Programmable messengers: a new theory of hormone action

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.

1984 • 498 citations

Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by islet-activating protein, pertussis toxin. A possible role of the toxin substrate in Ca2+-mobilizing receptor-mediated signal transduction.

1985 • 281 citations

Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.

1985 • 213 citations

Reconstitution of catecholamine-stimulated guanosine triphosphatase activity

1983 • 213 citations

Adenosine release from isolated fat cells and its significance for the effects of hormones on cyclic 3?,5?-AMP levels and lipolysis

1973 • 211 citations

A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes.

1980 • 152 citations

Coupling of a single adenylate cyclase of two receptors: adenosine and catecholamine

1978 • 102 citations

Insulin receptor phosphorylation in intact adipocytes and in a cell-free system

1982 • 101 citations

Characteristics of the guanine nucleotide regulatory component of adenylate cyclase in human erythrocyte membranes

1980 • 77 citations

Modulation of adenylate cyclase activity by the physical state of pigeon erythrocyte membrane: 1. Parallel drug-induced changes in the bilayer fluidity and adenylate cyclase activity

1982 • 67 citations