Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: A mechanism for cellular human immunodeficiency virus 1 infection

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

B lymphocytes secrete antigen-presenting vesicles.

1996 • 3,198 citations

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1996 • 2,883 citations

CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and Disease

1999 • 2,174 citations

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell derived exosomes

1998 • 2,078 citations

Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells

1997 • 1,321 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

Elevated Levels of Shed Membrane Microparticles With Procoagulant Potential in the Peripheral Circulating Blood of Patients With Acute Coronary Syndromes

2000 • 876 citations

In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant

1999 • 720 citations

Shed Membrane Microparticles With Procoagulant Potential in Human Atherosclerotic Plaques

1999 • 619 citations

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

1998 • 568 citations

Modulation of monocyte-endothelial cell interactions by platelet microparticles.

1998 • 531 citations

Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles.

1997 • 486 citations

Cellular reservoirs of HIV-1 in the central nervous system of infected individuals

1996 • 412 citations

Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

1998 • 409 citations

Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharide.

1994 • 367 citations

Endothelial Cell Activation by Leukocyte Microparticles

1998 • 365 citations

Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis

1999 • 317 citations

Cellular and Anatomical Reservoirs of HIV-1 in Patients Receiving Potent Antiretroviral Combination Therapy

1998 • 310 citations

In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system.

1994 • 283 citations

Isolation of human platelet membrane microparticles from plasma and serum

1982 • 281 citations

Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.

1997 • 267 citations

CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

1997 • 264 citations

Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome

1994 • 230 citations

HIV-1 Coreceptor Activity of CCR5 and Its Inhibition by Chemokines: Independence from G Protein Signaling and Importance of Coreceptor Downmodulation

1997 • 214 citations

Expression of Chemokine Receptors CXCR4 and CCR5 in HIV-1-Infected and Uninfected Individuals

1998 • 213 citations

Cytosolic Gag p24 as an Index of Productive Entry of Human Immunodeficiency Virus Type 1

1998 • 206 citations

Chemokine Receptor Expression and Signaling in Macaque and Human Fetal Neurons and Astrocytes: Implications for the Neuropathogenesis of AIDS

1999 • 202 citations

Differential Effects of CC Chemokines on CC Chemokine Receptor 5 (CCR5) Phosphorylation and Identification of Phosphorylation Sites on the CCR5 Carboxyl Terminus

1999 • 186 citations

HIV-1 Entry and Macrophage Inflammatory Protein-1β-mediated Signaling Are Independent Functions of the Chemokine Receptor CCR5

1997 • 183 citations

Constitutive cell surface association between CD4 and CCR5

1999 • 179 citations

Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

1997 • 176 citations

Expression of the C-C chemokine receptor 5 in human kidney diseases

1999 • 173 citations

Cell Membrane Vesicles Are a Major Contaminant of Gradient-Enriched Human Immunodeficiency Virus Type-1 Preparations

1997 • 149 citations

Shedding of vesicular material from the cell surface of eukaryotic cells: different cellular phenomena

1991 • 136 citations

CCR5-Reactive Antibodies in Seronegative Partners of HIV-Seropositive Individuals Down-Modulate Surface CCR5 In Vivo and Neutralize the Infectivity of R5 Strains of HIV-1 In Vitro

2000 • 120 citations

Nonproductive Human Immunodeficiency Virus Type 1 Infection of Human Fetal Astrocytes: Independence from CD4 and Major Chemokine Receptors

1999 • 110 citations

Infection of human primary renal epithelial cells with HIV-1 from children with HIV-associated nephropathy

1998 • 109 citations

CC Chemokine Receptor 5 Cell-Surface Expression in Relation to CC Chemokine Receptor 5 Genotype and the Clinical Course of HIV-1 Infection

1999 • 99 citations

A trans-receptor mechanism for infection of CD4-negative cells by human immunodeficiency virus type 1

1999 • 50 citations

Structurally distinct plasma membrane regions give rise to extracellular membrane vesicles in normal and transformed lymphocytes

1988 • 38 citations

The monoclonal CD4 antibody M-T413 inhibits cellular infection with human immunodeficiency virus after viral attachment to the cell membrane: an approach to postexposure prophylaxis.

1992 • 29 citations

Platelet glycoproteins IIb and IIIa associated with blood monocytes are derived from platelets

1986 • 26 citations

Production of HIV-1 by Human B Cells Infectedin Vitro:Characterization of an EBV Genome-Negative B Cell Line Chronically Synthetizing a Low Level of HIV-1 after Infection

1998 • 21 citations