Potentiation of the cell specific toxicity of paraquat by 1,3-BIS(2-chloroethyl)-1-nitrosourea (BCNU)

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver

1979 • 4,067 citations

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1976 • 4,013 citations

Stereological Methods. Practical methods for biological morphometry

1979 • 2,038 citations

Purification and characterization of the flavoenzyme glutathione reductase from rat liver.

1975 • 1,938 citations

Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation

1981 • 650 citations

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity

1974 • 540 citations

Redox cycling and sulphydryl arylation; Their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes

1988 • 296 citations

Evidence for energy-dependent accumulation of paraquat into rat lung

1974 • 294 citations

Studies on Cytochrome c Peroxidase

1965 • 276 citations

Biochemical Mechanisms in Chemical-Induced Lung Injury: Roles of Metabolic Activation

1980 • 246 citations

Oxidation of glutathione during hydroperoxide metabolism

1984 • 243 citations

Protective role of the glutathione redox cycle against adriamycin-mediated toxicity in isolated hepatocytes

1981 • 221 citations

Regulation of reductive processes by glutathione

1986 • 213 citations

Antioxidant Defenses in the Lung

1986 • 210 citations

Paraquat toxicity: proposed mechanism of action involving lipid peroxidation.

1976 • 196 citations

Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU" [1,3-bis(chloroethyl)-1-nitrosourea].

1977 • 176 citations

Role of redox cycling and lipid peroxidation in bipyridyl herbicide cytotoxicity

1986 • 133 citations

Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administration

1982 • 101 citations

The formation of mixed disulphides in rat lung following paraquat administration Correlation with changes in intermediary metabolism

1982 • 73 citations

Preferential effects of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on pulmonary glutathione reductase and glutathione/glutathione disulfide ratios: possible implications for lung toxicity.

1984 • 72 citations

The accumulation of diamines and polyamines into rat lung slices

1982 • 68 citations

Effects of Oxidative Stress Caused by Hyperoxia and Diquat. A Study in Isolated Hepatocytes

1986 • 64 citations

The accumulation and localisation of putrescine, spermidine, spermine and paraquat in the rat lung

1988 • 59 citations

Tissue and cellular disposition of paraquat in mice

1980 • 55 citations

Nad+ depletion and cytotoxicity in isolated hepatocytes

1988 • 53 citations

Putrescine and 5-hydroxytryptamine accumulation in rat lung slices: Cellular localization and responses to cell-specific lung injury*1

1987 • 50 citations

The relationship between 5-hydroxytryptamine and paraquat accumulation into rat lung

1976 • 36 citations

Effect of alpha naphthylthiourea on uptake of 5-hydroxytryptamine from the pulmonary circulation.

1981 • 33 citations

Glutathione biosynthesis from sulfur-containing amino acids in enriched populations of Clara and type II cells and macrophages freshly isolated from rabbit lung.

1987 • 33 citations

Paraquat uptake into freshly isolated rabbit lung epithelial cells and its reduction to the paraquat radical under anaerobic conditions.

1986 • 32 citations

The accumulation of cystamine and its metabolism to taurine in rat lung slices

1989 • 28 citations

Role of glutathione reductase during menadione-induced nadph oxidation in isolated rat hepatocytes

1987 • 19 citations

Effects of bis-chloronitrosourea (BCNU) on pulmonary and serum angiotensin converting enzyme activity in rats

1983 • 18 citations

Drug delivery to the respiratory tract

1990 • 16 citations

Alteration of the Redox State of Nadph and Glutathione in Perfused Rabbit Lung By Paraquat

1986 • 16 citations

The Lung as a Target Organ for Toxicity

2020 • 13 citations

A Novel Lung Slice System with Compromised Antioxidant Defenses

1990 • 6 citations