Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

1970 • 3,269 citations

Cyclic AMP

1968 • 954 citations

Mouse myelomas and lymphomas in culture

1970 • 559 citations

The influence of chemical agents on the accumulation of adenosine 3',5'-Phosphate in slices of rabbit cerebellum.

1968 • 435 citations

Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites.

1975 • 381 citations

Selection of a Variant Lymphoma Cell Deficient in Adenylate Cyclase

1975 • 276 citations

Rapid changes in rat pineal beta-adrenergic receptor: alterations in l-(3H)alprenolol binding and adenylate cyclase.

1975 • 265 citations

Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.

1976 • 238 citations

Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro.

1975 • 235 citations

Effects of Lipolytic and Antilipolytic Agents on Cyclic 3',5'-Adenosine Monophosphate in Fat Cells

1971 • 199 citations

Resistance to -adrenoceptor stimulants (a possible explanation for the rise in ashtma deaths).

1971 • 190 citations

Formation and Release of a Hormone Antagonist by Rat Adipocytes

1971 • 175 citations

Stimulation and Desensitization of Macrophage Adenylate Cyclase by Prostaglandins and Catecholamines

1974 • 166 citations

Cyclic AMP-Dependent Protein Kinase: Pivotal Role in Regulation of Enzyme Induction and Growth

1975 • 164 citations

Induction and Superinduction of Serotonin N -Acetyltransferase by Adrenergic Drugs and Denervation in Rat Pineal Organ

1972 • 160 citations

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Phosphodiesterase Activity in Fibroblasts by Intracellular Concentrations of Cyclic Adenosine Monophosphate

1972 • 141 citations

Somatic genetic analysis of cyclic AMP action: Selection of unresponsive mutants

1975 • 132 citations

Regulation of adenylate cyclase-coupled beta adrenergic receptor binding sites by beta adrenergic catecholamines in vitro.

1976 • 119 citations

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

1976 • 116 citations

Properties of Adenylate Cyclase of Lymphoid Cells

1971 • 114 citations

Reversal of Catecholamine Refractoriness by Inhibitors of RNA and Protein Synthesis

1974 • 111 citations

Resistance to β‐adrenoceptor stimulants (a possible explanation for the rise in asthma deaths)

1971 • 106 citations

Somatic genetic analysis of cyclic AMP action: Characterization of unresponsive mutants

1975 • 96 citations

Regulation of Phosphodiesterase Synthesis: Requirement for Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1973 • 93 citations

The Effects of Epinephrine and Prostaglandin E1 on Cyclic Adenosine 3′ : 5′-Monophosphate Levels in WI-38 Fibroblasts

1974 • 90 citations

Human synoviocytes: activation and desensitization by prostaglandins and 1-epinephrine.

1975 • 79 citations

Regulation of adenosine 3' :5'-monophosphate efflux from rat glioma cells in culture*

1975 • 69 citations

Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells

1975 • 56 citations

Desensitization of Beta Adrenergic Receptors in Human Fibroblasts in Tissue Culture

1975 • 46 citations

Mechanism for the Chromosome Banding Phenomenon

1973 • 41 citations

Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding

1974 • 38 citations

Reduction in isoprenaline-induced cyclic AMP formation in guinea-pig heart after exposure to isoprenaline or salbutamol

1975 • 8 citations