The Role of Fas Ligand and TNF-Related Apoptosis-Inducing Ligand (TRAIL) in the Ocular Immune Response

Identification and characterization of a new member of the TNF family that induces apoptosis

1995 • 2,890 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

1996 • 1,793 citations

The Receptor for the Cytotoxic Ligand TRAIL

1997 • 1,755 citations

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1997 • 1,694 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL

1998 • 1,177 citations

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL

1997 • 1,119 citations

Fas and Fas ligand: lpr and gld mutations

1995 • 906 citations

The Novel Receptor TRAIL-R4 Induces NF-κB and Protects against TRAIL-Mediated Apoptosis, yet Retains an Incomplete Death Domain

1997 • 829 citations

Fas ligand in human serum

1996 • 682 citations

Intracellular Regulation of TRAIL-Induced Apoptosis in Human Melanoma Cells

1998 • 671 citations

A novel receptor for Apo2L/TRAIL contains a truncated death domain

1997 • 650 citations

Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family

1997 • 634 citations

Type I Interferons (IFNs) Regulate Tumor Necrosis Factor–related Apoptosis-inducing Ligand (TRAIL) Expression on Human T Cells: A Novel Mechanism for the Antitumor Effects of Type I IFNs

1999 • 477 citations

Monocyte-mediated Tumoricidal Activity via the Tumor Necrosis Factor–related Cytokine, TRAIL

1999 • 470 citations

TRAIL: a molecule with multiple receptors and control mechanisms

1998 • 459 citations

Human Dendritic Cells Mediate Cellular Apoptosis via Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail)

1999 • 408 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

Regulation of the Proinflammatory Effects of Fas Ligand (CD95L)

1998 • 391 citations

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.

1997 • 375 citations

Ocular immune privilege: the eye takes a dim but practical view of immunity and inflammation

2003 • 334 citations

Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus.

1997 • 291 citations

Fas Ligand: A Sensor for DNA Damage Critical in Skin Cancer Etiology

1999 • 254 citations

Die and Let Live: Eliminating Dangerous Lymphocytes

1996 • 242 citations

Functional Analysis of TRAIL Receptors Using Monoclonal Antibodies

1999 • 241 citations

Enhanced and accelerated lymphoproliferation in Fas-null mice.

1996 • 211 citations

Uptake of Apoptotic Antigen-Coupled Cells by Lymphoid Dendritic Cells and Cross-Priming of CD8+ T Cells Produce Active Immune Unresponsiveness

2002 • 193 citations

TRAIL (Apo-2L) and TRAIL Receptors in Human Placentas: Implications for Immune Privilege

1999 • 191 citations

Interleukin-1β Converting Enzyme–like Protease Involvement in Fas-induced and Activation-induced Peripheral Blood T Cell Apoptosis in HIV Infection. TNF-related Apoptosis-inducing Ligand Can Mediate Activation-induced T Cell Death in HIV Infection

1997 • 188 citations

A vision of cell death: insights into immune privilege

1997 • 177 citations

Fas ligand (CD95 ligand) controls angiogenesis beneath the retina

1999 • 168 citations

Inducible Nonlymphoid Expression of Fas Ligand Is Responsible for Superantigen-Induced Peripheral Deletion of T Cells

1998 • 155 citations

Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L).

1998 • 116 citations

Human retinal pigment epithelial cell-induced apoptosis in activated T cells.

1998 • 104 citations

TRAIL: A Mechanism of Tumor Surveillance in an Immune Privileged Site

2002 • 104 citations

The immune privilege of corneal grafts

2003 • 102 citations

T cell tolerance and autoimmunity

2004 • 99 citations

Membrane Fas Ligand Activates Innate Immunity and Terminates Ocular Immune Privilege

2002 • 81 citations

A Critical Role for Fas Ligand in the Active Suppression of Systemic Immune Responses by Ultraviolet Radiation

1999 • 77 citations

Complete Loss of Fas Ligand Gene Causes Massive Lymphoproliferation and Early Death, Indicating a Residual Activity of gld Allele

2004 • 75 citations

Fas-FasL Interaction Involved in Pathogenesis of Ocular Toxoplasmosis in Mice

1999 • 72 citations

Plasmacytoid Dendritic Cell-Derived IFN-α Induces TNF-Related Apoptosis-Inducing Ligand/Apo-2L-Mediated Antitumor Activity by Human Monocytes Following CpG Oligodeoxynucleotide Stimulation

2003 • 66 citations

Regulation of Fas Ligand-Induced Apoptosis by TNF

2001 • 64 citations

Epithelium-deficient corneal allografts display immune privilege beneath the kidney capsule.

2000 • 61 citations

Apoptosis, tolerance, and regulatory T cells – old wine, new wineskins

2003 • 58 citations

Fas Ligand but Not Complement Is Critical for Control of ExperimentalStaphylococcus aureusEndophthalmitis

2005 • 53 citations

FasL-Fas Interactions Regulate Neovascularization in the Cornea

2003 • 52 citations

The Role of Fas-FasL in the Development and Treatment of Ischemic Retinopathy

2003 • 48 citations

Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion

2002 • 32 citations

Soluble Fas ligand expression in the ocular fluids of uveitis patients

2000 • 20 citations

Characterization of a Novel Cis-element That Regulates Fas Ligand Expression in Corneal Endothelial Cells

1999 • 15 citations