Xeroderma pigmentosum patients from Germany: repair capacity of 45 XP fibroblast strains of the Mannheim XP Collection as measured by colony-forming ability and unscheduled DNA synthesis following treatment with methyl methanesulfonate and N-methyl-N-nitrosourea

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1968 • 1,739 citations

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

1963 • 801 citations

Xeroderma Pigmentosum

1974 • 755 citations

EVIDENCE THAT XERODERMA PIGMENTOSUM CELLS DO NOT PERFORM THE FIRST STEP IN THE REPAIR OF ULTRAVIOLET DAMAGE TO THEIR DNA

1969 • 472 citations

XERODERMA PIGMENTOSUM: A HUMAN DISEASE IN WHICH AN INITIAL STAGE OF DNA REPAIR IS DEFECTIVE

1969 • 417 citations

Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction.

1982 • 398 citations

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1968 • 378 citations

Xeroderma pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet radiation.

1978 • 257 citations

Repair Processes for Photochemical Damage in Mammalian Cells

1974 • 245 citations

Methylation of the O⁶Position of Guanine in DNA is the Most Likely Initiating Event in Carcinogenesis by Methylating Agents

1984 • 236 citations

Human Diseases Associated with Defective DNA Repair

1979 • 224 citations

An altered apurinic DNA endonuclease activity in group A and group D xeroderma pigmentosum fibroblasts.

1976 • 224 citations

Biochemical Basis of Chemical Carcinogenesis

1985 • 132 citations

Increased sensitivity of xeroderma pigmentosum cells to some chemical carcinogens and mutagens

1973 • 111 citations

A ninth complementation group in xeroderma pigmentosum, XP I

1985 • 110 citations

Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O4-methyl-thymidine

1973 • 101 citations

Repair of alkylation damage in ultraviolet-sensitive (xeroderma pigmentosum) human cells

1971 • 92 citations

Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA endonuclease species with a low apparent K_m

1978 • 68 citations

Alkylation of the O⁶of Guanine is Only One of Many Chemical Events that May Initiate Carcinogenesis

1984 • 63 citations

The Post-UV Colony-Forming Ability of Normal Fibroblast Strains and of the Xeroderma Pigmentosum Group G Strain

1981 • 57 citations

Xeroderma pigmentosum patients from Germany: Clinical symptoms and DNA repair characteristics

1982 • 54 citations

Evidence that lack of deoxyribonucleic acid repair causes death of neurons in xeroderma pigmentosum

1983 • 51 citations

Biochemical Basis of Chemical Carcinogenesis

1985 • 41 citations

Xeroderma pigmentosum patients from the federal Republic of Germany: Decrease in post-UV colony-forming ability in 30 xeroderma pigmentosum fibroblast strains is quantitatively correlated with a decrease in DNA-incising capacity

1985 • 35 citations

Recent Developments in the Enzymology of Excision Repair of DNA

1981 • 22 citations

XP patients from Germany: Correlation of colony-forming ability, unscheduled DNA synthesis and single-strand breaks after UV damage in xeroderma pigmentosum fibroblasts

1982 • 19 citations

Spontaneous in vitro malignant transformation in a xeroderma pigmentosum fibroblast line

1983 • 18 citations

Extracts of xeroderma pigmentosum group a fibroblasts introduce less nicks into methyl methanesulfonate-treated dna than extracts of normal fibroblasts

1979 • 12 citations

Computational statistics for cell survival curves. II. Evaluation of colony-forming ability of a group of cell strains by the APL function CFAGROUP

1985 • 6 citations

Computational statistics for cell survival curves. I. Evaluation of the colony-forming ability of a single cell strain by the APL function CFALINE

1985 • 6 citations

Analysis of Colony‐Forming Ability of Human Fibroblast Strains by Linear Regression

1987 • 5 citations