The catalytic mechanism of glutathione reductase as derived from x-ray diffraction analyses of reaction intermediates.

Progress in the Chemistry of Organic Natural Products 109

2019 • 2,082 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

Flavins and Flavoproteins

1977 • 826 citations

Flavins and Flavoproteins

1967 • 599 citations

On the Reaction Mechanism of Yeast Glutathione Reductase

1965 • 484 citations

Flavin coenzymes: at the crossroads of biological redox chemistry

1980 • 395 citations

The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver.

1982 • 336 citations

The structure of the flavoenzyme glutathione reductase

1978 • 279 citations

Mercuric reductase. Purification and characterization of a transposon-encoded flavoprotein containing an oxidation-reduction-active disulfide.

1982 • 267 citations

Three-dimensional structure of glutathione reductase at 2 Å resolution

1981 • 257 citations

フラビン補酵素 生物学的酸化-還元化学の交差点

1980 • 255 citations

Mechanisms of flavin catalysis

1980 • 251 citations

Glutathione-dependent synthesis of deoxyribonucleotides. Characterization of the enzymatic mechanism of Escherichia coli glutaredoxin.

1979 • 239 citations

Glutathione Reductase from Human Erythrocytes

1982 • 238 citations

3 Flavin-Containing Dehydrogenases

1976 • 205 citations

Metabolism and functions of glutathione

1981 • 190 citations

Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates

1978 • 188 citations

ROLE OF CHARGE‐TRANSFER INTERACTIONS IN FLAVOPROTEIN CATALYSIS

1974 • 185 citations

Glutathione Reductase from Human Erythrocytes. Catalytic Properties and Aggregation

1976 • 178 citations

Glutathione Reductase from Human Erythrocytes

1977 • 175 citations

Mechanisms of oxidizing enzymes

1978 • 153 citations

Progress in the Chemistry of Organic Natural Products.

1976 • 147 citations

The Chemical and Electronic Structure of the Neutral Flavin Radical as Revealed by Electron Spin Resonance Spectroscopy of Chemically and Isotopically Substituted Derivatives

1970 • 144 citations

Nicotinamide‐Dependent One‐Electron and Two‐Electron (Flavin) Oxidoreduction : Thermodynamics, Kinetics, and Mechanism

1976 • 120 citations

Progress in bioorganic chemistry

1971 • 112 citations

How many distinct enzymes are responsible for the several cellular processes involving thiol:protein‐disulphide interchange?

1979 • 103 citations

Glutathione reductase from yeast. Differential reactivity of the nascent thiols in two-electron reduced enzyme and properties of a monoalkylated derivative

1981 • 95 citations

Glutathione Reductase from Human Erythrocytes. Amino-Acid Sequence of the Structurally Known FAD-Binding Domain

1981 • 84 citations

Oxidation of thiophenol and nitroalkanes by an electron deficient isoalloxazine

1975 • 77 citations

Spectral evidence for a flavin adduct in a monoalkylated derivative of pig heart lipoamide dehydrogenase.

1976 • 65 citations

Amino acid sequence homology between pig heart lipoamide dehydrogenase and human erythrocyte glutathione reductase.

1982 • 61 citations

Reduction of flavins by thiols. 1. Reaction mechanism from the kinetics of the attack and breakdown steps

1980 • 57 citations

Ion pair formation in pig heart lipoamide dehydrogenase: rationalization of pH profiles for reactivity of oxidized enzyme with dihydrolipoamide and 2-electron-reduced enzyme with lipoamide and iodoacetamide.

1977 • 55 citations

Glutathione Reductase from Human Erythrocytes

1975 • 50 citations

Fructose 1,6-Diphosphatase from Rabbit Liver* *Some of the studies discussed in this chapter were supported by grants from the National Science Foundation (GB 7140X), the Italian Nazionale delle Richerche (U.S.-Italy Cooperative Science Program) and from the National Institutes of Health (GM 11301 and GM 12291). This is Communication No. 201 from the Joan and Lester Avnet Institute of Molecular Biology.

1970 • 47 citations

Cyclic nucleotides, thioldisulfide status of proteins, and cellular control processes

1976 • 44 citations

Yeast Glutathione Reductase

1971 • 42 citations

The Stereospecificity of Glutathione Reductase for Pyridine Nucleotides

1960 • 35 citations

Kinetic studies of the mechanism of pyridine nucleotide dependent reduction of yeast glutathione reductase

1980 • 34 citations

Glutathione reductase in the sea urchin egg. II. Cleavage-associating fluctuation of the activity and its possible regulatory mechanism

1974 • 31 citations

Low resolution structure of human erythrocyte glutathione reductase

1977 • 30 citations

Crystals of human erythrocyte glutathione reductase

1975 • 30 citations

Effect of inducers of drug-metabolizing enzymes on glutathione reductase and glutathione peroxidase in rat liver

1981 • 26 citations

Glutathione Reductase from Human Erythrocytes. Amino-Acid Sequence of a Major Fragment that Links the FAD, NADP and Interface Domains

1979 • 14 citations