Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Classification and Nomenclature of Viruses

1987 • 1,331 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Phosphorylated Proteins as Physiological Effectors

1978 • 975 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Prevention of Apoptosis by a Baculovirus Gene During Infection of Insect Cells

1991 • 810 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Protein Phosphorylation

1975 • 762 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins.

1992 • 665 citations

The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection

1980 • 554 citations

Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis

1991 • 525 citations

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

1993 • 495 citations

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.

1992 • 396 citations

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1991 • 337 citations

Constitutive expression of (2′–5′) oligo A synthetase confers resistance to picornavirus infection

1987 • 277 citations

2-5A synthetase: assay, distribution and variation with growth or hormone status

1979 • 260 citations

Cytoimitiunotherapy for persistent virus infection reveals a unique clearance pattern from the central nervous system

1986 • 250 citations

Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains

1983 • 241 citations

Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor

1978 • 224 citations

Molecular probes for the development and plasticity of neural crest derivatives

1985 • 196 citations

Forskolin: A labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory, and adenylate cyclase activating properties

1983 • 189 citations

Monoclonal antibodies to lymphocytic choriomeningitis and pichinde viruses: Generation, characterization, and cross-reactivity with other arenaviruses

1981 • 176 citations

Viral persistence

1989 • 148 citations

Constitutive Expression of a 2′,5′-Oligoadenylate Synthetase cDNA Results in Increased Antiviral Activity and Growth Suppression

1989 • 133 citations

Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus

1992 • 122 citations

Restricted expression of viral glycoprotein in cells of persistently infected mice

1982 • 108 citations

Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene.

1989 • 103 citations

The mode of action of nerve growth factor in PC12 cells

1988 • 102 citations

Persistence of RNA Viruses in the Central Nervous System

1986 • 88 citations

T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs.

1993 • 88 citations

Continuing coevolution of virus and defective interfering particles and of viral genome sequences during undiluted passages: virus mutants exhibiting nearly complete resistance to formerly dominant defective interfering particles

1987 • 87 citations

Regulation of ppp(A2'p)nA-dependent RNase levels during interferon treatment and cell differentiation

1985 • 79 citations

Induction of ppp(A2'p)nA-dependent RNase in murine JLS-V9R cells during growth inhibition.

1983 • 79 citations

Interactions between viruses and lymphocytes. I. In vivo replication of lymphocytic choriomeningitis virus in mononuclear cells during both chronic and acute viral infections.

1978 • 76 citations

Cytotoxic T Lymphocyte Control of Acute Lymphocytic Choriomeningitis Virus Infection: Interferon , but Not Tumour Necrosis Factor , Displays Antiviral Activity in vivo

1989 • 72 citations

Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus‐infected mice with anti‐interferon‐γ monoclonal antibody blocks generation of virus‐specific cytotoxic T lymphocytes and virus elimination

1989 • 71 citations

Cytomegalovirus causes a latent infection in undifferentiated cells and is activated by induction of cell differentiation

1981 • 70 citations

Reversible repression and activation of measles virus infection in neural cells.

1982 • 64 citations

Virus-Induced Behavioral Alteration of Mice

1977 • 63 citations

Studies on the role of the 2'-5'-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication

1988 • 61 citations

High resolution in situ hybridization to determine the cellular distribution of lymphocytic choriomeningitis virus RNA in the tissues of persistently infected mice: relevance to arenavirus disease and mechanisms of viral persistence

1991 • 60 citations

Ultrastructural localization of viral antigens in the CNS of mice persistently infected with lymphocytic choriomeningitis virus (LCMV).

1983 • 59 citations

Viral infection of neurons can depress neurotransmitter mRNA levels without histologic injury

1988 • 56 citations

Portraits of Viruses: Arenaviruses

1984 • 50 citations

Viruses Can Cause Disease in the Absence of Morphological Evidence of Cell Injury: Implication for Uncovering New Diseases in the Future

1989 • 45 citations

STRATEGIES OF VIRUS PERSISTENCE

1985 • 41 citations

Viral persistence and disease: Cytopathology in the absence of cytolysis

1991 • 40 citations

Intracellular stability of the interfering activity of a defective interfering influenza virus in the absence of virus multiplication

1987 • 28 citations

Early Inhibition of Acetylcholinesterase and Choline Acetyltransferase Activity in Herpes simplex Virus Type 1 Infection of PC12 Cells

1984 • 27 citations

Inhibition of Pichinde Virus Replication by Actinomycin D

1976 • 25 citations

Effect of Dibutyryl Cyclic AMP on the Induction of Epstein-Barr Virus in Hybrid Cells

1973 • 20 citations

MODULATION OF HERPES SIMPLEX VIRUS (HSV) INFECTION OF CULTURED NEURONAL CELLS BY NERVE GROWTH FACTOR AND ANTIBODY TO HSV

1989 • 19 citations

Plaque Assays and Current Concepts of Regulation in Arenavirus Infections

1973 • 14 citations

Infection of Cultivated Mouse Peritoneal Macrophages with Lymphocytic Choriomeningitis Virus

1978 • 13 citations

Growth Phase Related Loss of Measles Virus Surface-associated Antigens and Cytotoxic Susceptibility in Persistently Infected Cells

1979 • 8 citations

Introduction: Virus-cell interaction in the nervous system

1991 • 8 citations

Alteration of tyrosine hydroxylase activity in PC12 cells infected with herpes simplex virus type 1

1985 • 6 citations

Nutritional requirements for Junin virus production in BHK culture cells.

1974 • 6 citations

The Growth Accelerating Effect of Bittner Virus in Monolayers of Baby Mouse Kidney Cells

1969 • 2 citations