Allelic deletions of cell growth regulators during progression of bladder cancer.

The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

1998 • 1,152 citations

Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.

1997 • 751 citations

The p53 Network

1998 • 731 citations

Elevated and Absent pRb Expression is Associated With Bladder Cancer Progression and has Cooperative Effects With p53

1998 • 317 citations

Effect of p21WAF1/CIP1 Expression on Tumor Progression in Bladder Cancer

1998 • 309 citations

PROGNOSTIC MARKERS IN BLADDER CANCER: A CONTEMPORARY REVIEW OF THE LITERATURE

1998 • 285 citations

Allelic loss of chromosome 17p distinguishes high grade from low grade transitional cell carcinomas of the bladder.

1990 • 252 citations

Molecular genetic alterations in superficial and locally advanced human bladder cancer.

1991 • 233 citations

Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors.

1997 • 222 citations

Altered Patterns of MDM2 and TP53 Expression in Human Bladder Cancer

1994 • 192 citations

p53 and RB Expression Predict Progression in T1 Bladder Cancer

1999 • 178 citations

p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer

1995 • 178 citations

Evaluation of epidermal growth factor receptors in bladder tumours

1987 • 168 citations

The relationship of DNA methylation to cancer.

1996 • 157 citations

p53 immunohistochemistry as an independent prognostic factor for superficial transitional cell carcinoma of the bladder

1995 • 142 citations

The Role of p53, MDM2 and c-erb B-2 Oncoproteins, Epidermal Growth Factor Receptor and Proliferation Markers in the Prognosis of Urinary Bladder Cancer

1997 • 107 citations

Abnormal expression of MDM-2 in breast carcinomas

1996 • 104 citations

Matrix metalloproteinase-9 expression in bladder washes from bladder cancer patients predicts pathological stage and grade.

1998 • 90 citations

High prevalence of p16 genetic alterations in head and neck tumours

1999 • 81 citations

Prognostic Significance of Transcription Factor E2F-1 in Bladder Cancer: Genotypic and Phenotypic Characterization

1999 • 71 citations

Mutations of E2F-4 Trinucleotide Repeats in Colorectal Cancer with Microsatellite Instability

1996 • 70 citations

Expression of E-cadherin and alpha-,beta- and gamma-catenins in human bladder carcinomas: are they good prognostic factors?

1997 • 69 citations

p53 and MDM2 in the Development and Progression of Bladder Cancer

1997 • 67 citations

Allelic Loss of Chromosome 17P in Urothelial Cancer: Strong Association with Invasive Phenotype

1992 • 58 citations

Differential apoptotic behaviors of c-myc, N-myc, and L-myc oncoproteins.

1998 • 57 citations

Expression of p21(waf1/cip1) Protein in Transitional Cell Bladder Tumours and Its Prognostic Value

1998 • 53 citations

Pronounced microsatellite instability in transitional cell carcinomas from young patients with bladder cancer

1998 • 50 citations

Loss of Heterozygosity at the p53, RB, DCC and APC Tumor Suppressor Gene Loci in Human Bladder Cancer

1996 • 50 citations

Stereologic estimates of nuclear volume in noninvasive bladder tumors (Ta) correlated with the recurrence pattern

1989 • 36 citations

Detection of p16 gene alteration in cervical cancer using tissue microdissection and LOH study

1999 • 32 citations

Regulation of Myc-dependent apoptosis by p53, c-Jun N-terminal kinases/stress-activated protein kinases, and Mdm-2.

1997 • 32 citations

Blood group ABO and lewis antigen expression during neoplastic progression of human urothelium. Immunohistochemical study of type 1 chain structures

1987 • 31 citations

Bladder tumors. Treated natural history.

1986 • 26 citations

Mapping of gene loci in the Q13?Q15 region of chromosome 12

1995 • 22 citations

Influence of Blood Group Type on the Natural History of Superficial Bladder Cancer

1987 • 18 citations

Correlation of Allelic Loss of the P53 Gene and Tumor Grade, Stage, and Malignant Progression in Bladder Cancer

1997 • 18 citations

Restriction fragment length polymorphism of the L-myc gene is not a prognostic factor in bladder cancer patients

1999 • 12 citations