Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Une micro-méthode de l’immuno-électrophorèse

1955 • 3,859 citations

A simple and rapid method for the permethylation of carbohydrates

1984 • 3,459 citations

Glycoprotein staining following electrophoresis on acrylamide gels

1969 • 1,947 citations

Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids

1961 • 1,909 citations

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

1991 • 564 citations

Defective acidification of intracellular organelles in cystic fibrosis

1991 • 490 citations

Regulation of Plasma Membrane Recycling by CFTR

1992 • 339 citations

CD62/P-selectin recognition of myeloid and tumor cell sulfatides

1991 • 304 citations

Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein

1992 • 237 citations

Increased sulfation of glycoconjugates by cultured nasal epithelial cells from patients with cystic fibrosis.

1989 • 216 citations

Erythrocyte receptors for Mycoplasma pneumoniae are sialylated oligosaccharides of Ii antigen type

1984 • 192 citations

Gas-liquid chromatography and mass spectrometry of methylated and acetylated methyl glycosides. Application to the structural analysis of glycoprotein glycans

1981 • 191 citations

High affinity binding of the leucocyte adhesion molecule L-selectin to 3′-sulphated-Lea and -Lex oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides

1992 • 173 citations

The ultramicro determination of inorganic sulphate

1960 • 151 citations

Adhesion of Mycoplasma pneumoniae to Sulfated Glycolipids and Inhibition by Dextran Sulfate

1989 • 149 citations

Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin.

1994 • 145 citations

Heterogeneity of the carbohydrate chains of sulfated bronchial glycoproteins isolated from a patient suffering from cystic fibrosis.

1975 • 144 citations

Primary-Structure Determination of Fourteen Neutral Oligosaccharides Derived from Bronchial-Mucus Glycoproteins of Patients Suffering from Cystic Fibrosis, Employing 500-MHz 1H-NMR Spectroscopy

1982 • 132 citations

Sialic Acid-Dependent Adhesion of Mycoplasma pneumoniae to Purified Glycoproteins

1989 • 130 citations

Isolation and structural characterization of low‐molecular‐mass monosialyl oligosaccharides derived from respiratory‐mucus glycoproteins of a patient suffering from bronchiectasis

1988 • 121 citations

The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH.

1992 • 120 citations

The Carbohydrate Diversity of Human Respiratory Mucins: A Protection of the Underlying Mucosa?

1991 • 120 citations

Structure determination by 1H NMR spectroscopy of (sulfated) sialylated N-linked carbohydrate chains released from porcine thyroglobulin by peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase-F

1991 • 112 citations

Primary structure determination of five sialylated oligosaccharides derived from bronchial mucus glycoproteins of patients suffering from cystic fibrosis. The occurrence of the NeuAc alpha(2----3)Gal beta(1----4)[Fuc alpha(1----3)] GlcNAc beta(1----.) structural element revealed by 500-MHz 1H NMR spectroscopy.

1984 • 106 citations

Structural studies on the bacterial lyase-resistant tetrasaccharides derived from the antithrombin III-binding site of porcine intestinal heparin.

1993 • 91 citations

A 360-MHz 1H-NMR study of three oligosaccharides isolated from cow κ-casein

1980 • 90 citations

Complex structure of human bronchial mucus glycoprotein

1984 • 90 citations

Primary structure of neutral oligosaccharides derived from respiratory‐mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500‐MHz ¹H‐NMR spectroscopy and quantitative sugar analysis

1988 • 88 citations

Structural studies on the O-linked carbohydrate chains of human platelet glycocalicin

1984 • 85 citations

Structures of O‐glycosidically linked oligosaccharides isolated from human meconium glycoproteins

1989 • 83 citations

Altered Carbohydrate Composition of Salivary Mucins from Patients with Cystic Fibrosis and the Adhesion of Pseudomonas aeruginosa

1993 • 80 citations

Structure of sialyl-oligosaccharides isolated from bronchial mucus glycoproteins of patients (blood group O) suffering from cystic fibrosis

1987 • 77 citations

Structure determination of five sulfated oligosaccharides derived from tracheobronchial mucus glycoproteins.

1987 • 72 citations

Abnormal Respiratory Epithelial Ion Transport in Cystic Fibrosis

1986 • 67 citations

Sulfated sialyl-oligosaccharides derived from tracheobronchial mucous glycoproteins of a patient suffering from cystic fibrosis.

1992 • 60 citations

1H- and 13C-n.m.r. spectroscopy of synthetic monosulphated methyl α-d-galactopyranosides

1988 • 57 citations

Primary structure of neutral oligosaccharides derived from respiratory‐mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500‐MHz ¹H‐NMR spectroscopy and quantitative sugar analysis

1988 • 54 citations

Highly simplified analytical or preparative slab gel electrophoresis

1978 • 51 citations

Chondroitin Sulfate in Sputum from Patients with Cystic Fibrosis and Chronic Bronchitis

1991 • 49 citations

The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins

1992 • 49 citations

Structure of two sulphated oligosaccharides from respiratory mucins of a patient suffering from cystic fibrosis. A fast-atom-bombardment m.s. and 1H-n.m.r. spectroscopic study

1991 • 47 citations

Hemophilus Influenzae, Staphylococcus aureus, Pseudomonas cepacia, and Pseudomonas aeruginosa in Patients with Cystic Fibrosis

1988 • 44 citations

Determination of the structure of sulfated tetra- and pentasaccharides obtained by alkaline borohydride degradation of hen ovomucin. A fast atom bombardment-mass spectrometric and1H-NMR spectroscopic study

1987 • 39 citations

Structural analysis of monosulfated side-chain oligosaccharides isolated from human tracheobronchial mucous glycoproteins

1992 • 37 citations

Defective epithelial ion transport in cystic fibrosis.

1989 • 37 citations

Inhibition of infection with human immunodeficiency virus type 1 by sulfated gangliosides

1991 • 36 citations

Complete 1H- and 13C-n.m.r. assignments for two sulphated oligosaccharide alditols of hen ovomucin

1989 • 34 citations

Structural analysis of the carbohydrate chains of mucin-type glycoproteins by high-resolution 1H-n.m.r. spectroscopy

1984 • 31 citations

Blocking of the receptor‐mediated invasion of erythrocytes by Plasmodium knowlesi malaria with sulfated polysaccharides and glycosaminoglycans

1991 • 29 citations

The carbohydrate chains of the β subunit of human chorionic gonadotropin produced by the choriocarcinoma cell line BeWo

1992 • 29 citations

Action of trifluoromethanesulfonic acid on highly glycosylated regions of human bronchial mucins

1986 • 28 citations

Les glycopeptides du mucus bronchique fibrillaire dans la mucoviscidose

1972 • 21 citations

Micro-electrophoresis of mucopolysaccharides on agarose gel

1963 • 13 citations