Preclinical MRI experience in imaging angiogenesis.

Estimating kinetic parameters from dynamic contrast-enhanced t1-weighted MRI of a diffusable tracer: Standardized quantities and symbols

1999 • 3,063 citations

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1998 • 2,427 citations

Oxygenation‐sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields

1990 • 2,225 citations

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1999 • 1,248 citations

Blood Vessel Formation: What Is Its Molecular Basis?

1996 • 1,242 citations

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.

2000 • 1,087 citations

Detection of tumor angiogenesis in vivo by αvβ3-targeted magnetic resonance imaging

1998 • 851 citations

Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.

1995 • 598 citations

Three-dimensional cell cultures: from molecular mechanisms to clinical applications

1997 • 527 citations

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1997 • 512 citations

NMR imaging of changes in vascular morphology due to tumor angiogenesis

1998 • 342 citations

Tissue specific perfusion imaging using arterial spin labeling

1994 • 328 citations

Assessing tumor angiogenesis using macromolecular MR imaging contrast media

1997 • 256 citations

New perspectives in clinical oncology from angiogenesis research

1996 • 253 citations

MR imaging of tumor microcirculation: Promise for the new millenium

1999 • 227 citations

Multicellular tumor spheroids: intermediates between monolayer culture and in vivo tumor

1999 • 214 citations

Magnetic Resonance Imaging Detects Suppression of Tumor Vascular Permeability After Administration of Antibody to Vascular Endothelial Growth Factor

1998 • 206 citations

Stimulation of tumour growth by wound-derived growth factors

1999 • 187 citations

Angiogenesis of uterine cervical carcinoma: characterization by pharmacokinetic magnetic resonance parameters and histological microvessel density with correlation to lymphatic involvement.

1997 • 148 citations

The response of human tumors to carbogen breathing, monitored by gradient-recalled echo magnetic resonance imaging

1997 • 130 citations

In vivo prediction of vascular susceptibility to vascular susceptibility endothelial growth factor withdrawal: magnetic resonance imaging of C6 rat glioma in nude mice.

1999 • 114 citations

Loss of ovarian function promotes angiogenesis in human ovarian carcinoma

1997 • 110 citations

Magnetic resonance imaging and spectroscopy of combretastatin A4 prodrug-induced disruption of tumour perfusion and energetic status

1998 • 101 citations

Abnormalities of the contrast re-circulation phase in cerebral tumors demonstrated using dynamic susceptibility contrast-enhanced imaging: A possible marker of vascular tortuosity

2000 • 90 citations

Intercellular communication between vascular smooth muscle and endothelial cells mediated by heparin‐binding epidermal growth factor‐like growth factor and vascular endothelial growth factor

1998 • 89 citations

Dynamic contrast-enhanced magnetic resonance imaging reveals stress-induced angiogenesis in MCF7 human breast tumors.

1996 • 84 citations

Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging

1998 • 83 citations

Inhibition of Neovascularization and Tumor Growth, Facilitation of Wound Repair, by Halofuginone, an Inhibitor of Collagen Type I Synthesis

1999 • 70 citations

Neovascularization induced growth of implanted C6 glioma multicellular spheroids: magnetic resonance microimaging.

1995 • 69 citations

Dynamic Remodeling of the Vascular Bed Precedes Tumor Growth: MLS Ovarian Carcinoma Spheroids Implanted in Nude Mice

1999 • 60 citations

Tumor Angiogenesis, Vascularization, and Contrast-Enhanced Magnetic Resonance Imaging

1999 • 59 citations

Stimulation of tumour angiogenesis by proximal wounds: spatial and temporal analysis by MRI

1998 • 56 citations

Treatment of Experimental Brain Tumors with Trombospondin-1 Derived Peptides: an In Vivo Imaging Study

1999 • 43 citations

The antiangiogenic agent linomide inhibits the growth rate of von Hippel-Lindau paraganglioma xenografts to mice.

1999 • 30 citations

Response of MCF7 human breast cancer to tamoxifen: evaluation by the three-time-point, contrast-enhanced magnetic resonance imaging method.

1998 • 28 citations

Tumor angiogenesis: A physiological process or genetically determined?

1996 • 27 citations

Angiogenic response of MCF7 human breast cancer to hormonal treatment: Assessment by dynamic GdDTPA‐enhanced MRI at high spatial resolution

1996 • 23 citations

Perfusion of the rat ovary: Application of pulsed arterial spin labeling MRI

1999 • 18 citations

Spatial and temporal modulation of perfusion in the rat ovary measured by arterial spin labeling MRI

1999 • 17 citations

The Behaviour of the Tissue pO2 in Transparent Chambers of Rats with and Without Tumour Implantations

1985 • 1 citations