Role of CAAT-enhancer binding protein isoforms in the cytokine regulation of acute-phase plasma protein genes.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP

1990 • 637 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

cAMP stimulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase in rat liver nuclei.

1982 • 410 citations

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription.

1991 • 388 citations

Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response.

1992 • 313 citations

Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family.

1990 • 274 citations

Stimulation of Hepatic Acute Phase Response by Cytokines and Glucocorticoids^a

1989 • 242 citations

Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6.

1991 • 207 citations

The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6.

1989 • 196 citations

Dexamethasone regulation of alpha 1-acid glycoprotein and other acute phase reactants in rat liver and hepatoma cells.

1983 • 194 citations

A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1 alpha induced, NF kappa B mediated trans-activation of the angiotensinogen gene acute-phase response element.

1990 • 180 citations

Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.

1990 • 177 citations

Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes.

1989 • 172 citations

Potential basis for regulation of the coordinately expressed fibrinogen genes: homology in the 5' flanking regions.

1984 • 148 citations

Activation of Early Gene Expression in T Lymphocytes by Oct-1 and an Inducible Protein, OAP ⁴⁰

1991 • 144 citations

Regulation of major acute-phase plasma proteins by hepatocyte-stimulating factors of human squamous carcinoma cells.

1986 • 137 citations

Hepatic acute phase reaction in vivo and in vitro

1989 • 132 citations

An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene.

1990 • 108 citations

Interaction of cytokine- and glucocorticoid-response elements of acute-phase plasma protein genes. Importance of glucocorticoid receptor level and cell type for regulation of the elements from rat alpha 1-acid glycoprotein and beta-fibrinogen genes.

1990 • 108 citations

Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene.

1990 • 105 citations

A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.

1990 • 93 citations

The cytokine response element of the rat alpha 1-acid glycoprotein gene is a complex of several interacting regulatory sequences.

1990 • 89 citations

Sequences Downstream of the Glucocorticoid Regulatory Element Mediate Cycloheximide Inhibition of Steroid Induced Expression from the Rat α₁-Acid Glycoprotein Promoter: Evidence for a Labile Transcription Factor

1988 • 87 citations

Identification of sequences responsible for acute-phase induction of human C-reactive protein

1988 • 87 citations

Transcriptional regulation through cytokine and glucocorticoid response elements of rat acute phase plasma protein genes by C/EBP and JunB.

1991 • 71 citations

cis-acting elements responsible for interleukin-6 inducible C-reactive protein gene expression.

1990 • 70 citations

Distinct Regulation of the Interleukin-1 and Interleukin-6 Response Elements of the Rat Haptoglobin Gene in Rat and Human Hepatoma Cells

1990 • 68 citations

Localization of DNA Sequences Involved in Dexamethasone-Dependent Expression of the Rat α₁-Acid Glycoprotein Gene

1986 • 66 citations

AGP/EBP(LAP) expressed in rat hepatoma cells interacts with multiple promoter sites and is necessary for maximal glucocorticoid induction of the rat alpha-1 acid glycoprotein gene.

1991 • 44 citations

Nucleotide sequence of murine triosephosphate isomerase cDNA

1990 • 44 citations

Regulation of mouse serum amyloid A gene expression in transfected hepatoma cells.

1990 • 39 citations

Expression vectors permitting cDNA cloning and enrichment for specific sequences by hybridization/selection

1988 • 30 citations

Interleukin-6 responsiveness and cell-specific expression of the rat kininogen gene.

1991 • 24 citations

Molecular characterization and acute phase expression of the multiple Mus caroli alpha 1-acid glycoprotein (AGP) genes. Differences in glucocorticoid stimulation and regulatory elements between the rat and mouse AGP genes.

1990 • 21 citations

NF-AB, a liver-specific and cytokine-inducible nuclear factor that interacts with the interleukin-1 response element of the rat alpha 1-acid glycoprotein gene.

1991 • 18 citations

Transcriptional control of the rat alpha 1-acid glycoprotein gene.

1990 • 9 citations