Differences between agonist and antagonist binding following beta-adrenergic receptor desensitization.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites.

1975 • 381 citations

An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.

1976 • 318 citations

Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides.

1976 • 314 citations

Rapid changes in rat pineal beta-adrenergic receptor: alterations in l-(3H)alprenolol binding and adenylate cyclase.

1975 • 265 citations

Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro.

1975 • 235 citations

Slowly reversible binding of catecholamine to a nucleotide-sensitive state of the beta-adrenergic receptor.

1977 • 228 citations

Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells.

1976 • 219 citations

Gonadotropin-induced loss of hormone receptors and desensitization of adenylate cyclase in the ovary.

1976 • 208 citations

Regulation of prostaglandin receptors by prostaglandins and guanine nucleotides in frog erythrocytes.

1977 • 177 citations

Stimulation and Desensitization of Macrophage Adenylate Cyclase by Prostaglandins and Catecholamines

1974 • 166 citations

Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding.

1976 • 164 citations

Catecholamine binding to the beta-adrenergic receptor.

1977 • 134 citations

Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells.

1978 • 130 citations

Regulation of Adenylate Cyclase Coupled β-Adrenergic Receptors by β-Adrenergic Catecholamines

1976 • 123 citations

Regulation of adenylate cyclase-coupled beta adrenergic receptor binding sites by beta adrenergic catecholamines in vitro.

1976 • 119 citations

Reversal of Catecholamine Refractoriness by Inhibitors of RNA and Protein Synthesis

1974 • 111 citations

Binding of (3H)prostaglandin E1 to putative receptors linked to adenylate cyclase of cultured cell clones.

1976 • 109 citations

Adenylate cyclase-coupled beta adrenergic receptors effect of membrane lipid-perturbing agents on receptor binding and enzyme stimulation by catecholamines.

1976 • 101 citations

Structure-activity relationships of adenylate cyclase-coupled beta adrenergic receptors: determination by direct binding studies.

1976 • 100 citations

Human synoviocytes: activation and desensitization by prostaglandins and 1-epinephrine.

1975 • 79 citations

Conformational Changes in Ribosomes during Protein Synthesis

1971 • 68 citations

Desensitization of Beta Adrenergic Receptors in Human Fibroblasts in Tissue Culture

1975 • 46 citations

Comparison of specificity of agonist and antagonist radioligand binding to β adrenergic receptors

1977 • 19 citations