Effect of alteration of charged residues at the N termini of signal peptides on protein export in Bacillus subtilis

The complete general secretory pathway in gram-negative bacteria

1993 • 1,668 citations

A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides

1983 • 1,143 citations

THE ENZYMOLOGY OF PROTEIN TRANSLOCATION ACROSS THE Escherichia coli PLASMA MEMBRANE

1991 • 442 citations

GENETIC ANALYSIS OF PROTEIN EXPORT IN ESCHERICHIA COLI K12

1985 • 432 citations

Signal sequences

1989 • 417 citations

GENETIC ANALYSIS OF PROTEIN EXPORT IN ESCHERICHIA COLI

1990 • 291 citations

Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein

1984 • 282 citations

Species‐specific variation in signal peptide design Implications for protein secretion in foreign hosts

1989 • 254 citations

Role of positive charge on the amino-terminal region of the signal peptide in protein secretion across the membrane.

1982 • 234 citations

SecA interacts with secretory proteins by recognizing the positive charge at the amino terminus of the signal peptide in Escherichia coli.

1990 • 229 citations

Alteration of the amino terminus of the mature sequence of a periplasmic protein can severely affect protein export in Escherichia coli.

1988 • 163 citations

Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export.

1986 • 107 citations

Idealization of the hydrophobic segment of the alkaline phosphatase signal peptide

1986 • 98 citations

SecA protein: autoregulated ATPase catalysing preprotein insertion and translocation across the Escherichia coli inner membrane

1993 • 85 citations

Analysis of mutational alterations in the hydrophilic segment of the maltose-binding protein signal peptide

1989 • 79 citations

Role of the leader peptide of maltose-binding protein in two steps of the export process

1988 • 72 citations

Role of amino-terminal positive charge on signal peptide in staphylokinase export across the cytoplasmic membrane of Escherichia coli.

1987 • 69 citations

Characterization of a Bacillus subtilis SecA mutant protein deficient in translocation ATPase and release from the membrane

1993 • 68 citations

Suppressor analysis suggests a multistep, cyclic mechanism for protein secretion in Escherichia coli.

1992 • 65 citations

OmpF-Lpp signal sequence mutants with varying charge hydrophobicity ratios provide evidence for a phosphatidylglycerol-signal sequence interaction during protein translocation across the Escherichia coli inner membrane

1993 • 61 citations

Effects of total hydrophobicity and length of the hydrophobic domain of a signal peptide on in vitro translocation efficiency.

1992 • 58 citations

Export of maltose-binding protein species with altered charge distribution surrounding the signal peptide hydrophobic core in Escherichia coli cells harboring prl suppressor mutations

1992 • 57 citations

Effect of signal sequence alterations on export of levansucrase in Bacillus subtilis

1991 • 44 citations

A positively charged region is a determinant of the orientation of cytoplasmic membrane proteins in Escherichia coli.

1990 • 34 citations

Modulation of the effects of mutations in the basic region of the OmpA signal peptide by the mature portion of the protein.

1988 • 28 citations

[19] System for secretion of heterologous proteins in Bacillus subtilis

1990 • 27 citations

Modular expression and secretion vectors for Bacillus subtilis

1992 • 25 citations

Protein Secretion

2014 • 21 citations

Alterations in the hydrophilic segment of the maltose-binding protein (MBP) signal peptide that affect either export or translation of MBP

1992 • 18 citations

The roles of signal peptide and mature protein in RNase (barnase) export from Bacillus subtilis

1993 • 17 citations

A positive residue in the hydrophobic core of the Escherichia coli lipoprotein signal peptide suppresses the secretion defect caused by an acidic amino terminus.

1992 • 10 citations