Factors affecting the transduction of pluripotent hematopoietic stem cells: long-term expression of a human adenosine deaminase gene in mice

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges.

1988 • 908 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Clonal and systemic analysis of long-term hematopoiesis in the mouse.

1990 • 577 citations

Prospects for Human Gene Therapy

1984 • 548 citations

Autoradiography using storage phosphor technology

1990 • 531 citations

Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: evidence for a pre-CFU-S cell?

1979 • 513 citations

Separation of pluripotent haematopoietic stem cells from spleen colony-forming cells

1990 • 414 citations

An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse

1989 • 406 citations

Rapid Cell Culture Assay Technique for Murine Leukaemia Viruses

1971 • 360 citations

Isolation of murine pluripotent hemopoietic stem cells.

1984 • 333 citations

Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.

1985 • 329 citations

Cellular and developmental properties of fetal hematopoietic stem cells

1990 • 317 citations

Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells.

1989 • 316 citations

Gene Expression in Mice After High Efficiency Retroviral-Mediated Gene Transfer

1985 • 281 citations

Life span of multipotential hematopoietic stem cells in vivo.

1990 • 228 citations

Immunodeficiency diseases caused by adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency.

1995 • 217 citations

Studies of hematopoietic stem cells spared by 5-fluorouracil.

1984 • 213 citations

Separation of CFU-S from primitive cells responsible for reconstitution of the bone marrow hemopoietic stem cell compartment following irradiation: evidence for a pre-CFU-S cell.

1989 • 209 citations

A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3.

1985 • 174 citations

Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells.

1987 • 168 citations

Evidence for structured variation in self-renewal capacity within long-term bone marrow cultures.

1980 • 153 citations

Stromal support enhances cell-free retroviral vector transduction of human bone marrow long-term culture-initiating cells

1992 • 141 citations

Survival and retrovirus infection of murine hematopoietic stem cells in vitro: effects of 5-FU and method of infection.

1991 • 137 citations

Expression of human adenosine deaminase in murine hematopoietic cells.

1988 • 112 citations

Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes

1988 • 111 citations

Metabolically inactive 3T3 cells can substitute for marrow stromal cells to promote the proliferation and development of multipotent haemopoietic stem cells

1987 • 110 citations

Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo

1988 • 102 citations

Cells with marrow and spleen repopulating ability and forming spleen colonies on day 16, 12, and 8 are sequentially ordered on the basis of increasing rhodamine 123 retention

1988 • 101 citations

Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses.

1987 • 97 citations

Stromal support enhances cell-free retroviral vector transduction of human bone marrow long-term culture-initiating cells

1992 • 93 citations

Expression of Introduced Genetic Sequences in Hematopoietic Cells Following Retroviral-Mediated Gene Transfer

1990 • 92 citations

Modulation of gene expression in multiple hematopoietic cell lineages following retroviral vector gene transfer.

1987 • 89 citations

Retrovirus-mediated gene transfer of human adenosine deaminase: expression of functional enzyme in murine hematopoietic stem cells in vivo.

1987 • 89 citations

Suppression of leukaemia virus pathogenicity by polyoma virus enhancers

1985 • 87 citations

Net increase of pluripotential hematopoietic precursors in suspension culture in response to IL-1 and IL-3.

1989 • 83 citations

Expression of human adenosine deaminase in mice transplanted with hemopoietic stem cells infected with amphotropic retroviruses.

1990 • 67 citations

Marrow repopulating cells, but not CFU-S, establish long-term in vitro hemopoiesis on a marrow-derived stromal layer.

1990 • 58 citations

Human adenosine deaminase expression in mice

1990 • 53 citations

Murine leukemia inhibitory factor enhances retroviral-vector infection efficiency of hematopoietic progenitors

1990 • 50 citations

Retrovirus-mediated gene transfer into embryonal carcinoma and hemopoietic stem cells: expression from a hybrid long terminal repeat

1989 • 38 citations

Human Purine Nucleoside Phosphorylase and Adenosine Deaminase: Gene Transfer into Cultured Cells and Murine Hematopoietic Stem Cells by Using Recombinant Amphotropic Retroviruses

1987 • 31 citations

An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse

1989 • 29 citations

Expression of Human Adenosine Deaminase in Murine Hematopoietic Cells

1988 • 27 citations

In vivo proliferative and differential properties of murine bone marrow cells separated on the basis of rhodamine-123 retention.

1988 • 27 citations

Retrovirus-Mediated Gene Transfer of Human Adenosine Deaminase: Expression of Functional Enzyme in Murine Hematopoietic Stem Cells In Vivo

1987 • 26 citations

IL-6 Production by Retrovirus Packaging Cells and Cultured Bone Marrow Cells

1991 • 13 citations

Human adenosine deaminase expression in mice

1990 • 7 citations

Murine leukemia inhibitory factor enhances retroviral-vector infection efficiency of hematopoietic progenitors

1990 • 7 citations