Identification and cloning of the SNARE proteins VAMP-2 and syntaxin-4 from HL-60 cells and human neutrophils.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

SNAREpins: Minimal Machinery for Membrane Fusion

1998 • 2,456 citations

The molecular machinery for secretion is conserved from yeast to neurons.

1993 • 658 citations

Synaptic vesicle biogenesis, docking, and fusion: a molecular description

1996 • 349 citations

Two Vesicle-associated Membrane Protein Genes Are Differentially Expressed in the Rat Central Nervous System

1989 • 326 citations

Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase.

1989 • 310 citations

Movement of proteins through the Golgi stack: a molecular dissection of vesicular transport ¹

1990 • 151 citations

Cytoplasmic phospholipase A2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase.

1994 • 149 citations

Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments.

1995 • 144 citations

Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.

1990 • 144 citations

Separation of mononuclear and polymorphonuclear leucocytes from human blood by the one-step hypaque-ficoll method is dependent on blood column height

1982 • 143 citations

Fusion of newly formed phagosomes with endosomes in intact cells and in a cell-free system.

1991 • 141 citations

Regulatory Role for GTP-Binding Proteins in Endocytosis

1989 • 138 citations

The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils

1994 • 124 citations

Exocytosis: Proteins and Perturbations

1996 • 123 citations

The receptors for ATP and fMetLeuPhe are independently coupled to phospholipases C and A2 via G-protein(s). Relationship between phospholipase C and A2 activation and exocytosis in HL60 cells and human neutrophils

1989 • 123 citations

Human neutrophil annexin I promotes granule aggregation and modulates Ca(2+)-dependent membrane fusion.

1992 • 82 citations

Tyrosine kinase and phosphotyrosine phosphatase activity in human promyelocytic leukemia cells and human polymorphonuclear leukocytes

1987 • 69 citations

High resolution of heterogeneity among human neutrophil granules: physical, biochemical, and ultrastructural properties of isolated fractions

1986 • 66 citations

Secrets of Secretion Revealed

1993 • 65 citations

Phospholipase D activity facilitates Ca2+-induced aggregation and fusion of complex liposomes

1997 • 62 citations

Identification of glyceraldehyde-3-phosphate dehydrogenase as a Ca2+-dependent fusogen in human neutrophil cytosol

1998 • 54 citations

Identification of Two Isoforms of the Vesicle-Membrane Fusion Protein SNAP-23 in Human Neutrophils and HL-60 Cells

1997 • 52 citations

SNAREs and targeted membrane fusion

1995 • 51 citations

Characterization of the mechanism of endocytic vesicle fusion in vitro.

1990 • 51 citations

Neutrophil activation and function in health and disease.

1992 • 47 citations

Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1

1999 • 47 citations

Phospholipase A2 activity in human neutrophils. Stimulation by lipopolysaccharide and possible involvement in priming for an enhanced respiratory burst.

1993 • 47 citations

Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2

1996 • 46 citations

Epstein-Barr virus modulates de novo protein synthesis in human neutrophils

1995 • 38 citations

Intracellular Location of SNAP-25 in Human Neutrophils

1997 • 37 citations

Botulinum and Tetanus Neurotoxins: Emerging Tools for the Study of Membrane Fusion

1995 • 32 citations

Incorporation of [32P]orthophosphate into inorganic polyphosphates by human granulocytes and other human cell types

1994 • 31 citations

PLA2 promotes fusion between PMN-specific granules and complex liposomes

1996 • 31 citations

Activation of cytosolic phospholipase A2 in permeabilized human neutrophils

1996 • 25 citations

Spin traps inhibit formation of hydrogen peroxide via the dismutation of superoxide: implications for spin trapping the hydroxyl free radical

1991 • 20 citations

Membrane fusion: All done with SNAREpins?

1998 • 20 citations

Calcium-dependent fusion of the plasma membrane fraction from human neutrophils with liposomes

1990 • 17 citations

Development of an aqueous-space mixing assay for fusion of granules and plasma membranes from human neutrophils

1996 • 10 citations

Induction of Proteins in Interferon-α- and Interferon-γ-Treated Polymorphonuclear Leukocytes

1989 • 9 citations

Proteins Involved in Synaptic Vesicle Docking and Fusion

1995 • 4 citations