Functional diversity among putative E2 isozymes in the mechanism of ubiquitin-histone ligation.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Anti-cancer Drug Design

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Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

1983 • 1,105 citations

Nucleosome Structure

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Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1987 • 731 citations

Reductive alkylation of amino groups in proteins

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Histones

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Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.

1977 • 436 citations

A glimpse at chromosomal order

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Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation.

1982 • 413 citations

The immunochemical detection and quantitation of intracellular ubiquitin-protein conjugates.

1985 • 383 citations

Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the drosophila genome

1982 • 362 citations

Complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells

1975 • 350 citations

Functional heterogeneity of ubiquitin carrier proteins.

1985 • 281 citations

Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

1985 • 263 citations

ATP-dependent degradation of ubiquitin-protein conjugates.

1984 • 248 citations

Histone 2B can be modified by the attachment of ubiquitin

1980 • 245 citations

Both near ultraviolet radiation and the oxidizing agent hydrogen peroxide induce a 32-kDa stress protein in normal human skin fibroblasts.

1987 • 225 citations

Disappearance of a structural chromatin protein A24 in mitosis: implications for molecular basis of chromatin condensation.

1979 • 194 citations

Metabolism of ubiquitinated histones.

1981 • 193 citations

The protein substrate binding site of the ubiquitin-protein ligase system.

1986 • 178 citations

A modified procedure for fractionating histones

1972 • 177 citations

A method for deriving kinetic constants for two enzymes acting on the same substrate

1971 • 165 citations

Identification of ubiquitinated histones 2A and 2B in Physarum polycephalum. Disappearance of these proteins at metaphase and reappearance at anaphase.

1985 • 142 citations

Deposition of newly synthesized histones: hybrid nucleosomes are not tandemly arranged on daughter DNA strands

1988 • 136 citations

The resolution and characterization of putative ubiquitin carrier protein isozymes from rabbit reticulocytes.

1988 • 133 citations

Histone turnover within nonproliferating cells

1982 • 131 citations

The structure of ubiquitinated histone H2B.

1987 • 114 citations

Poising chromatin for transcription

1987 • 103 citations

Chicken erythrocyte polynucleosomes which are soluble at physiological ionic strength and contain linker histones are highly enriched hi β-globin gene sequences

1987 • 99 citations

Ubiquitin in stressed chicken embryo fibroblasts.

1988 • 96 citations

Deposition of newly synthesized histones: new histones H2A and H2B do not deposit in the same nucleosome with new histones H3 and H4

1987 • 92 citations

Isopeptidase: a novel eukaryotic enzyme that cleaves isopeptide bonds.

1982 • 92 citations

Chromatin conjugate protein A24 is cleaved and ubiquitin is lost during chicken erythropoiesis.

1980 • 72 citations

Specific recognition of calmodulin from Dictyostelium discoideum by the ATP, ubiquitin-dependent degradative pathway.

1985 • 71 citations

Histone segregation of replicating chromatin

1985 • 71 citations

Preferential localization of variant nucleosomes near the 5'-end of the mouse dihydrofolate reductase gene.

1985 • 66 citations

Rapid turnover of the histone-ubiquitin conjugate, protein A24

1981 • 63 citations

Protein ubiquitination: a regulatory post-translational modification.

1987 • 54 citations

The active immunoglobulin kappa chain gene is packaged by non-ubiquitin-conjugated nucleosomes.

1986 • 54 citations

The fluorescence of fluorescamine-amino acids

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Minor Histone 2A Variants and Ubiquinated Forms in the Native H2A:H2B Dimer

1983 • 33 citations

Protein A24 lyase is an isopeptidase

1981 • 32 citations

Synthesis and ubiquitination of histones during myogenesis

1987 • 30 citations

Reduced levels of histones H1o and H1b, and unaltered content of methylated DNA in rainbow trout hepatocellular carcinoma chromatin.

1987 • 19 citations

Assembly of semihistone A24

1982 • 11 citations