The effect of GDP on rod outer segment G-protein interactions.

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes

1980 • 561 citations

Characterization of transducin from bovine retinal rod outer segments. I. Separation and reconstitution of the subunits.

1983 • 492 citations

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.

1980 • 391 citations

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

1978 • 372 citations

Light-activated phosphodiesterase of the rod outer segment. Kinetics and parameters of activation and deactivation.

1978 • 353 citations

High performance liquid chromatography: a rapid isocratic method for determination of creatine compounds and adenine nucleotides in myocardial tissue

1986 • 294 citations

Light-dependent phosphorylation of rhodopsin. Purification and properties of rhodopsin kinase.

1978 • 291 citations

Characterization of bovine rod outer segment G-protein.

1982 • 281 citations

The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.

1986 • 261 citations

Complex formation between metarhodopsin II and GTP‐binding protein in bovine protoreceptor membranes leads to a shift of the photoproduct equilibrium

1982 • 259 citations

Interactions between photoexcited rhodopsin and GTP-binding protein: kinetic and stoichiometric analyses from light-scattering changes.

1981 • 247 citations

Membrane-dependent guanine nucleotide binding and GTPase activities of soluble protein from bovine rod cell outer segments.

1979 • 183 citations

Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its γ subunit and transducin

1986 • 151 citations

Resolution, reconstitution and kinetics of the primary action of a hormone receptor

1980 • 149 citations

[72] Real time assay of rod disk membrane cGMP phosphodiesterase and its controller enzymes

1982 • 125 citations

The G-protein of retinal rod outer segments (transducin). Mechanism of interaction with rhodopsin and nucleotides.

1985 • 122 citations

Temperature and pH dependence of the metarhodopsin I-metarhodopsin II kinetics and equilibria in bovine rod disk membrane suspensions

1984 • 117 citations

The Molecules of Visual Excitation

1987 • 109 citations

Gain, speed and sensitivity of GTP binding vs PDE activation in visual excitation

1982 • 86 citations

Regulation of hormone-receptor coupling to adenylyl cyclase. Effects of GTP and GDP.

1980 • 85 citations

GDP does not mediate but rather inhibits hormonal signal to adenylate cyclase.

1983 • 77 citations

Shift in the relation between flash‐induced metarhodopsin I and metarhodopsin II within the first 10% rhodopsin bleaching in bovine disc membranes

1981 • 70 citations

Mechanism of action of monoclonal antibodies that block the light activation of the guanyl nucleotide-binding protein, transducin.

1987 • 69 citations

Light-induced, reversible binding of proteins to bovine photoreceptor membranes. Influence of nucleotides

1980 • 47 citations

Rod outer segment phosphodiesterase binding and activation in reconstituted membranes

1984 • 37 citations

Temperature dependence of G-protein activation in photoreceptor membranes. Transient extra metarhodopsin II on bovine disk membranes

1987 • 35 citations

Sensitive light scattering probe of enzymatic processes in retinal rod photoreceptor membranes

1984 • 32 citations

Mechanism of cGMP control in retinal rod outer segments

1984 • 20 citations