Gelatinases A and B Are Up-Regulated in Rat Lungs by Subacute Hyperoxia

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 • 1,421 citations

Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase

1993 • 1,226 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

The Role of Nuclear Factor- κ B in Cytokine Gene Regulation

1997 • 948 citations

Molecular architecture of basement membranes

1990 • 937 citations

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 • 805 citations

IκB-β regulates the persistent response in a biphasic activation of NF-κB

1995 • 780 citations

Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.

1993 • 704 citations

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

1992 • 620 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

Diffuse alveolar damage--the role of oxygen, shock, and related factors. A review.

1976 • 516 citations

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB

1995 • 460 citations

Cytokine regulation of metalloproteinase gene expression

1993 • 432 citations

NF-kappa B activation of p53. A potential mechanism for suppressing cell growth in response to stress.

1994 • 361 citations

Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.

1991 • 343 citations

Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes

1991 • 307 citations

The role of intraalveolar fibrosis in the process of pulmonary structural remodeling in patients with diffuse alveolar damage.

1987 • 297 citations

v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.

1993 • 291 citations

Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis.

1988 • 287 citations

Transcriptional Activation by p53 of the Human Type IV Collagenase (Gelatinase A or Matrix Metalloproteinase 2) Promoter

1997 • 278 citations

Monoclonal antibodies specific to apical surfaces of rat alveolar type I cells bind to surfaces of cultured, but not freshly isolated, type II cells

1988 • 256 citations

Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis.

1996 • 234 citations

Extracellular matrix in normal and fibrotic human lungs.

1985 • 200 citations

Matrix metalloproteinases and TIMP in acute respiratory distress syndrome.

1996 • 191 citations

Steps Involved in Activation of the Pro-matrix Metalloproteinase 9 (Progelatinase B)-Tissue Inhibitor of Metalloproteinases-1 Complex by 4-Aminophenylmercuric Acetate and Proteinases

1995 • 189 citations

Higher concentrations of matrix metalloproteinases in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome.

1997 • 186 citations

Developmental Changes of the 26 S Proteasome in Abdominal Intersegmental Muscles of Manduca sexta during Programmed Cell Death

1995 • 152 citations

Fibroblasts isolated after fibrotic lung injury induce apoptosis of alveolar epithelial cells in vitro

1995 • 143 citations

Oxygen pneumonitis in man. Ultrastructural observations on the development of alveolar lesions.

1972 • 116 citations

Exposure to Hyperoxia Induces p53 Expression in Mouse Lung Epithelium

1998 • 110 citations

The rabbit gene for 92-kDa matrix metalloproteinase. Role of AP1 and AP2 in cell type-specific transcription.

1994 • 109 citations

Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes.

1996 • 107 citations

Nuclear Factor-κB Is Activated by Hyperoxia but Does Not Protect from Cell Death

1997 • 106 citations

A 96-kDa gelatinase induced by TNF-alpha contributes to increased microvascular endothelial permeability

1993 • 101 citations

Gelatinases in epithelial lining fluid of patients with adult respiratory distress syndrome

1997 • 101 citations

Evolution of three patterns of intra‐alveolar fibrosis produced by bleomycin in rats

1995 • 94 citations

Tobacco smoke-induced lung emphysema in guinea pigs is associated with increased interstitial collagenase

1996 • 82 citations

Increased expression of gelatinases and collagenase in rat lungs exposed to 100% oxygen.

1996 • 76 citations

Modulation of NF-κB, p53 and Bcl-2 in apoptosis induced by cisplatin in HeLa cells

1997 • 66 citations

Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-kappaB activity

1996 • 62 citations

Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity

1997 • 59 citations

Modulation of M_r 72,000 and M_r 92,000 type‐IV collagenase (gelatinase A and B) gene expression by interferons alpha and gamma in human melanoma

1994 • 58 citations

Increased expression of tissue inhibitor of metalloproteinases (TIMP-I) and metallothionein in murine lungs after hyperoxic exposure.

1994 • 57 citations

Characterization of Rat Uterine Matrilysin and Its cDNA

1995 • 46 citations

TNF alpha gene and protein expression in alveolar macrophages in acute and chronic hyperoxia-induced lung injury.

1996 • 40 citations

Alveolar epithelial cells in vitro produce gelatinases and tissue inhibitor of matrix metalloproteinase-2

1997 • 35 citations

Changes in gene expression in hyperoxia-induced neonatal lung injury

1990 • 34 citations

Lung alveolar epithelial cells synthesize interstitial collagenase and gelatinases A and B in vitro

1997 • 33 citations

Repair of chronic hyperoxic lung injury: Changes in lung ultrastructure and matrix

1987 • 33 citations

Altered expression of type I collagen, TGF-beta 1, and related genes in rat lung exposed to 85% O2

1995 • 15 citations

Purification of a Procollagenase-Acttvator Present in Medium of Cultured Guinea Pig Carrageenin Granuloma

1991 • 12 citations