Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2).

Clinical Applications of Research on Angiogenesis

1995 • 2,300 citations

Molecular classification of cutaneous malignant melanoma by gene expression profiling

2000 • 2,011 citations

Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry

1999 • 1,921 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?

1997 • 959 citations

Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?

1997 • 920 citations

Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

1995 • 760 citations

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

1999 • 542 citations

Role of B61, the Ligand for the Eck Receptor Tyrosine Kinase, in TNF-α-Induced Angiogenesis

1995 • 368 citations

E-cadherin regulates the function of the EphA2 receptor tyrosine kinase.

1999 • 248 citations

Trophoblast pseudo-vasculogenesis: faking it with endothelial adhesion receptors

1998 • 246 citations

B61 is a ligand for the ECK receptor protein-tyrosine kinase

1994 • 239 citations

cDNA Cloning and Characterization of eck, an Epithelial Cell Receptor Protein-Tyrosine Kinase in the eph/elk Family of Protein Kinases

1990 • 234 citations

Extent of vascularization as a prognostic indicator in thin (< 0.76 mm) malignant melanomas.

1994 • 230 citations

Phosphoinositide 3-Kinase Induces Scattering and Tubulogenesis in Epithelial Cells through a Novel Pathway

1998 • 216 citations

The Eph family of receptors

1997 • 205 citations

Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity.

1994 • 151 citations

Up-regulation of ephrin-a1 during melanoma progression

1999 • 127 citations

Characterization of a Novel Src-like Adapter Protein That Associates with the Eck Receptor Tyrosine Kinase

1995 • 127 citations

Molecular role(s) for integrins in human melanoma invasion.

1999 • 119 citations

Epithelial cell kinase-B61: an autocrine loop modulating intestinal epithelial migration and barrier function

1997 • 107 citations

Protein B61 as a new growth factor: expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression.

1995 • 107 citations

Abnormal protein tyrosine kinase gene expression during melanoma progression and metastasis

1995 • 104 citations

Drosophila in cancer research

2000 • 103 citations

Tumor Plasticity Allows Vasculogenic Mimicry, a Novel Form of Angiogenic Switch

1999 • 96 citations

cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

1995 • 69 citations

Novel and Known Protein Tyrosine Kinases and Their Abnormal Expression in Human Melanoma

1993 • 39 citations

Vascular density does not predict future metastatic disease in clinical stage 1 non‐seminomatous germ cell tumours of the testis

1998 • 10 citations