Kinetics of insulin receptor transit to and removal from the plasma membrane.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane

1971 • 8,619 citations

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

Endocytosis

1977 • 1,275 citations

Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture

1974 • 1,037 citations

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells.

1978 • 678 citations

Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons.

1979 • 422 citations

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting.

1976 • 415 citations

Isolation of the Insulin Receptor of Liver and Fat-Cell Membranes

1972 • 397 citations

The subunit structure of the high affinity insulin receptor. Evidence for a disulfide-linked receptor complex in fat cell and liver plasma membranes.

1980 • 388 citations

Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes.

1980 • 252 citations

Alterations in Insulin Binding Induced by Changes in Vivo in the Levels of Glucocorticoids and Growth Hormone*

1978 • 246 citations

Insulin receptor: covalent labeling and identification of subunits.

1979 • 243 citations

Insulin-induced receptor loss in cultured human lymphocytes is due to accelerated receptor degradation.

1981 • 217 citations

On the mechanism of ligand-induced down-regulation of insulin receptor level in the liver cell.

1981 • 198 citations

Photoaffinity labeling of insulin receptor proteins of liver plasma membrane preparations

1980 • 195 citations

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes.

1981 • 188 citations

Down Regulation of Insulin Receptors in Primary Cultures of Adult Rat Hepatocytes in Monolayer*

1978 • 178 citations

Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes.

1977 • 174 citations

Insulin-induced loss of the insulin receptor in IM-9 lymphocytes. A biological process mediated through the insulin receptor.

1980 • 149 citations

Correlation between insulin receptor binding in isolated fat cells and insulin sensitivity in obese human subjects.

1976 • 147 citations

Insulin-induced down-regulation of insulin receptors in 3T3-L1 adipocytes. Altered rate of receptor inactivation.

1982 • 139 citations

Role of insulin receptors in insulin-resistant states

1980 • 138 citations

Biochemical Actions of Hormones

1978 • 135 citations

Post-translational glycosylation-induced activation of aglycoinsulin receptor accumulated during tunicamycin treatment.

1981 • 112 citations

Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes.

1982 • 105 citations

Control of insulin receptor level in 3T3 cells: effect of insulin-induced down-regulation and dexamethasone-induced up-regulation on rate of receptor inactivation.

1982 • 96 citations

Evidence for different pathways for the degradation of insulin and insulin receptor in the chick liver cell.

1982 • 93 citations

Role of glycosylation and protein synthesis in insulin receptor metabolism by 3T3-L1 mouse adipocytes.

1981 • 89 citations

Regulation of insulin receptor metabolism. Differentiation-induced alteration of receptor synthesis and degradation.

1981 • 76 citations

Insulin binding to solubilized material from fat cell membranes: Evidence for two binding species

1978 • 75 citations

The Effect of Glucocorticoids on the Insulin Receptor: An in Vivo and inVitro Study

1981 • 72 citations

Postreceptor alterations in the states of insulin resistance

1980 • 56 citations

Synthesis, processing, and secretion of apolipoprotein B by the chick liver cell.

1982 • 56 citations

Insulin induced changes in insulin binding and insulin-sensitivity of adipocytes

1978 • 55 citations