Loss of Heterozygosity at the p53, RB, DCC and APC Tumor Suppressor Gene Loci in Human Bladder Cancer

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

APC mutations occur early during colorectal tumorigenesis

1992 • 1,901 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples

1991 • 891 citations

Identification of deletion mutations and three new genes at the familial polyposis locus

1991 • 769 citations

A role for both RB and p53 in the regulation of human cellular senescence*1

1991 • 737 citations

Two molecular pathways to transitional cell carcinoma of the bladder.

1994 • 599 citations

Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.

1990 • 543 citations

Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas.

1991 • 385 citations

Allelotype of human bladder cancer.

1994 • 265 citations

Molecular genetic alterations in superficial and locally advanced human bladder cancer.

1991 • 233 citations

Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers.

1992 • 215 citations

Frequent loss of heterozygosity at the DCC locus in gastric cancer.

1992 • 204 citations

Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression

1993 • 159 citations

Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas.

1993 • 139 citations

Accumulated allelic losses in the development of invasive urothelial cancer

1993 • 115 citations

Retinoblastoma gene mutations in primary human bladder cancer

1995 • 88 citations

Tumor Suppressor Gene Allelic Loss in Human Renal Cancers

1993 • 51 citations

Analyses of p53 gene mutations in primary human bladder cancer.

1993 • 43 citations