Octamer binding proteins confer transcriptional activity in early mouse embryogenesis.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Establishment in culture of pluripotential cells from mouse embryos

1981 • 8,424 citations

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.

1981 • 5,629 citations

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1988 • 2,004 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

1984 • 1,518 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl cAMP

1980 • 803 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

Specific interaction between enhancer-containing molecules and cellular components

1984 • 374 citations

Negative regulation of viral enhancers in undifferentiated embryonic stem cells

1985 • 347 citations

Cell-type-specific contacts to immunoglobulin enhancers in nuclei

1985 • 341 citations

Expression of homeo box genes during mouse development: a review.

1988 • 331 citations

undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1

1988 • 323 citations

The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificity.

1987 • 265 citations

Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer.

1987 • 255 citations

Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene

1988 • 255 citations

Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities.

1987 • 240 citations

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

1988 • 238 citations

Autoregulation of fos: the dyad symmetry element as the major target of repression.

1989 • 211 citations

Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor

1989 • 176 citations

Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro.

1988 • 132 citations

Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors.

1985 • 127 citations

Do multigene families regulate vertebrate development?

1988 • 109 citations

The Immunoglobulin Octanucleotide: Independent Activity and Selective Interaction with Enhancers

1987 • 97 citations

Cell-specific activity of the constituent elements of the simian virus 40 enhancer.

1987 • 86 citations

Viral Enhancer Activity in Teratocarcinoma Cells

1985 • 34 citations

Recurrent germ‐line transmission of the teratocarcinoma genome from the METT‐1 culture line to progeny in vivo

1982 • 28 citations