Molecular structure of crystalline Streptomyces griseus protease A at 2.8 Å resolution

Solvent content of protein crystals

1968 • 7,954 citations

A semi-empirical method of absorption correction

1968 • 7,409 citations

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units

1968 • 1,497 citations

Serine Proteases: Structure and Mechanism of Catalysis

1977 • 1,238 citations

Stereochemical Criteria for Polypeptide and Protein Chain Conformations

1965 • 715 citations

Structure of crystalline α-chymotrypsin

1972 • 675 citations

Real-space refinement of the structure of hen egg-white lysozyme

1974 • 516 citations

The Three-Dimensional Structure of Ribonuclease-S

1970 • 510 citations

The treatment of errors in the isomorphous replacement method

1959 • 497 citations

The refined crystal structure of bovine β-trypsin at 1·8 Å resolution

1975 • 462 citations

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

1973 • 449 citations

Structure and mechanism of chymotrypsin

1976 • 449 citations

Tests for comparing related amino-acid sequences. Cytochrome c and cytochrome c551

1971 • 440 citations

Subtilisin. Stereochemical mechanism involving transition-state stabilization

1972 • 376 citations

Structure of crystalline α-chymotrypsin

1969 • 374 citations

Structure of crystalline α-chymotrypsin

1970 • 344 citations

The matching of physical models to three-dimensional electron-density maps: A simple optical device

1968 • 313 citations

Three-dimensional Structure of Tosyl-elastase

1970 • 299 citations

The accuracy of electron-density maps in X-ray analysis with special reference to dibenzyl

1949 • 243 citations

Crystal structure of bovine trypsinogen at 1·8 Å resolution

1977 • 242 citations

Carbon nuclear magnetic resonance studies of the histidine residue in α-lytic protease. Implications for the catalytic mechanism of serine proteases

1973 • 239 citations

A comparison of the heme binding pocket in globins and cytochrome b5.

1975 • 237 citations

The crystal structure of myoglobin: Phase determination to a resolution of 2 Å by the method of isomorphous replacement

1961 • 207 citations

An explanation for the rare occurrence of cis peptide units in proteins and polypeptides

1976 • 199 citations

A mathematical model-building procedure for proteins

1966 • 183 citations

Penicillopepsin from Penicillium janthinellum crystal structure at 2.8 Å and sequence homology with porcine pepsin

1977 • 168 citations

Corrections to the amino acid sequence of bovine chymotrypsinogen A.

1966 • 165 citations

Micro diffusion cells for the growth of single protein crystals by means of equilibrium dialysis

1968 • 154 citations

The phylogeny of trypsin-related serine proteases and their zymogens. New methods for the investigation of distant evolutionary relationships

1975 • 152 citations

A least-squares refinement method for isomorphous replacement

1968 • 144 citations

Distribution of Attack on Iron or Zinc Partly Immersed in Chloride Solutions

1942 • 141 citations

Tertiary structural differences between microbial serine proteases and pancreatic serine enzymes

1975 • 132 citations

Low resolution study of crystalline l-lactate dehydrogenase

1969 • 128 citations

High resolution nuclear magnetic resonance studies of the active site of chymotrypsin

1974 • 123 citations

Re-examination of the charge relay system in subtilisin comparison with other serine proteases.

1977 • 119 citations

High resolution nuclear magnetic resonance studies of the active site of chymotrypsin

1974 • 117 citations

The taxonomy of protein structure

1977 • 117 citations

Amino acid sequence alignment of bacterial and mammalian pancreatic serine proteases based on topological equivalences

1978 • 96 citations

Proteolysis and Physiological Regulation

1976 • 89 citations

The pH-dependence of pepsin-catalysed reactions

1969 • 88 citations

Primary Structure of α-Lytic Protease: a Bacterial Homologue of the Pancreatic Serine Proteases

1970 • 83 citations

World List of Computer Programs (Third Edition)

1973 • 72 citations

The active centers of Streptomyces griseus protease 3 and α-chymotrypsin: enzyme-substrate interactions remote from the scissile bond

1976 • 71 citations

Molecular structure of crystalline Streptomyces griseus protease A at 2.8 å resolution

1978 • 65 citations

pH Dependence of chymotrypsin catalysis. Appendix. Substrate binding to dimeric α-chymotrypsin studied by x-ray diffraction and the equilibrium method

1974 • 64 citations

An adaptable disk-oriented automatic diffractometer control program

1975 • 63 citations

Crystal structure analysis of sea lamprey hemoglobin at 2 Å resolution

1973 • 62 citations

A detailed structural comparison between the charge relay system in chymotrypsinogen and in α-chymotrypsin

1976 • 59 citations

An Improved Fractionation System for Pronase on CM-Sephadex

1971 • 52 citations

Amino acid sequence of Streptomyces griseus protease B, a major component of pronase

1974 • 49 citations

Evidence that the activity of elastase is not dependent on the ionization of its N-terminal amino group

1969 • 48 citations

Content of ATP and ADP in Rabbit Blastocysts

1971 • 47 citations

Structural Similarities between α-Lytic Protease of Myxobacter 495 and Elastase

1971 • 46 citations

The active centers of Streptomyces griseus protease 3, α-chymotrypsin, and elastase: enzyme-substrate interactions close to the scissile bond

1976 • 46 citations

The Proteolytic Enzymes of the K-1 Strain of Streptomyces griseus Obtained from a Commercial Preparation (Pronase)

1973 • 38 citations

The structure of α-chymotrypsin. I. The refinement of the heavy-atom isomorphous derivatives at 2.8 Å resolution

1973 • 36 citations

Bias, feedback and reliability in isomorphous phase analysis

1967 • 35 citations

The amino acid sequence and predicted structure of Streptomyces griseus protease A

1974 • 35 citations

Data collection in protein crystallography: capillary effects and background corrections

1974 • 22 citations

Inhibition of Streptomyces griseus protease B by peptide chloromethyl ketones: Partial mapping of the binding site and identification of the reactive residue

1974 • 18 citations

On the accuracy of electron-density distributions with particular reference to structures with non-crystallographic molecular symmetry

1968 • 16 citations

Studies of the Heterogeneity of Streptomyces griseus Protease. Isolation and Characterization of an Alkaline Serine Protease from Commercial Pronase-P Derived from Streptomyces griseus Kl.

1973 • 15 citations

Effect of pH on the Catalytic Activity of Streptomyces griseus Protease 3

1974 • 14 citations

Measurement of Depolarization Ratios in the Raman Spectra of Powdered Crystalline Solids

1971 • 14 citations

Crystal Data for a Bacterial Serine Protease

1969 • 8 citations

An improved background correction for protein X-ray intensities using the partial ω-scan method

1973 • 3 citations