1979 • 104 citations

Agonist and guanine nucleotide modulation of muscarinic cholinergic receptors in cultured heart cells.

1980 • 89 citations

Stimulation of Hydrolysis of Phosphatidic Acid by Cholinergic Agents in Guinea Pig Synaptosomes

1974 • 73 citations

Muscarinic receptor binding in rat brain using the agonist, [3H]cis methyldioxolane

1980 • 70 citations

Ion Levels and Membrane Potential in Chick Heart Tissue and Cultured Cells

1973 • 64 citations

Developmental aspects of potassium flux and permeability of the embryonic chick heart.

1976 • 51 citations

Agonist-induced changes in the modulation of K+ permeability and beating rate by muscarinic agonists in cultured heart cells.

1982 • 41 citations

Release of acetylcholine by chick embryo heart before innervation

1970 • 30 citations

Intracellular potassium and sodium activities of chick ventricular muscle during embryonic development.

1980 • 28 citations

Non-co-ordinate development of β-adrenergic receptors and adenylate cyclase in chick heart

1982 • 23 citations