Isolation by fluorescence-activated cell sorting of Chinese hamster ovary cell lines with pleiotropic, temperature-conditional defects in receptor recycling

Metal chelate affinity chromatography, a new approach to protein fractionation

1975 • 2,050 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells.

1983 • 636 citations

Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.

1983 • 603 citations

Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

1983 • 558 citations

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

1987 • 479 citations

Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

1990 • 452 citations

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

1987 • 399 citations

Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes

1988 • 377 citations

Receptors compete for adaptors found in plasma membrane coated pits.

1988 • 366 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.

1982 • 357 citations

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome.

1989 • 330 citations

Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization.

1990 • 312 citations

Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics.

1984 • 265 citations

Cyanine dye labeling reagents—carboxymethylindocyanine succinimidyl esters

1990 • 252 citations

A possible role for Na+,K+-ATPase in regulating ATP-dependent endosome acidification.

1989 • 229 citations

Regulation of endocytic pH by the Na+,K+-ATPase in living cells.

1989 • 228 citations

Purification of human plasma α2 macroglobulin and α1 proteinase inhibitor using zinc chelate chromatography

1979 • 213 citations

Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization.

1987 • 190 citations

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment.

1984 • 176 citations

Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses.

1983 • 153 citations

Analysis of macrophage surface receptors. II. Internalization of alpha-macroglobulin . trypsin complexes by rabbit alveolar macrophages.

1979 • 132 citations

Receptor-mediated endocytosis of asialoglycoproteins by rat hepatocytes: receptor-positive and receptor-negative endosomes.

1986 • 121 citations

Relations between the intracellular pathways of the receptors for transferrin, asialoglycoprotein, and mannose 6-phosphate in human hepatoma cells.

1989 • 110 citations

Evidence for reutilization of surface receptors for α-macroglobulin · protease complexes in rabbit alveolar macrophages

1980 • 100 citations

Localization of transferrin receptors and insulin-like growth factor II receptors in vesicles from 3T3-L1 adipocytes that contain intracellular glucose transporters.

1989 • 96 citations

Failure to release iron from transferrin in a Chinese hamster ovary cell mutant pleiotropically defective in endocytosis.

1984 • 80 citations

Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane

1984 • 80 citations

Chinese hamster ovary cell mutants with temperature-sensitive defects in endocytosis. I. Loss of function on shifting to the nonpermissive temperature.

1986 • 77 citations

High-resolution kinetics of transferrin acidification in BALB/c 3T3 cells: exposure to pH 6 followed by temperature-sensitive alkalinization during recycling.

1987 • 71 citations

Insulin-like growth factor I and epidermal growth factor regulate the expression of transferrin receptors at the cell surface by distinct mechanisms.

1987 • 67 citations

Regulation of transferrin receptor cycling by protein kinase C is independent of receptor phosphorylation at serine 24 in Swiss 3T3 fibroblasts.

1987 • 66 citations

Recognition of nucleophile-treated alpha 2-macroglobulin by the alveolar macrophage alpha-macroglobulin . protease complex receptor.

1981 • 65 citations

Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation.

1988 • 62 citations

Analysis of intracellular receptor/ligand sorting in endosomes

1988 • 58 citations

Cohort movement of different ligands and receptors in the intracellular endocytic pathway of alveolar macrophages

1989 • 45 citations

Computer programs for analysis of nucleic acid hybridization, thermal denaturation, and gel electrophoresis data

1979 • 36 citations

Reassessment of fluid‐phase endocytosis and diacytosis in monolayer cultures of human fibroblasts

1988 • 32 citations

Parametric analysis of histograms measured in flow cytometry

1983 • 28 citations

Effect of confluence on endocytosis by 3T3 fibroblasts: increased rate of pinocytosis and accumulation of residual bodies.

1989 • 22 citations

Isolation of Chinese hamster ovary cell lines temperature conditional for the cell-surface expression of integral membrane glycoproteins.

1989 • 22 citations

Impaired lysosomes in a temperature-sensitive mutant of Chinese hamster ovary cells.

1989 • 22 citations

Phorbol esters and calcium ionophores inhibit internalization and accelerate recycling of receptors in macrophages.

1987 • 20 citations

Cell surface proteolysis and down-regulation of the hepatic insulin receptor. Evidence for selective sorting of intact and degraded receptors after internalization.

1988 • 16 citations

Two pathways of transferrin recycling evident in a variant of mouse LMTK? cells

1988 • 12 citations