Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

1992 • 1,342 citations

rab5 controls early endosome fusion in vitro

1991 • 1,090 citations

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

1994 • 948 citations

Rab9 functions in transport between late endosomes and the trans Golgi network.

1993 • 556 citations

Small GTP-Binding Proteins

1992 • 526 citations

Hypervariable C-termmal domain of rab proteins acts as a targeting signal

1991 • 394 citations

Rab GTPases in vesicular transport

1993 • 379 citations

Friends and family: The role of the rab GTPases in vesicular traffic

1993 • 364 citations

Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan.

1988 • 335 citations

Retinal Degeneration in Choroideremia: Deficiency of Rab Geranylgeranyl Transferase

1993 • 325 citations

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys.

1992 • 323 citations

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

1993 • 322 citations

Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins.

1993 • 318 citations

Cloning of a gene that is rearranged in patients with choroideraemia

1990 • 318 citations

Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic.

1989 • 314 citations

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

1994 • 313 citations

Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein.

1990 • 305 citations

Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product

1992 • 296 citations

GTP-binding proteins in intracellular transport

1992 • 277 citations

Rab proteins and the road maps for intracellular transport

1993 • 276 citations

Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.

1990 • 268 citations

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

1994 • 230 citations

A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments.

1994 • 226 citations

Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4

1993 • 190 citations

REP-2, a Rab escort protein encoded by the choroideremia-like gene.

1994 • 183 citations

The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins.

1992 • 174 citations

Distinct structural elements of rab5 define its functional specificity.

1994 • 163 citations

Rab GDI: a solubilizing and recycling factor for rab9 protein.

1993 • 152 citations

Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver.

1990 • 119 citations

Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cells.

1994 • 118 citations

A novel role for RhoGDI as an inhibitor of GAP proteins.

1993 • 117 citations

cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase

1993 • 94 citations

Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein.

1991 • 87 citations

Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types.

1994 • 79 citations

The role of lipid anchors for small G proteins in membrane trafficking

1992 • 78 citations

Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.

1994 • 76 citations

An autosomal homologue of the choroideremia gene colocalizes with the usher syndrome type II locus on the distal part of chromosome 1q

1992 • 70 citations

Determination of structural requirements for the interaction of Rab6 with RabGDI and Rab geranylgeranyltransferase.

1994 • 65 citations

Isoprenylation of rab proteins on structurally distinct cysteine motifs

1992 • 56 citations

Phosphorylation of GDI and membrane cycling of rab proteins

1993 • 51 citations

Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks.

1994 • 51 citations

The N-terminal domain of a rab protein is involved in membrane-membrane recognition and/or fusion.

1994 • 41 citations

Cloning, Characterization, and Expression of a Novel GDP Dissociation Inhibitor Isoform from Skeletal Muscle

1994 • 23 citations

Small GTP-binding proteins as compartmental markers

1992 • 17 citations

Role of the C-Terminal Region of smg p25A in Its Interaction with Membranes and the GDP/GTP Exchange Protein

1991 • 16 citations

Two fingers for membrane traffic

1993 • 4 citations