The XPD complementation group

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Xeroderma Pigmentosum

1974 • 755 citations

THE BIOLOGY OF THE (6–4) PHOTOPRODUCT

1989 • 604 citations

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1990 • 552 citations

A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

1990 • 440 citations

Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain

1990 • 395 citations

Histone acetylation and control of gene expression

1991 • 331 citations

Cellular responses to DNA damage

1983 • 301 citations

(6–4)Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers

1985 • 280 citations

DNA excision-repair processes in human cells can eliminate the cytotoxic and mutagenic consequences of ultraviolet irradiation

1979 • 245 citations

An altered apurinic DNA endonuclease activity in group A and group D xeroderma pigmentosum fibroblasts.

1976 • 224 citations

Restoration of ultraviolet-induced unscheduled DNA synthesis of xeroderma pigmentosum cells by the concomitant treatment with bacteriophage T4 endonuclease V and HVJ (Sendai virus).

1975 • 215 citations

Repair of ultraviolet light damage in a variety of human fibroblast cell strains.

1977 • 209 citations

Five complementation groups in xeroderma pigmentosum

1975 • 199 citations

Apurinic/apyrimidinic endonucleases in repair of pyrimidine dimers and other lesions in DNA.

1980 • 163 citations

A seventh complementation group in excision-deficient xeroderma pigmentosum

1979 • 163 citations

Xeroderma pigmentosum (complementation group D) mutation is present in patients affected by trichothiodystrophy with photosensitivity

1986 • 135 citations

Repair of UV-endonuclease-susceptible sites in the 7 complementation groups of xeroderma pigmentosum a through G

1979 • 132 citations

Xeroderma pigmentosum

1985 • 126 citations

DNA repair characteristics and skin cancers of xeroderma pigmentosum patients in Japan.

1977 • 121 citations

Sodium butyrate stimulates DNA repair in UV-irradiated normal and xeroderma pigmentosum human fibroblasts.

1982 • 120 citations

Immune Function, Mutant Frequency, and Cancer Risk in the DNA Repair Defective Genodermatoses Xeroderma Pigmentosum, Cockayne's Syndrome, and Trichothiodystrophy

1990 • 108 citations

Trichothiodystrophy, a human DNA repair disorder with heterogeneity in the cellular response to ultraviolet light.

1988 • 104 citations

Frequency of UV-induced neoplastic transformation of diploid human fibroblasts is higher in xeroderma pigmentosum cells than in normal cells.

1982 • 101 citations

Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells

1989 • 94 citations

CHO mutant UV61 removes (6–4) photoproducts but not cyclobutane dimers

1989 • 93 citations

Initial rates of DNA incision in UV-irradiated human cells differences between normal, xeroderma pigmentosum and tumour cells

1982 • 89 citations

Further characterization of human fibroblast apurinic/apyrimidinic DNA endonucleases. The definition of two mechanistic classes of enzyme.

1980 • 88 citations

Clinical, Genetic and DNA Repair Studies on a Consecutive Series of Patients with Xeroderma Pigmentosum

1979 • 88 citations

Xeroderma pigmentosum complementation group H falls into complementation group D

1991 • 80 citations

Preferential repair of nuclear matrix associated DNA in xeroderma pigmentosum complementation group C

1984 • 77 citations

Development of a liquid-holding technique for the study of DNA-repair in human diploid fibroblasts

1979 • 70 citations

A rapid procedure for measurement of DNA repair in human fibroblasts and for complementation analysis of xeroderma pigmentosum cells

1980 • 69 citations

Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA endonuclease species with a low apparent K_m

1978 • 68 citations

DNA repair and cancer: speculations based on studies with xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy

1989 • 58 citations

Cancer predisposition, carcinogen hypersensitivity, and aberrant DNA metabolism

1984 • 50 citations

A critical review of permeabilized cell systems for studying mammalian DNA repair

1990 • 48 citations

Photoreversal: dependent release of thymidine and thymidine monophosphate from pyrimidine dimer containing DNA excision fragments isolated from ultraviolet-damaged human fibroblasts

1986 • 46 citations

Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines

1988 • 46 citations

Distribution of u.v.-induced repair events in higher-order chromatin loops in human and hamster fibroblasts

1986 • 43 citations

9 Nucleases Involved in DNA Repair

1982 • 40 citations

U.v. induces long-lived DNA breaks in Cockayne's Syndrome and cells from an immunodeficient individual (46BR): defects and disturbance in post incision steps of excision repair

1983 • 38 citations

Lack of complementation between xeroderma pigmentosum complementation groups D and H

1989 • 38 citations

Intermediate (6-4) photoproduct repair in Chinese hamster V79 mutant V-H1 correlates with intermediate levels of DNA incision and repair replication

1989 • 36 citations

Colony-forming ability of ultraviolet-irradiated xeroderma pigmentosum fibroblasts from different DNA repair complementation groups

1976 • 36 citations

Neurological manifestations of xeroderma pigmentosum in two siblings

1974 • 35 citations

Xeroderma pigmentosum patients from the federal Republic of Germany: Decrease in post-UV colony-forming ability in 30 xeroderma pigmentosum fibroblast strains is quantitatively correlated with a decrease in DNA-incising capacity

1985 • 35 citations

Reduced capacity to repair irradiated adenovirus in fibroblasts from xeroderma pigmentosum heterozygotes.

1980 • 35 citations

Purification and characterization of UV endonucleases I and II from murine plasmacytoma cells

1989 • 30 citations

Xeroderma pigmentosum d-hela hybrids with low and high ultraviolet sensitivity associated with normal and diminished dna repair ability, respectively

1985 • 30 citations

Seven genes for three diseases

1991 • 29 citations

Complementation studies in cells from patients affected by trichothiodystrophy with normal or enhanced UV photosensitivity

1987 • 28 citations

The rate of removal of pyrimidine dimers in quiescent cultures of normal human and xeroderma pigmentosum cells

1984 • 28 citations

HPRT gene organization and expression.

1987 • 28 citations

Kinetic analysis of UV-induced incision discriminates between fibroblasts from different xeroderma pigmentosum complementation groups, XPA heterozygotes and normal individuals

1988 • 28 citations

Cyclobutane-pyrimidine dimer excision in UV-sensitive CHO mutants and the effect of the human ERCC2 repair gene

1990 • 24 citations

Excision repair in xeroderma pigmentosum group C but not group D is clustered in a small fraction of the total genome

1986 • 23 citations

Molecular Evidence for Cleavage of Intradimer Phosphodiester Linkage as a Novel Step in Excision Repair of Cyclobutyl Pyrimidine Photodimers in Cultured Human Cells

1987 • 22 citations

DNA repair deficient photodermatoses.

1990 • 22 citations

XP patients from Germany: Correlation of colony-forming ability, unscheduled DNA synthesis and single-strand breaks after UV damage in xeroderma pigmentosum fibroblasts

1982 • 19 citations

Survival of apurinic SV40 DNA in the D-complementation group of xeroderma pigmentosum

1979 • 15 citations

Xeroderma pigmentosum patients from Germany: repair capacity of 45 XP fibroblast strains of the Mannheim XP Collection as measured by colony-forming ability and unscheduled DNA synthesis following treatment with methyl methanesulfonate and N-methyl-N-nitrosourea

1986 • 11 citations

Delayed sensorineural deafness and skin carcinogenesis in a Japanese xeroderma pigmentosum group D patient.

1988 • 11 citations

Semiautomated autoradiographic measurement of DNA repair in normal and xeroderma pigmentosum cultured human fibroblasts

1980 • 6 citations

Reply to letter by J. H. Robbins

1989 • 4 citations

Normal cellular immunity in Cockayne's syndrome: evidence for the role of defective immunosurveillance in the causation of skin cancer

1988 • 2 citations