Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Cationic liposome-mediated transfection

1989 • 974 citations

Theory of self-assembly of lipid bilayers and vesicles

1977 • 903 citations

A novel cationic liposome reagent for efficient transfection of mammalian cells

1991 • 844 citations

Cationic liposome-mediated RNA transfection.

1989 • 804 citations

Systemic Gene Expression After Intravenous DNA Delivery into Adult Mice

1993 • 725 citations

Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.

1989 • 709 citations

Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides.

1992 • 609 citations

Site-Specific Gene Expression in Vivo by Direct Gene Transfer into the Arterial Wall

1990 • 573 citations

Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms.

1991 • 468 citations

Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles

1990 • 424 citations

A new cationic liposome reagent mediating nearly quantitative transfection of animal cells.

1991 • 390 citations

Phosphatodylethanolamine liposomes: drug delivery, gene transfer and immunodiagnostic applications

1992 • 365 citations

Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes.

1992 • 334 citations

Aerosol gene delivery in vivo.

1992 • 271 citations

Interactions of cationic lipid vesicles with negatively charged phospholipid vesicles and biological membranes

1988 • 269 citations

Lipofection of cDNAs in the embryonic vertebrate central nervous system

1990 • 262 citations

Effect of cationic cholesterol derivatives on gene transfer and protein kinase C activity

1992 • 238 citations

Use of a quaternary ammonium detergent in liposome mediated DNA transfection of mouse L-cells

1989 • 211 citations

Rapid Communication: In vivo Transfection of Murine Lungs with a Functioning Prokaryotic Gene using a Liposome Vehicle

1989 • 203 citations

Effect of surface curvature on stability, thermodynamic behavior, and osmotic activity of dipalmitoylphosphatidylcholine single lamellar vesicles

1981 • 192 citations

Inverted micellar intermediates and the transitions between lamellar, cubic, and inverted hexagonal lipid phases. I. Mechanism of the L alpha----HII phase transitions

1986 • 173 citations

Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung afterin vivointratracheal plasmid-mediated gene transfer

1992 • 172 citations

Evidence for specificity in the encapsidation of Sindbis virus RNAs

1989 • 167 citations

Lipophilic polylysines mediate efficient DNA transfection in mammalian cells

1991 • 149 citations

Direct in vivo gene transfer into the coronary and peripheral vasculatures of the intact dog.

1991 • 144 citations

Fusion of liposomes containing a novel cationic lipid, N-[2,3-(dioleyloxy)propyl]-N,N,N-trimethylammonium: induction by multivalent anions and asymmetric fusion with acidic phospholipid vesicles

1989 • 135 citations

In vivo gene delivery. Efficient transfection of T lymphocytes in adult mice

1993 • 129 citations

Plasmid DNAs directly injected into mouse brain with lipofectin can be incorporated and expressed by brain cells

1990 • 124 citations

Persistence of plasmid DNA and expression in rat brain cells in vivo

1992 • 119 citations

Immunotherapy of Malignancy by In Vivo Gene Transfer into Tumors

1992 • 117 citations

Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B.

1991 • 116 citations

Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis.

1992 • 103 citations

Electrostatic interactions at charged lipid membranes. Hydrogen bonds in lipid membrane surfaces

1979 • 97 citations

Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells.

1993 • 95 citations

Regulation of gene expression in vivo by liposome-mediated delivery of a purified transcription factor.

1990 • 91 citations

Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway.

1992 • 90 citations

Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes.

1992 • 84 citations

Efficient Transfection and Expression of Heterologous Genes in PC12 Cells

1990 • 78 citations

Membrane Fusion

1985 • 74 citations

Asymmetric incorporation of trisialoganglioside into dipalmitoylphosphatidylcholine vesicles

1981 • 61 citations

Kinetics of transfer of gangliosides from their micelles to dipalmitoylphosphatidylcholine vesicles

1983 • 48 citations

Expression of a Prokaiyotic Gene in Cultured Lung Endothelial Cells after Lipofection with a Plasmid Vector

1989 • 44 citations

Decreased catalytic subunit mRNA levels and altered catalytic subunit mRNA structure in a cAMP-resistant Chinese hamster ovary cell line

1991 • 33 citations

Transition of a liquid crystalline phosphatidylcholine bilayer to the gel phase in a vesicle reduces the internal aqueous volume

1982 • 27 citations

Gene transfer into intact vertebrate embryos.

1991 • 11 citations