Transforming growth factor beta and epidermal growth factor alter calcium influx and phosphatidylinositol turnover in rat-1 fibroblasts.

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Epidermal Growth Factor

1979 • 2,964 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

1987 • 786 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+

1986 • 775 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortical slices

1985 • 641 citations

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

1984 • 520 citations

Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration

1986 • 489 citations

A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells

1985 • 456 citations

Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells

1981 • 426 citations

Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver

1985 • 419 citations

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1981 • 392 citations

Polyphosphoinositide phosphodiesterase: regulation by a novel guanine nucleotide binding protein, Gp

1987 • 356 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

The epidermal growth factor-induced calcium signal in A431 cells.

1986 • 297 citations

Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells.

1982 • 263 citations

Identification of Cellular Activation Mechanisms Associated with Salivary Secretion

1986 • 253 citations

Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipases C from bovine brain.

1987 • 243 citations

Epidermal growth factor stimulates the rapid accumulation of inositol (1,4,5)-trisphosphate and a rise in cytosolic calcium mobilized from intracellular stores in A431 cells.

1987 • 202 citations

Reduction of epidermal growth factor receptor affinity by heterologous ligands: Evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C

1984 • 197 citations

Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval.

1985 • 191 citations

Cancer cells. 3: Growth factors and transformation

1985 • 176 citations

Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate.

1987 • 168 citations

Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts.

1986 • 156 citations

Two phases of inositol polyphosphate and diacylglycerol production at fertilisation

1986 • 142 citations

Receptors and phosphoinositide metabolism in the central nervous system

1986 • 104 citations

Further purification of epidermal growth factor by high-performance liquid chromatography

1982 • 103 citations

Activation of 45Ca2+ influx and 22Na+/H+ exchange by epidermal growth factor and vanadate in A431 cells is independent of phosphatidylinositol turnover and is inhibited by phorbol ester and diacylglycerol.

1986 • 101 citations

EGF raises cytosolic Ca2+ in A431 and Swiss 3T3 cells by a dual mechanism

1987 • 89 citations

Stimulation of glycolysis and amino acid uptake in NRK-49F cells by transforming growth factor beta and epidermal growth factor.

1985 • 88 citations

Effect of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) on the growth inhibitory and increased phosphatidylinositol (PI) responses induced by epidermal growth factor (EGF) in A431 cells

1983 • 71 citations

The dependence on Ca2+ of the guanine-nucleotide-activated polyphosphoinositide phosphodiesterase in neutrophil plasma membranes

1986 • 66 citations

Stimulation of glucose uptake by transforming growth factor beta: evidence for the requirement of epidermal growth factor-receptor activation.

1985 • 55 citations

Transforming growth factor beta modulates epidermal growth factor-induced phosphoinositide metabolism and intracellular calcium levels.

1988 • 49 citations

Transcriptional modulation of transin gene expression by epidermal growth factor and transforming growth factor beta.

1988 • 49 citations

Receptor-operated Ca channels

1987 • 31 citations

Mechanism of synergistic induction of DNA synthesis by epidermal growth factor and tumor promoters

1981 • 23 citations