Characterization of the Human Tryptophan Hydroxylase Gene Promoter

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

1991 • 2,190 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

High Efficiency DNA-Mediated Transformation of Primate Cells

1983 • 652 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Serotonin and appetite

1984 • 579 citations

PCR Technology: Principles and Applications for DNA Amplification

1990 • 512 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

Tryptophan Hydroxylation: Measurement in Pineal Gland, Brainstem, and Carcinoid Tumor

1967 • 463 citations

STRUCTURE OF MELATONIN¹

1959 • 443 citations

Adrenergic signals direct rhythmic expression of transcriptional represser CREM in the pineal gland

1993 • 394 citations

Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor

1988 • 370 citations

Circadian rhythm in rat pineal serotonin and its modifications by estrous cycle and photoperiod

1963 • 361 citations

Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.

1988 • 342 citations

Octamer binding proteins confer transcriptional activity in early mouse embryogenesis.

1989 • 338 citations

Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.

1987 • 328 citations

Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter

1986 • 281 citations

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

1988 • 198 citations

Interrelationships of the Pineal Gland, the Superior Cervical Ganglia and the Photoperiod in the Regulation of the Endocrine Systems of Hamsters1

1966 • 173 citations

Transcriptional regulation of the bovine CYP17 (P-450(17)alpha) gene. Identification of two cAMP regulatory regions lacking the consensus cAMP-responsive element (CRE).

1990 • 134 citations

GLUCOCORTICOIDS AS A REGULATORY FACTOR FOR BRAIN TRYPTOPHAN HYDROXYLASE

1976 • 133 citations

A Suspension Culture of Pinealocytes: Regulation of N-Acetyltransferase Activity

1978 • 132 citations

Upstream promoter element of the human metallothionein-IIA gene can act like an enhancer element.

1985 • 122 citations

Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes.

1989 • 79 citations

Formal Demonstration of the Phosphorylation of Rat Brain Tryptophan Hydroxylase by Ca²⁺/Calmodulin‐Dependent Protein Kinase

1989 • 78 citations

Tryptophan Hydroxylase Synthesis Is Induced by 3′, 5′‐Cyclic Adenosine Monophosphate During Circadian Rhythm in the Rat Pineal Gland

1991 • 72 citations

The Human Tryptophan Hydroxylase Gene

1995 • 69 citations

cAMP-dependent transcription of the human CYP21B (P-450C21) gene requires a cis-regulatory element distinct from the consensus cAMP-regulatory element.

1990 • 69 citations

A circadian rhythm of tryptophan hydroxylase in rat pineals

1977 • 65 citations

Lipopolyamine‐Mediated Transfection Allows Gene Expression Studies in Primary Neuronal Cells

1990 • 63 citations

Interaction of the -170 cyclic AMP response element with the adjacent CCAAT box in the human fibronectin gene promoter.

1992 • 60 citations

The site of cAMP action in the insulin induction of gene expression of acetyl-CoA carboxylase is AP-2.

1993 • 54 citations

Stimulation of [14C] tryptophan 5-hydroxylation by norepinephrine and dibutyryl adenosine 3′, 5′ monophosphate in rat pineal organ cultures

1971 • 48 citations

Isolation and structural characterization of the murine tryptophan hydroxylase gene

1991 • 43 citations

Regulation of tryptophan hydroxylase activity by a cyclic AMP-dependent mechanism in rat striatum

1987 • 43 citations

cAMP regulates G-protein alpha i-2 subunit gene transcription in polarized LLC-PK1 cells by induction of a CCAAT box nuclear binding factor.

1993 • 37 citations

Long-term regulation of serotonergic activity in the rat brain via activation of protein kinase A.

1993 • 36 citations

Regulation of expression of the CYP11A (P450scc) gene in bovine ovarian luteal cells by forskolin and phorbol esters

1993 • 33 citations

Recombinant rabbit tryptophan hydroxylase is a substrate for cAMP-dependent protein kinase

1994 • 29 citations

Circadian Variation of Cyclic AMP in the Rat Pineal Gland

1981 • 25 citations

Post-transcriptional control of tryptophan hydroxylase gene expression in rat brain stem and pineal gland

1991 • 17 citations

A Novel Cyclic AMP Response Element, CACTTGATC, Mediates Forskolin Induction of the Myelin Basic Protein Promoter in the Rat Schwannoma Line, D6P2T

1994 • 16 citations