Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype.

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Predicting Coiled Coils from Protein Sequences

1991 • 3,977 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

[1] Production of single-stranded plasmid DNA

1987 • 2,642 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: Regulation by starvation and RAS

1992 • 1,184 citations

A thousand and one protein kinases

1987 • 1,066 citations

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1989 • 848 citations

Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase

1987 • 703 citations

Genetic control of the cell division cycle in yeast *1IV. Genes controlling bud emergence and cytokinesis

1971 • 631 citations

Protein phosphatases come of age

1989 • 616 citations

Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.

1990 • 488 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

α-Helical coiled coils — a widespread motif in proteins

1986 • 350 citations

The SIT4 protein phosphatase functions in late G1 for progression into S phase.

1991 • 340 citations

Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle

1990 • 339 citations

Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae.

1990 • 333 citations

Genetic control of the cell division cycle in yeast

1971 • 325 citations

Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.

1993 • 301 citations

The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number

1983 • 300 citations

Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells.

1990 • 280 citations

CDC55, a Saccharomyces cerevisiae Gene Involved in Cellular Morphogenesis: Identification, Characterization, and Homology to the B Subunit of Mammalian Type 2A Protein Phosphatase

1991 • 276 citations

cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae

1988 • 270 citations

A suppressor of a HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases

1989 • 251 citations

Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid.

1990 • 244 citations

INH, a negative regulator of MPF, is a form of protein phosphatase 2A

1991 • 231 citations

Protein serine/threonine phosphatases; an expanding family

1990 • 225 citations

GENETIC MAPPING IN SACCHAROMYCES IV. MAPPING OF TEMPERATURE-SENSITIVE GENES AND USE OF DISOMIC STRAINS IN LOCALIZING GENES

1973 • 212 citations

Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis.

1991 • 210 citations

The Q-linker: a class of interdomain sequences found in bacterial multidomain regulatory proteins

1989 • 199 citations

Characterization of SIS1, a Saccharomyces cerevisiae homologue of bacterial dnaJ proteins.

1991 • 198 citations

Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes.

1990 • 188 citations

Structure of the Drosophila BicaudalD protein and its role in localizing the posterior determinant nanos

1989 • 185 citations

Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae.

1992 • 180 citations

Yeast PPA2 gene encodes a mitochondrial inorganic pyrophosphatase that is essential for mitochondrial function

1991 • 177 citations

Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway.

1991 • 168 citations

SIT4 protein phosphatase is required for the normal accumulation of SWI4, CLN1, CLN2, and HCS26 RNAs during late G1.

1992 • 144 citations

Negative regulation of mitosis by the fission yeast protein phosphatase ppa2.

1993 • 135 citations

YeastSKO1gene encodes a bZIP protein that binds to the CRE motif and acts as a repressor of transcription

1992 • 113 citations

Yeast galactose permease is related to yeast and mammalian glucose transporters

1989 • 106 citations

Mutation of twins encoding a regulator of protein phosphatase 2A leads to pattern duplication in Drosophila imaginal discs.

1993 • 101 citations

The protein phosphatases involved in cellular regulation

1985 • 94 citations

Protein Phosphatase 2A Potentiates Activity of Promoters Containing AP-1-Binding Elements

1993 • 77 citations

Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis.

1993 • 76 citations

Role of an upstream regulatory element in leucine repression of the Saccharomyces cerevisiae leu2 gene

1984 • 75 citations

Regulatory DNA‐binding proteins in yeast: An overview

1990 • 74 citations

The Saccharomyces cerevisiae SRK1 gene, a suppressor of bcy1 and ins1, may be involved in protein phosphatase function.

1991 • 68 citations

An okadaic acid-sensitive phosphatase negatively controls the cyclin degradation pathway in amphibian eggs.

1991 • 65 citations

The CCR1 (SNF1) and SCH9 protein kinases act independently of cAMP-dependent protein kinase and the transcriptional activator ADR1 in controlling yeast ADH2 expression

1991 • 57 citations

Identification and genetic mapping of CHL genes controlling mitotic chromosome transmission in yeast

1993 • 56 citations

Protein phosphatases and DNA tumor viruses: transformation through the back door?

1991 • 49 citations

Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase.

1993 • 45 citations

Empirical equation that can be used to determine genetic map distances from tetrad data.

1983 • 43 citations

Reversible pseudohyphal growth in haploid Saccharomyces cerevisiae is an aerobic process

1993 • 41 citations

Cloning of a cDNA for rape chloroplast 3-isopropylmalate dehydrogenase by genetic complementation in yeast

1992 • 38 citations

Identification of a glycogen synthase phosphatase from yeast Saccharomyces cerevisiae as protein phosphatase 2A

1991 • 35 citations

Identification and cloning of the CHL4 gene controlling chromosome segregation in yeast.

1993 • 17 citations