Ubiquitin in stressed chicken embryo fibroblasts.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Heat shock, from bacteria to man

1982 • 1,260 citations

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

1983 • 1,105 citations

Abnormal Proteins Serve as Eukaryotic Stress Signals and Trigger the Activation of Heat Shock Genes

1986 • 904 citations

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1987 • 850 citations

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1984 • 533 citations

Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

1984 • 522 citations

The yeast ubiquitin genes: a family of natural gene fusions.

1987 • 500 citations

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

1984 • 456 citations

Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment.

1985 • 428 citations

Ubiquitin-Mediated Pathways for Intracellular Proteolysis

1987 • 409 citations

Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides

1980 • 395 citations

Ubiquitin is a heat shock protein in chicken embryo fibroblasts.

1985 • 392 citations

The immunochemical detection and quantitation of intracellular ubiquitin-protein conjugates.

1985 • 383 citations

Antibodies to two major chicken heat shock proteins cross-react with similar proteins in widely divergent species.

1982 • 316 citations

The ubiquitin system: functions and mechanisms

1985 • 298 citations

Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells. Relationship to the breakdown of abnormal proteins.

1982 • 293 citations

Effect of heat shock on protein degradation in mammalian cells: involvement of the ubiquitin system.

1987 • 235 citations

The dynamic state of heat shock proteins in chicken embryo fibroblasts.

1986 • 227 citations

The Ubiquitin Pathway for the Degradation of Intracellular Proteins

1986 • 213 citations

Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor.

1985 • 196 citations

Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70.

1984 • 175 citations

Molecular genetics: What turns on heat shock genes?

1985 • 171 citations

The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily

1987 • 157 citations

Microinjection of ubiquitin: changes in protein degradation in HeLa cells subjected to heat-shock.

1987 • 145 citations

The Chicken Ubiquitin Gene Contains a Heat Shock Promoter and Expresses an Unstable mRNA in Heat-Shocked Cells

1986 • 137 citations

Evidence for the involvement of H1 histone phosphorylation in chromosome condensation

1980 • 123 citations

The dynamics of ubiquitin pools within cultured human lung fibroblasts.

1987 • 104 citations

The chicken ubiquitin gene contains a heat shock promoter and expresses an unstable mRNA in heat-shocked cells.

1986 • 94 citations

A temperature-sensitive mutant of cultured mouse cells defective in chromosome condensation

1980 • 77 citations

Decrease in uH2A (protein A24) of a mouse temperature‐sensitive mutant

1983 • 44 citations

Changes in chromatin and the phosphorylation of nuclear proteins during heat shock of Achlya ambisexualis.

1984 • 39 citations

Transcript regulation and carboxyterminal extension of ubiquitin in Dictyostelium discoideum

1986 • 33 citations

Disappearance of a basic chromosomal protein from cells of a mouse temperature-sensitive mutant defective in histone phosphorylation

1980 • 31 citations

Comet Dust Closer to Home?

1986 • 6 citations