Characterization of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa. Mutations on the cytoplasmic surface affect transducin activation

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red Pigments

1986 • 1,702 citations

A point mutation of the rhodopsin gene in one form of retinitis pigmentosa

1990 • 1,032 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin

1983 • 689 citations

Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin.

1989 • 663 citations

Visual excitation and recovery

1991 • 530 citations

Constitutively active mutants of rhodopsin

1992 • 513 citations

Isolation and nucleotide sequence of the gene encoding human rhodopsin.

1984 • 495 citations

Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa.

1991 • 492 citations

Effect of Carboxylic Acid Side Chains on the Absorption Maximum of Visual Pigments

1989 • 469 citations

Rhodopsin mutations in autosomal dominant retinitis pigmentosa.

1991 • 455 citations

Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa

1992 • 454 citations

Expression of a synthetic bovine rhodopsin gene in monkey kidney cells.

1987 • 444 citations

Rhodopsin Mutants That Bind But Fail to Activate Transducin

1990 • 377 citations

Three cytoplasmic loops of rhodopsin interact with transducin.

1989 • 370 citations

Mutation spectrum of the rhodopsin gene among patients with autosomal dominant retinitis pigmentosa.

1991 • 364 citations

Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin.

1992 • 307 citations

Preparation and Properties of Phospholipid Bilayers Containing Rhodopsin

1972 • 252 citations

The structure of rhodopsin and the rod outer segment disk membrane

1983 • 248 citations

Rhodopsin: structure, function, and genetics

1992 • 222 citations

A second opsin gene expressed in the ultraviolet-sensitive R7 photoreceptor cells of Drosophila melanogaster

1987 • 215 citations

On the Molecular Genetics of Retinitis Pigmentosa

1992 • 189 citations

Total synthesis of a gene for bovine rhodopsin.

1986 • 179 citations

Autosomal dominant retinitis pigmentosa: Four new mutations in rhodopsin, one of them in the retinal attachment site

1991 • 166 citations

Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons

1984 • 158 citations

Octopus rhodopsin Amino acid sequence deduced from cDNA

1988 • 157 citations

Role of the intradiscal domain in rhodopsin assembly and function.

1990 • 139 citations

The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa.

1991 • 138 citations

An opsin gene expressed in only one photoreceptor cell type of the Drosophila eye

1986 • 134 citations

A 3-bp deletion in the rhodopsin gene in a family with autosomal dominant retinitis pigmentosa.

1991 • 133 citations

Autosomal dominant retinitis pigmentosa: Linkage to rhodopsin and evidence for genetic heterogeneity

1990 • 125 citations

Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin.

1991 • 121 citations

Mouse opsin. Gene structure and molecular basis of multiple transcripts

1990 • 100 citations

Isolation and sequence determination of the chicken rhodopsin gene

1988 • 97 citations

Pro-347-Arg mutation of the rhodopsin gene in autosomal dominant retinitis pigmentosa

1991 • 82 citations

Isolation, DNA sequence and evolution of a color visual pigment gene of the blind cave fish Astyanax fasc1atus

1990 • 51 citations

Movement of the retinylidene Schiff base counterion in rhodopsin by one helix turn reverses the pH dependence of the metarhodopsin I to metarhodopsin II transition.

1993 • 43 citations

Total synthesis and expression of a gene for the α-subunit of bovine rod outer segment guanine nucleotide-binding protein (transducin)

1988 • 21 citations

Characterization of the human rod transducin alpha-subunit gene

1992 • 14 citations